The Best Hotels Closest to Santa Fe Depot Museum in Gainesville for 2026

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Our top choices for Santa Fe Depot Museum hotels

A two-story house with a swimming pool, outdoor furniture, and a well-maintained garden.

A beach with a sunset, waves, and a few trees and structures in the distance.

A wooden deck with a hot tub, outdoor furniture, and a welcome sign on a building.

A two-story house with a tiled roof, multiple windows, and a front porch.

1. The Lancaster Manor B&B

0.8 km from Santa Fe Depot Museum

Jeffrey

￥32,842

￥37,769 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel lobby with a wooden ceiling, a large TV, a sofa, a coffee table, and a patterned floor.

A modern hotel lobby with a wooden ceiling, a reception desk, a seating area with green sofas, and a visible kitchen in the background.

A spacious indoor area with a curved ceiling, a central bar area, multiple seating arrangements, and a large table in the foreground.

A hotel with a modern facade, a covered entrance, and a parking lot.

2. Fairfield Inn & Suites by Marriott Gainesville I-35

1.8 km from Santa Fe Depot Museum

BALTAZAR

￥15,163

￥17,438 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel room with a large bed, a desk, a chair, and a sofa.

A gym with treadmills, elliptical machines, and weight machines.

A motel with a covered parking area and multiple cars parked.

A Days Inn reception area with a stone counter, a dining area with tables and chairs, and a large window on the right side.

3. Days Inn by Wyndham Gainesville

2.5 km from Santa Fe Depot Museum

Tina

￥9,817

￥11,290 total

includes taxes & fees

Nov 15 - Nov 16

A buffet with labeled containers of omelets and other dishes.

A hotel room with a bed, a desk, a chair, a sofa, and a ceiling fan.

A lobby with a coffee table, armchairs, a sofa, and lamps.

A Holiday Inn Express hotel with a covered entrance, multiple windows, and a brick facade.

4. Holiday Inn Express & Suites Gainesville by IHG

1.1 km from Santa Fe Depot Museum

Brent

￥12,826

￥14,750 total

includes taxes & fees

Nov 11 - Nov 12

A spacious living area with a sofa, a glass-top coffee table, a desk with a computer, and a magazine rack. There is a dining area with tables and chairs in the background.

A hotel hallway with carpeted floors, doors on both sides, and a ceiling with recessed lighting.

A hotel room with two beds, a desk, a chair, a TV, and a large window with curtains.

A reception desk with a mosaic tile design, a framed welcome sign, and a small table with a blue sign.

5. Super 8 by Wyndham Gainesville TX

2.7 km from Santa Fe Depot Museum

Sid

￥10,908

￥12,544 total

includes taxes & fees

Nov 15 - Nov 16

A large indoor swimming pool with clear views through tall windows, a lounge chair, and a table with chairs.

A hotel kitchen with a central island, wooden cabinets, and a breakfast bar.

A hotel room with a large bed, wooden headboard, bedside tables, a desk with a chair, and a television.

A reception desk with a sign reading "Comfort Suites." There are two digital kiosks and a reception counter.

6. Comfort Suites Gainesville

2.5 km from Santa Fe Depot Museum

Tammera

￥11,239

￥12,925 total

includes taxes & fees

Nov 15 - Nov 16

A kitchen with a countertop, a refrigerator, a ceiling fan, and a window.

A small office with a desk, computer, chair, and a clock on the wall.

A bedroom with a bed, a desk, a chair, an air conditioning unit, a door, and a window.

A hotel room with a desk, a television on a stand, a mirror, and a small cabinet.

7. Budget Host Motel Gainesville

2.7 km from Santa Fe Depot Museum

Mark

￥9,485

￥10,908 total

includes taxes & fees

Nov 14 - Nov 15

A spacious living area with a stone accent wall, a brown sofa, and a kitchen in the background.

A long corridor with a dining area featuring tables and chairs, a kitchen area, and a reception desk.

A hotel room with two beds, a desk with a TV, a mirror, and a lamp.

A gazebo with a roof and open sides, surrounded by grass and trees.

