Santa María Vacations from ¥31,235

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The Latest Santa María Vacation Packages

Price found within the past 48 hours. Click for updated prices.
OYO Hotel Y Restaurante Mitla, Oaxaca

OYO Hotel Y Restaurante Mitla, Oaxaca

¥31,235
per person
Nov 5 - Nov 9
found 21 hours ago
Roundtrip flight included
Mexico City (MEX) to Oaxaca Intl. (OAX)
6.8/10 (24 reviews)
Clean room and owner was very accommodating to our needs.

Reviewed on Feb 2, 2026

Hotel Oaxaca Dorado

Hotel Oaxaca Dorado

Calzada Madero
Save 100% on your flight
¥43,288
per person
Nov 5 - Nov 9
found 21 hours ago
Roundtrip flight included
Mexico City (MEX) to Oaxaca Intl. (OAX)
7/10 Good! (34 reviews)
Casa Quiote Hotel Boutique City Center based - Adults Only

Casa Quiote Hotel Boutique City Center based - Adults Only

Oaxaca Centro
Save 100% on your flight
¥71,806
per person
Nov 14 - Nov 16
found 1 day ago
Roundtrip flight included
Mexico City (MEX) to Oaxaca Intl. (OAX)
9/10 Wonderful! (81 reviews)
OYO Hotel Emperador, Oaxaca

OYO Hotel Emperador, Oaxaca

Oaxaca Centro
Save 100% on your flight
¥33,869
per person
Nov 5 - Nov 9
found 21 hours ago
Roundtrip flight included
Mexico City (MEX) to Oaxaca Intl. (OAX)
5.8/10 (272 reviews)
Hotel Boutique Casa Abuela María

Hotel Boutique Casa Abuela María

Oaxaca Centro
Save 100% on your flight
¥74,917
per person
Nov 5 - Nov 9
found 21 hours ago
Roundtrip flight included
Mexico City (MEX) to Oaxaca Intl. (OAX)
8/10 Very Good! (68 reviews)
Very clean! Muy limpio la habitación.

Reviewed on Sep 27, 2026

Where to stay in Santa María

Find the best Santa María areas and neighborhoods for the activities you enjoy most. Learn more about Santa María
A historic courtyard with a fountain, arches, and a dome structure.

Oaxaca Centro

7 out of top 10 points of interest in this area

Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.

A cactus garden with tall cacti and a reflective pond.

Ruta Independencia

If you're spending some time in Ruta Independencia, Oaxaca Ethnobotanical Garden and Jardín Etnobotánico are top sights worth seeing.

A narrow cobblestone street flanked by colorful buildings with balconies and hanging plants.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

A colorful dragon sculpture with vibrant orange, yellow, blue, and green feathers.

Reforma

If you're spending some time in Reforma, Plaza Parque and Plaza Mazari are top sights worth seeing.

An ancient pyramid complex with multiple levels and a large open plaza.

Santa Cruz Xoxocotlán

1 out of top 10 points of interest in this area

Visitors to Santa Cruz Xoxocotlán like its archaeological sites and cafes, and Monte Albán is a sight worth a stop.

Santa María Hotel Deals

Hotel Hacienda

Hotel Hacienda

Av Eduardo Mata 1918 Oaxaca OAX
Fully refundableReserve now, pay when you stay
¥9,409
¥11,280 total
Oct 5 - Oct 6
includes taxes & fees
Hotel Hacienda
Hotel Boutique Naura Centro

Hotel Boutique Naura Centro

Av Hidalgo 918 Oaxaca OAX
Fully refundableReserve now, pay when you stay
¥18,607
¥22,142 total
Sep 28 - Sep 29
includes taxes & fees
Hotel Boutique Naura Centro
Quinta Real Oaxaca

Quinta Real Oaxaca

Calle 5 De Mayo 300 Oaxaca OAX
Fully refundableReserve now, pay when you stay
¥50,192
¥59,728 total
Oct 11 - Oct 12
includes taxes & fees
Quinta Real Oaxaca
See all 993 properties in Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa María vacation package cost?
Starting from only ¥31,235, a vacation package is your passport to low-cost travel. Custom build your Santa María getaway by choosing from our huge range of flights, hotels and rental cars.
How do I get a cheap travel package to Santa María?
One of the easiest ways to save dollars (and time) is to combine your bookings with Expedia. Hotels, flights, rental cars and activities — we've got everything you need. Pick a combination that suits your style and see your savings pile up. Of course, a package deal is never a one-size-fits-all. That's why we offer more than 550 partner airlines and 1,000,000 hotel options from all over the world, which lets you customize your Santa María getaway.
Where should I stay in Santa María?
With fascinating attractions such as Zocalo Square and Church of Santo Domingo de Guzman in this neighborhood, try to find a hotel near them. Auditorio Guelaguetza is another Santa María sight that draws the crowds.
How far in advance should I book my Santa María vacation?
Travelers are generally able to compare international airfares on Expedia within 12 months of departure. Booking late? With a stroke of luck, it's still possible to purchase a cheaper ticket only weeks before your flight.
What does an Expedia Santa María travel package include?
Choose from any combination of hotels, rental cars and flights. Once you've made your booking, you can add tours and activities. Want to pick your fare class? That's easily done too. The choice is all yours when it comes to planning your perfect Santa Marían escape.
What should I know before booking a Santa María travel package?
You can save a tidy sum by combining your hotels, airfares and rental cars. Once you've made your booking, add on fun stuff like activities or sightseeing tours. Your next awesome adventure is only a couple of clicks away.
Can I choose my airline with a Santa Marían Expedia vacation package?
Yes, definitely. Expedia has more than 550 partner airlines to choose from across the world. With such a huge range of choice, finding the perfect carrier to bring you to Santa María won't be hard.
If I'm not able to travel, can I cancel my Santa María vacation package?
Don't stress if you're rethinking your Santa María vacation package — it's possible to change or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We realize your circumstances can change suddenly, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Things to do

Bike tour to the Tule Tree and the Gastronomic Market

Bike tour to the Tule Tree and the Gastronomic Market

¥5,638
per adult
Bike tour to the Tule Tree and the Gastronomic Market
Tour in Oaxaca Monte Alban Mezcal Alebrijes and Barro Negro

Monte Alban, Ancestral Mezcal, Alebrijes and Black Mud Tour

¥5,638
per adult
Monte Alban, Ancestral Mezcal, Alebrijes and Black Mud Tour
Oaxaca de Juarez: Monte Alban Half-Day Tour

Oaxaca de Juarez: Monte Alban Half-Day Tour

¥5,638
per adult
96% of travellers recommend
Oaxaca de Juarez: Monte Alban Half-Day Tour
See all activities in Oaxaca
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.