An aerial view of a town nestled in a valley with mountains in the background.

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Check prices for these dates

This weekend
Nov 6 - Nov 8
Next weekend
Nov 13 - Nov 15

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Our top choices for Santa Ana hotels

A covered outdoor seating area with modern furniture and arches.

1. Hilton Garden Inn Cusco

Hilton Garden Inn Cusco
3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (1,002 reviews)
"Nice hotel"
Canada
alan
The price is ￥19,419
￥21,361 total
Dec 3 - Dec 4
Hilton Garden Inn Cusco
A hotel room with a large bed, a flat-screen TV, a view of the city, and a wooden floor.

2. Mirador All Sur Cusco

Mirador All Sur Cusco
3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (2 reviews)
"Muy acogedor y limpio"
United States
Veronica Aide
The price is ￥3,545
￥3,545 total
Nov 3 - Nov 4
Mirador All Sur Cusco
A room with two wicker chairs, a small table with teapots, and a view of a desert landscape through large arched windows.

3. Loki Boutique Cusco

Loki Boutique Cusco
3.0 star property
Santa Ana
10.0 out of 10, Exceptional, (1 review)
"Beautiful rooms, delicious breakfast, very fun and social. I made new friends easily and the bed was sooo comfortable. I'll definitely recommend it. Great location, very nice building full of history. Loved it!"
Mexico
Jessica
The price is ￥11,789
￥11,789 total
Dec 3 - Dec 4
Loki Boutique Cusco
A courtyard with a fountain, outdoor seating, and a staircase leading to an upper level.

4. Tierra Viva Cusco Saphi

Tierra Viva Cusco Saphi
3.0 star property
Santa Ana
9.4 out of 10, Exceptional, (510 reviews)
"Charming hotel, friendly helpful staff. Great location. Generous buffet breakfast spread."
United States
David
The price is ￥9,104
￥10,188 total
Dec 2 - Dec 3
Tierra Viva Cusco Saphi
A room with a view of a cityscape and mountains through a window with a wooden chair in the foreground.

5. Anata Hostel

Anata Hostel
3.0 star property
Santa Ana
8.4 out of 10, Very good, (32 reviews)
"Great location, staff incredible!"
Canada
christiane
The price is ￥4,093
￥4,093 total
Nov 3 - Nov 4
Anata Hostel
A spacious room with a large window offering a mountain view, wooden furniture, and a swing chair.

6. Hotel El Mirador de Santa Ana

Hotel El Mirador de Santa Ana
2.5 star property
Santa Ana
9.0 out of 10, Wonderful, (7 reviews)
"I like the beds very comfy and how nice was the staff, very friendly and helpful. I didn’t like the stained shower curtain, no hair dryer or iron board on room."
United States
Claudia Guadalupe Loya
The price is ￥2,788
￥2,788 total
Nov 14 - Nov 15
Hotel El Mirador de Santa Ana
A two-story building with a stone facade, a central entrance with a door, and a staircase leading to the upper floor.

7. Inti Punku Cusco Centro Histórico Hotel

Inti Punku Cusco Centro Histórico Hotel
3.0 star property
Santa Ana
The price is ￥14,804
￥14,804 total
Nov 3 - Nov 4
Inti Punku Cusco Centro Histórico Hotel
A modern hotel room with two beds, a desk, a chair, a TV, and a wardrobe.

8. ZEVEN HOUSE - CUSCO APARTMENT

ZEVEN HOUSE - CUSCO APARTMENT
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (1 review)
"My wife and I are visiting Cusco from Dallas, Texas. We had a wonderful stay. The host spoke English and was very kind and helpful. He showed us how to operate the appliances. There was hot water in the shower, a gas stove, washing machine, refrigerator, TV with Netflix (big plus), and electric portable space heater (another big plus). The beds were very comfortable and warm. Wi-fi was fast and reliable. The place was quiet at night. Short walking distance to Orion grocery store. Definitely...
United States
Andrew
The price is ￥7,090
￥7,090 total
Nov 3 - Nov 4
ZEVEN HOUSE - CUSCO APARTMENT
A hotel room with two beds, a window with curtains, a nightstand, and a wall-mounted light.

