Santa Cruz Vacations

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  • Plan, book, travel with confidence

  • Better together

    Save up to ¥109,000 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Find the Best Santa Cruz Vacation Packages

Santa Cruz Hotel Deals

DoubleTree by Hilton Iquitos

DoubleTree by Hilton Iquitos

5 out of 5
Napo 258 Iquitos
Fully refundableReserve now, pay when you stay
The price is ¥18,904 per night from Jul 21 to Jul 22
¥18,904
¥21,173 total
Jul 21 - Jul 22
8.8/10 Excellent! (377 reviews)
"Clean room good location"

Reviewed on Jul 3, 2026

DoubleTree by Hilton Iquitos
El Dorado Classic Hotel

El Dorado Classic Hotel

3 out of 5
Napo 362 Iquitos Loreto
Fully refundableReserve now, pay when you stay
The price is ¥6,352 per night from Jul 14 to Jul 15
¥6,352
¥7,896 total
Jul 14 - Jul 15
8.2/10 Very Good! (139 reviews)
"This was my 3rd one-night stay at the El Dorado Classic. This last visit I stayed on the 4th floor and the suite was basic but very clean and the bed was quite comfortable. There was very hot water , which wasn’t available during previous stays in lower rooms. I did observe that the hot water began ..."

Reviewed on Jul 3, 2026

El Dorado Classic Hotel
Hotel de Turistas Iquitos

Hotel de Turistas Iquitos

3 out of 5
Napo Iquitos Loreto
Fully refundableReserve now, pay when you stay
The price is ¥10,194 per night from Jul 29 to Jul 30
¥10,194
¥10,194 total
Jul 29 - Jul 30
8.8/10 Excellent! (49 reviews)
"Beautiful room, amazing view from the rooftop bar. Very helpful staff and easy to walk to amenities, including Anaconda market."

Reviewed on Jun 24, 2026

Hotel de Turistas Iquitos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz vacation package cost?
You'll find cheap prices on Expedia for your Santa Cruz getaway. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
January, February and April are great times to search for cheap Santa Cruz vacation packages. Opting to travel in quieter periods means you can typically find lower prices on flights and accommodations.
How many days is enough for Santa Cruz?
With a well-organized itinerary, you can easily hit the top Santa Cruz attractions in a handful of days. But if you'd like to discover hidden gems or take day trips, consider booking your Santa Cruz vacation for longer.
How to find the best Santa Cruz package deals?
Bagging a cheap Santa Cruz package deal is easy with Expedia. After you've entered your trip dates and destination under our "Packages" tab, set your budget, add some filters and browse what's available. You can personalize your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Santa Cruz package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll usually land a better deal than booking each component individually. And you'll still get the flexibility to create a customized Santa Cruz vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Santa Cruz?
If you've got your Santa Cruz vacation dates confirmed, book as early as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are ideal for impromptu escapes.
How to plan a trip to Santa Cruz?

  1. Choose the perfect time to travel: Your schedule, preferred season and the type of weather you enjoy can all impact your decision on when to go to Santa Cruz.
  2. Set a budget: Factor in costs such as food, flights and transportation when working out how much to set aside for your trip to Santa Cruz. Then, pick a hotel that matches your budget, whether that's an economical stay or a swankier getaway.
  3. Determine how many days away: Start by compiling a list of the attractions and activities you'd like to get to in Santa Cruz. Then, estimate how long you'll need at each, including any travel time.
  4. Combine your accommodations and airfare: After you've settled on your travel dates and duration, lock in the right Santa Cruz vacation package for you.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.