Santa Maria Vacations from ￥45,678

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ￥109,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Santa Maria Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Dimora Bellini residenza d' epoca

Dimora Bellini residenza d' epoca

3 out of 5
Palermo Historical Center
Price was ￥66,016, price is now ￥45,678 per person
￥45,678
per person
Dec 3 - Dec 7
found 23 hours ago
Roundtrip flight included
Rome (FCO) to Palermo (PMO)
9.2/10 Wonderful! (175 reviews)

Eurostars Centrale Palace

Eurostars Centrale Palace

4 out of 5
Palermo Historical Center
Save 100% on your flight
Price was ￥95,162, price is now ￥62,030 per person
￥62,030
per person
Dec 3 - Dec 7
found 23 hours ago
Roundtrip flight included
Rome (FCO) to Palermo (PMO)
8.4/10 Very Good! (1,006 reviews)

Delle Vittorie Luxury Suites & Rooms

Delle Vittorie Luxury Suites & Rooms

3 out of 5
Palermo Historical Center
Save 100% on your flight
Price was ￥81,784, price is now ￥59,484 per person
￥59,484
per person
Dec 3 - Dec 7
found 23 hours ago
Roundtrip flight included
Rome (FCO) to Palermo (PMO)
9.6/10 Exceptional! (578 reviews)
This property is a luxury hotel B&B. The location is excellent. The staff is very attentive, informative and very friendly. The room was the best during our long trip - with 10 different hotels. Double sink. Shower and bath. Very comfortable bed. A well maintained and spacious suite. I would highly recommend.

Reviewed on Oct 27, 2026

Alkamuri Posh Hotel & Spa

Alkamuri Posh Hotel & Spa

4 out of 5
Price was ￥72,316, price is now ￥53,998 per person
￥53,998
per person
Dec 3 - Dec 7
found 23 hours ago
Roundtrip flight included
Rome (FCO) to Palermo (PMO)
9/10 Wonderful! (14 reviews)

Artemisia Palace Hotel

Artemisia Palace Hotel

4 out of 5
Politeama
Price was ￥71,238, price is now ￥54,329 per person
￥54,329
per person
Dec 3 - Dec 7
found 23 hours ago
Roundtrip flight included
Rome (FCO) to Palermo (PMO)
8.6/10 Excellent! (532 reviews)
The staff is excellent…..

Reviewed on Oct 16, 2026

Find the Best Santa Maria Vacation Packages

Santa Maria Hotel Deals

Villa Samantha, Luxury Villa less than 1km from the beach

Villa Samantha, Luxury Villa less than 1km from the beach

Mazara del Vallo TP Sicily
Get rates
Villa Samantha, Luxury Villa less than 1km from the beach
SEAWATER HOTEL BIO & BEAUTY SPA

SEAWATER HOTEL BIO & BEAUTY SPA

4 out of 5
Via Trapani 330 Marsala TP
The price is ￥8,664 per night from Nov 4 to Nov 5
￥8,664
￥10,585 total
Nov 4 - Nov 5
includes taxes & fees
SEAWATER HOTEL BIO & BEAUTY SPA
Mangia's Selinunte Resort

Mangia's Selinunte Resort

4 out of 5
Contrada Belice di Mare 3 Castelvetrano TP
Get rates
Mangia's Selinunte Resort
See all 1,208 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Santa Maria

Marsala: Winery Tour with Wine Tasting and Local Products

Marsala: Winery Tour with Wine Tasting and Local Products

￥4,144
per adult
100% of travellers recommend
Marsala: Winery Tour with Wine Tasting and Local Products
Discovering Marsala in the historic Pellegrino Cellars

Discovering Marsala in the historic Pellegrino Cellars

￥3,964
per adult
Discovering Marsala in the historic Pellegrino Cellars
Sicilian Walk and Talk Experience in Marsala

Sicilian Walk and Talk Experience in Marsala

￥4,504
per adult
Sicilian Walk and Talk Experience in Marsala
See all activities in Santa Maria

Frequently asked questions

How much does a Santa Maria vacation package cost?
You'll find cheap prices from ￥45,678 on Expedia for your Santa Maria getaway. However, factors like the season, length of stay and your choice of hotel will influence how much your vacation to Santa Maria costs.
What are the cheapest months to go to Santa Maria?
You can generally find reduced prices and greater availability in January, February and March. Check out our cheap Santa Maria vacation packages and you could get some great off-season deals.
How many days is enough for Santa Maria?
The ideal duration for your Santa Maria vacation depends on what you'd like to do and see. Usually, a few days to a week will give you plenty of time to visit all the leading attractions and discover some hidden treasures along the way.
How to find the best Santa Maria package deals?
Start your search for a Santa Maria package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the perfect Santa Maria package deal straight away, simply change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santa Maria escape off to a flying start.
Is it cheaper to book a Santa Maria vacation as a package?
You can enjoy significant savings on your Santa Maria escape by booking a tailored vacation package. Click on the "Package" heading, then enter your travel dates and destination to browse the best hotel prices and airfares. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santa Maria?
Secure amazing discounts by booking your flights in advance with Expedia. If spontaneity is more your thing, grab one of our last-minute deals for an impromptu Santa Maria getaway.
How to plan a trip to Santa Maria?

  1. Pick the best time to travel: Your schedule, preferred season and the type of weather you enjoy can all influence your decision on when to go to Santa Maria.
  2. Set a budget: Consider costs like flights, transportation and food when calculating how much to put aside for your trip to Santa Maria. Then, choose a hotel that fits your budget, whether that's a low-cost stay or a more luxurious retreat.
  3. Decide how long to go away for: Now that you know more about Santa Maria, you can figure out the perfect length of your break. Pull together a rough plan and allocate enough time to get through everything on your must-do list.
  4. Bundle your hotel and flights: Awesome destination, check. Length of stay, check. Now all that's left is to pick a Santa Maria vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.