8. Loyalty Inn Gainesville

3 km from Santa Fe Depot Museum

Jimmy

￥7,390

￥8,500 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with two beds, a desk with a chair, a television, and a minibar.

A breakfast bar with coffee machines, a refrigerator, and a seating area with a wooden table and chairs.

A modern lobby with a green leather sofa, a glass coffee table, and potted plants.

Two refrigerated beverage dispensers labeled 'CHILLED' and 'FROZEN' with various drinks inside.

9. Quality Inn Gainesville

0.9 km from Santa Fe Depot Museum

Roxann

￥8,694

￥10,117 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, a desk with a computer, a TV, a microwave, and a refrigerator.

A spacious dining area with multiple wooden tables and chairs, a counter with food service equipment, and large windows with blinds.

A modern lobby with a green sofa, blue armchairs, a glass coffee table, and potted plants.

10. Suburban Studios Gainesville

0.9 km from Santa Fe Depot Museum

Lynzee

￥7,838

￥9,014 total

includes taxes & fees

Oct 21 - Oct 22

A spacious living room with patterned sofas, a coffee table, and a flat-screen TV mounted on the wall.

A modern kitchen with a large island, bar stools, and a flat-screen TV.

A hotel room with two beds, a desk, a TV, and a window.

A Best Western hotel with a brick facade, a covered entrance, and stone pillars.

11. Best Western Red River Inn & Suites

13.9 km from Santa Fe Depot Museum

Douglas

￥15,174

￥16,994 total

includes taxes & fees

Nov 15 - Nov 16

A rustic interior with wooden floors, hanging plants, and a rustic ceiling.

An outdoor seating area with wooden chairs and tables, surrounded by trees and string lights.

A wooden cabin with a porch, surrounded by trees and a garden with yellow flowers.

A backyard with a swimming pool, a wooden pergola, and a stone patio.

12. Oak Meadow Ranch

15 km from Santa Fe Depot Museum

Isaac

￥22,252

￥33,517 total

includes taxes & fees

Nov 9 - Nov 10

A spacious kitchen with checkered flooring, wooden cabinets, and various appliances.

A modern hotel room with a large bed, a desk, and a view of the cityscape.

A gym with treadmills, elliptical machines, and a weight bench.

A kitchen with wooden cabinets, a refrigerator, and a tiled floor.

13. Hampton Inn & Suites Gainesville

6.4 km from Santa Fe Depot Museum

Charlie

￥11,537

￥13,320 total

includes taxes & fees

Nov 15 - Nov 16

A spacious lobby with a reception desk, a staircase, and seating area.

A hotel with a red roof, a covered entrance, and a sign for La Quinta Inn & Suites.

A swimming pool with a metal railing, surrounded by lounge chairs and a door in the background.

A spacious lobby with a fireplace, patterned wallpaper, and modern seating arrangements.

14. La Quinta Inn & Suites by Wyndham Gainesville

5.7 km from Santa Fe Depot Museum

Teresa

￥13,324

￥15,630 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, each with a green headboard, white bedding, and red accents. There are abstract paintings on the wall above the beds.

A small, modern room with a gray sofa, a green armchair, a bed with a red blanket, a white pillow, and a painting on the wall.

A building with a sign reading "Lindsay Inn" and a covered entrance area with columns.

A bathroom with a toilet, a shower curtain, a towel rack with towels, and a toilet paper holder.

15. Lindsay Inn

7.9 km from Santa Fe Depot Museum

Tammera

￥11,066

￥12,394 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a bed, bedside table, lamp, and a television on a dresser.

A kitchen with wooden cabinets, a black countertop, and a black rug.

A building with a covered entrance, a clock, and a sign with a flag.

A hotel room with a bed, bedside lamps, a telephone, a nightstand, a window with curtains, and a door.

16. OYO Hotel Valley View TX, I-35

16.5 km from Santa Fe Depot Museum

Brian

￥9,651

￥11,387 total

includes taxes & fees

Nov 12 - Nov 13

A modern living room with a fireplace, two bean bag chairs, a television, and large windows with blinds.