9. Eco Bunnu Inn Santa Ana

Eco Bunnu Inn Santa Ana
2.0 star property
Santa Ana
9.4 out of 10, Exceptional, (3 reviews)
"Lovely staff and great room. Complimentary breakfast was delicious, would definitely recommend. Street noise but as to be expected."
Canada
Madeleine
The price is ￥2,917
￥2,917 total
Nov 8 - Nov 9
Eco Bunnu Inn Santa Ana
A hotel room with two beds, a balcony with a table and chairs, and a view of a building and hills.

10. valicha casa hotel

valicha casa hotel
3.0 star property
Santa Ana
8.4 out of 10, Very good, (7 reviews)
"Terrible stairs, I twisted my ankle, watch out for the last step. Very cold, no heating."
United States
HSINNENG
The price is ￥3,680
￥3,680 total
Nov 22 - Nov 23
valicha casa hotel
A house with a mural of a llama, a staircase, and a potted plant.

11. Casa del Valle

Casa del Valle
3.0 star property
Santa Ana
The price is ￥3,190
￥3,190 total
Nov 5 - Nov 6
Casa del Valle
A spacious lobby with a central staircase, multiple seating areas, and potted plants.

12. Hotel Mamasara

Hotel Mamasara
3.0 star property
Santa Ana
8.4 out of 10, Very good, (18 reviews)
"We only stayed one night as they were booked. Front desk helped us arrange a day trip to nearby ruins and sites like Salinas."
United States
Barbara A.
The price is ￥8,225
￥8,636 total
Nov 5 - Nov 6
Hotel Mamasara
A hotel room with two beds, a large window, and a ceiling fan.

13. HOSTAL LA RASA

HOSTAL LA RASA
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (3 reviews)
"Very kind host and supportive when our family was struggling acclimatizing to Cusco heights. Definitely plan on coming back here❤️"
United States
Alison
The price is ￥3,560
￥3,560 total
Nov 5 - Nov 6
HOSTAL LA RASA
An outdoor seating area with tables and chairs, a stone archway with colorful decorations, and potted plants.

14. Tucan Hostel

Tucan Hostel
2.0 star property
Santa Ana
8.2 out of 10, Very good, (15 reviews)
"Awesome place, close to many things. "
United States
MERCEDES
The price is ￥5,089
￥5,089 total
Nov 5 - Nov 6
Tucan Hostel
A modern interior with a staircase, wooden flooring, and colorful arches.

15. Centro by Casa Andina Cusco Saphi

Centro by Casa Andina Cusco Saphi
3.0 star property
Santa Ana
9.4 out of 10, Exceptional, (18 reviews)
"A pleasant place to visit Cuzco"
France
Michel
The price is ￥9,315
￥10,327 total
Dec 2 - Dec 3
Centro by Casa Andina Cusco Saphi
A spacious indoor area with a high ceiling, a staircase, a bench, and several potted plants.

16. Munay Ñusta Cusco

Munay Ñusta Cusco
3.0 star property
Santa Ana
8.4 out of 10, Very good, (5 reviews)
"Very nice property"
United States
Arthur
The price is ￥5,144
￥5,658 total
Nov 5 - Nov 6
Munay Ñusta Cusco
A compact kitchen with white walls, a refrigerator, a microwave, and a sink.

17. Casa Karmenka

Casa Karmenka
2.5 star property
Santa Ana
The price is ￥7,090
￥7,090 total
Nov 3 - Nov 4
Casa Karmenka
A hotel interior with a central atrium, multiple balconies with wrought iron railings, and a skylight.

18. Hotel Hacienda Cusco Centro Historico

Hotel Hacienda Cusco Centro Historico
4.0 star property
Cusco Historic Center, 0.3 km from Santa Ana
9.2 out of 10, Wonderful, (418 reviews)
"Very nice from beginning to end. Clean property, amazing service, always on time and accurate with our needs. Will visit again"
United States
Diana
The price is ￥11,855
￥17,373 total
Nov 25 - Nov 26
Hotel Hacienda Cusco Centro Historico
A courtyard with a red building, a wooden bench, and a hanging plant.

19. Tambo del Arriero Hotel Boutique

Tambo del Arriero Hotel Boutique
3.0 star property
Cusco Historic Center, 0.3 km from Santa Ana
9.4 out of 10, Exceptional, (1,001 reviews)
"Such a beautiful little hotel with gorgeous court yards. Good breakfast and coca tea to help with the altitude. The staff was very helpful and the rooms were lovely."
United States
Emily
The price is ￥13,273
￥13,273 total
Nov 5 - Nov 6
Tambo del Arriero Hotel Boutique
A stone-walled courtyard with multiple arches, a central fountain, and potted plants.

