Santa María Vacations

Book a Hotel + Flight or Car together to unlock savings

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  • Better together

    Save up to ¥45,448 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Where to stay in Santa María

Find the best Santa María areas and neighborhoods for the activities you enjoy most. Learn more about Santa María

Santa María Hotel Deals

Hotel Hacienda

Hotel Hacienda

3.5 out of 5
Av Eduardo Mata 1918, Oaxaca, OAX
Fully refundableReserve now, pay when you stay
The price is ¥8,420 per night from Nov 3 to Nov 4
¥8,420
¥10,020 total
Nov 3 - Nov 4
includes taxes & fees
8.8/10 Excellent! (1,015 reviews)
Clean, Safe and Friendly

Reviewed on Oct 18, 2025

Hotel Hacienda
Hotel Trebol

Hotel Trebol

3 out of 5
Ricardo Flores Magon No. 201, Col. Centro, Oaxaca, OAX
9/10 Wonderful! (1,015 reviews)
.

Reviewed on Oct 22, 2025

Hotel Trebol
Hotel Boutique Naura Centro

Hotel Boutique Naura Centro

3.5 out of 5
Av Hidalgo 918, Oaxaca, OAX
The price is ¥38,350 per night from Oct 29 to Oct 30
¥38,350
¥45,636 total
Oct 29 - Oct 30
includes taxes & fees
9/10 Wonderful! (938 reviews)
Esta muy bonita la finca, El personal muy atento y amable

Reviewed on Oct 17, 2025

Hotel Boutique Naura Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa María vacation package cost?
Starting from only , a vacation package is your passport to low-cost travel. Custom build your Santa María getaway by choosing from our huge range of flights, hotels and rental cars.
How do I get a cheap travel package to Santa María?
One of the easiest ways to save dollars (and time) is to combine your bookings with Expedia. Hotels, flights, rental cars and activities — we've got everything you need. Pick a combination that suits your style and see your savings pile up. Of course, a package deal is never a one-size-fits-all. That's why we offer more than 550 partner airlines and 1,000,000 hotel options from all over the world, which lets you customize your Santa María getaway.
Where should I stay in Santa María?
With fascinating attractions such as Zocalo Square and Church of Santo Domingo de Guzman in this neighborhood, try to find a hotel near them. Auditorio Guelaguetza is another Santa María sight that draws the crowds.
How far in advance should I book my Santa María vacation?
Travelers are generally able to compare international airfares on Expedia within 12 months of departure. Booking late? With a stroke of luck, it's still possible to purchase a cheaper ticket only weeks before your flight.
What does an Expedia Santa María travel package include?
Choose from any combination of hotels, rental cars and flights. Once you've made your booking, you can add tours and activities. Want to pick your fare class? That's easily done too. The choice is all yours when it comes to planning your perfect Santa Marían escape.
What should I know before booking a Santa María travel package?
You can save a tidy sum by combining your hotels, airfares and rental cars. Once you've made your booking, add on fun stuff like activities or sightseeing tours. Your next awesome adventure is only a couple of clicks away.
Can I choose my airline with a Santa Marían Expedia vacation package?
Yes, definitely. Expedia has more than 550 partner airlines to choose from across the world. With such a huge range of choice, finding the perfect carrier to bring you to Santa María won't be hard.
If I'm not able to travel, can I cancel my Santa María vacation package?
Don't stress if you're rethinking your Santa María vacation package — it's possible to change or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We realize your circumstances can change suddenly, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Discover the most popular places to visit in Santa María

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.