A modern hotel lobby with dark wood flooring, comfortable seating, a flat-screen TV, and a reception desk.

A living room with a sofa, two bean bags, a coffee table, and a TV mounted on the wall.

A modern restaurant with a bar area, dark wooden flooring, and contemporary furniture.

17. Red River Inn And Suites

13.9 km from Santa Fe Depot Museum

Troy

￥15,650

￥17,528 total

includes taxes & fees

Nov 15 - Nov 16

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Compare popular hotels close to Santa Fe Depot Museum

Property	Star rating	Guest rating
The Lancaster Manor B&B	10.0 Exceptional 115 reviews	View
Fairfield Inn & Suites by Marriott Gainesville I-35	8.6 Excellent 1,004 reviews	View
Days Inn by Wyndham Gainesville	7.8 Good 1,000 reviews	View
Holiday Inn Express & Suites Gainesville by IHG	7.8 Good 1,000 reviews	View
Super 8 by Wyndham Gainesville TX	7.2 Good 1,002 reviews	View

Top Santa Fe Depot Museum Hotel Reviews

La Quinta Inn & Suites by Wyndham Gainesville

10/10 Excellent

"Hotel very clean."

Loyalty Inn Gainesville

10/10 Excellent

"A nice peaceful place to stay. Good price."

Fairfield Inn & Suites by Marriott Gainesville I-35

8/10 Good

"Courtney at the front desk was awesome. Very helpful, friendly and nice. The chair in our room was very wobbly, she found us a replacement right away. The carpet had some spots on it, but the room had a couch and a desk and chair. It was noisy. The bed was clean and comfortable and the shower was great."

Oak Meadow Ranch

10/10 Excellent

"Amazing adventure! Book the Tranquility Cabin and the Serenity Slot experience! We’re still on a high from this experience! It was an absolutely amazing adventure that exceeded every single one of our expectations. The entire process was seamless and incredibly well-organized. The guides/hosts were phenomenally knowledgeable, patient, and full of infectious energy that made the day even more special. It balanced pure excitement with wonderful hospitality, leaving both of us completely captivated. It was genuinely a life-disrupting, beautiful memory that we will treasure forever. Don't even hesitate—just book it! For us, we’re looking forward to arranging to bring more family with us next time for a possible giraffe adventure! Thank you again Oak Meadow Ranch for such a one-a-lifetime adventure!"

Holiday Inn Express Hotel & Suites Gainesville by IHG

10/10 Excellent

"Very clean property….also very convenient location."

Super 8 by Wyndham Gainesville TX

10/10 Excellent

"This is an older property but for the most part is nice, we felt safe. Really like the big fridge it kept our drinks very cold better than most motels. Only thing is all the road construction around the area. If you’re bougie this probably won’t be the place for you."

The Lancaster Manor B&B

10/10 Excellent

"You will not find a better couple to host you and you will not find a place with more character than this mansion. Everything was perfect from the check in to the food. We will be back!"

Budget Host Motel Gainesville

10/10 Excellent

"Every\nThing was excellent, clean room.Good parking , good air conditioner , nice staff"

King Ranch -Stay with Puzzles and Jigsaw the Giraffe

8/10 Good

"we did a monday to friday stay at the king ranch suite, which was an amazing experience. The whole property was also a cool experience with a whole array of animals to interact with. They had a nice outdoor pool which was a 5 minute walk from the room, but not too bad. Staff nice also. No complaints at all, except lack of food/beverages options on the property, you need to basically order uber eats and everything is far away and doesnt taste good. Maybe do some shopping before you come-they have a fridge in the room so you can store essentials to at least have a basic breakfast. Great place to stay for a day, max 2 days; we definitely overdid it with our 5 days and actually left a day early to have a chance to see Dallas before our flight back. Overall I highly recommend them for a short trip you will have a great experience!"

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

7.6/10 (89 reviews)

After visiting Cooke County Courthouse, make a plan to see the other sights and activities in Gainesville. While you're in the area, find time to visit its casinos.

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Depot Park

Depot Park is just one of the places to see in Gainesville, so why not enjoy the other things to explore during your travels? While in this family-friendly area, find time to visit its casinos.