20. Wyndham Costa del Sol Cusco

Wyndham Costa del Sol Cusco
4.0 star property
Cusco Historic Center, 0.5 km from Santa Ana
9.4 out of 10, Exceptional, (1,235 reviews)
"Clean room, comfortable bed and great breakfast"
United States
Chrystal
The price is ￥18,655
￥20,521 total
Dec 2 - Dec 3
Wyndham Costa del Sol Cusco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Ana

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A covered outdoor seating area with modern furniture and arches.
Hilton Garden Inn Cusco
3.5 star property
9.2
Wonderful
1,002 reviews
View
A courtyard with a fountain, outdoor seating, and a staircase leading to an upper level.
Tierra Viva Cusco Saphi
3.0 star property
9.4
Exceptional
510 reviews
View
A modern interior with a staircase, wooden flooring, and colorful arches.
Centro by Casa Andina Cusco Saphi
3.0 star property
9.4
Exceptional
18 reviews
View
A spacious room with a large window offering a mountain view, wooden furniture, and a swing chair.
Hotel El Mirador de Santa Ana
2.5 star property
9.0
Wonderful
7 reviews
View
A room with a view of a cityscape and mountains through a window with a wooden chair in the foreground.
Anata Hostel
3.0 star property
8.4
Very good
32 reviews
View

Hotels recommended for families in Santa Ana

A covered outdoor seating area with modern furniture and arches.

Hilton Garden Inn Cusco

Hilton Garden Inn Cusco
3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (1,002)
The price is ￥19,419
￥21,361 total
Dec 3 - Dec 4
Hilton Garden Inn Cusco

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
A historic cathedral with two bell towers and a large dome.

Cusco Historic Center

Explore museums like Museo de Arte Precolombino and savor fusion and neo-Andean cuisine at local restaurants. Stroll through the artisan-filled San Blas neighborhood for a picturesque shopping experience.

A narrow cobblestone street flanked by white buildings with blue shutters and wrought iron balconies.

San Blas

Take a walk through the heart of Cusco’s artisan district, one of the city’s most beguiling and lively areas.

A cityscape with red-tiled roofs, a prominent church, and distant mountains.
Photo by AdventureJ
Open Photo by AdventureJ

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Museo de Arte Precolombino and Plaza Sán Cristobal.

A person climbing a stone wall with a backpack.
Photo by Wicked Walkabout
Open Photo by Wicked Walkabout

Santiago

If you're spending some time in Santiago, Santiago Plaza and "El Molino I" Shopping Center are top sights worth seeing.

Terraced fields, mountains, and a clear sky.

Coripata

When in Coripata, you can plan a visit to Centro Qosqo de Arte Nativo and Coricancha, some noteworthy sights in the nearby area.

Top Santa Ana Hotel Reviews

Kantu Hotel

Kantu Hotel

10/10 Excellent
"A great hotel 5 minutes from the main Plaza. Excellent breakfast and restaurant. They provide a packed lunch if you are going for day tours which usually leave very early. The rooms are spotless and there's always plenty of hot water. The staff were amazing. Friendly and helpful. We used their recommended tour agent Kati and she was wonderful . Highly recommended hotel I can't say enough good things about Casa Kantu"
Mark 9-night trip
Posted 10 hours ago
Kantu Hotel

Frequently asked questions

What is Santa Ana like?
Travelers to Cusco's Santa Ana neighborhood will be sure to enjoy a stay in this neighborhood.
What's the best accommodation in Santa Ana?
Based on our traveler data, Hilton Garden Inn Cusco is one of the top choices for your stay in Santa Ana. This hotel is a short 11-minute walk from Plaza de Armas, and it offers 2 bars and a restaurant.
How many hotels should I expect to find in the Santa Ana area?
If you're searching for places to stay in Cusco, Expedia has something to meet your needs with 47 Santa Ana hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, go to https://www.expedia.com/service/.
What can I see and do in this Cusco neighborhood?
A few places to visit in the area around Santa Ana include Museo Irq'i Yachay, Museo de Plantas Sagradas Magicas y Medicinales, and San Francisco Church Museum and Catacombs. Museum of Contemporary Art and ChocoMuseum are also worth a visit when you're out sightseeing in Cusco.