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Butterfield Stage Players

7.2/10 (64 reviews)

You can get tickets for a performance at Butterfield Stage Players during your trip to Gainesville. While you're in the area, find time to visit its casinos.

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State Theater

7.4/10 (54 reviews)

You can make plans for a show at State Theater during your stay in Gainesville. While you're in the area, find time to visit its casinos.

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Morton Museum

7.2/10 (68 reviews)

You can spend time browsing the exhibits at Morton Museum during your travels in Gainesville. While you're in the area, find time to visit its casinos.

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Tom Thumb Park

After visiting Tom Thumb Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

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Jaycee Park

After visiting Jaycee Park, make a plan to see the other sights and activities in Gainesville. While in this family-friendly area, find time to visit its casinos.

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Gainesville War Memorial

8.0/10 (109 reviews)

Find out about the history of Gainesville when you take a trip to Gainesville War Memorial. While you're in the area, find time to visit its casinos.

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Frequently asked questions

What's the area like around Santa Fe Depot Museum?

Santa Fe Depot Museum is located in a welcoming area of Gainesville known for its top-notch casinos. If you're looking for a convenient place to stay, check out the 17 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Santa Fe Depot Museum?

Quality Inn Gainesville is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and free parking. It's located just a short 0.5 mi (0.9 km) from Santa Fe Depot Museum. Other good options within a short distance include Suburban Studios Gainesville and Holiday Inn Express Hotel & Suites Gainesville by IHG.

How many hotels should I expect to find near Santa Fe Depot Museum?

Expedia has 17 hotels and other accommodations within a mile from Santa Fe Depot Museum.

If I need to cancel the hotel reservation for my stay near Santa Fe Depot Museum, will I receive a refund?

Yes, most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to get the best deals near Santa Fe Depot Museum.

Where can I learn more about changing or cancelling my trip in the area near Santa Fe Depot Museum?

To find more details about picking new dates or cancelling your stay near Santa Fe Depot Museum, head over to our customer service page.

What can I see and do near Santa Fe Depot Museum?

You can enjoy live performances at Butterfield Stage Players and State Theater. Get outside and spend some time strolling around Leonard Park, Tom Thumb Park, and Jaycee Park. Gainesville War Memorial and Frank Buck Zoo are both worth a visit while you're checking out the area.

Find hotels near Santa Fe Depot Museum, Gainesville from ￥8,500

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Our top choices for Santa Fe Depot Museum hotels

1. The Lancaster Manor B&B

2. Fairfield Inn & Suites by Marriott Gainesville I-35

3. Days Inn by Wyndham Gainesville

4. Holiday Inn Express & Suites Gainesville by IHG

5. Super 8 by Wyndham Gainesville TX

6. Comfort Suites Gainesville

7. Budget Host Motel Gainesville

8. Loyalty Inn Gainesville

9. Quality Inn Gainesville

10. Suburban Studios Gainesville

11. Best Western Red River Inn & Suites

12. Oak Meadow Ranch

13. Hampton Inn & Suites Gainesville

14. La Quinta Inn & Suites by Wyndham Gainesville

15. Lindsay Inn

16. OYO Hotel Valley View TX, I-35

17. Red River Inn And Suites

Compare popular hotels close to Santa Fe Depot Museum

Top Santa Fe Depot Museum Hotel Reviews

La Quinta Inn & Suites by Wyndham Gainesville

Loyalty Inn Gainesville

Fairfield Inn & Suites by Marriott Gainesville I-35

Oak Meadow Ranch

Holiday Inn Express Hotel & Suites Gainesville by IHG

Super 8 by Wyndham Gainesville TX

The Lancaster Manor B&B

Budget Host Motel Gainesville

King Ranch -Stay with Puzzles and Jigsaw the Giraffe

Other attractions near Santa Fe Depot Museum

Cooke County Courthouse

Depot Park

Butterfield Stage Players

State Theater

Morton Museum

Tom Thumb Park

Jaycee Park

Gainesville War Memorial

Frequently asked questions