Find hotels in San Cosme y Damian from ￥9,446

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Stay near popular San Cosme y Damian attractions

Buenaventura Suarez Planetarium

You can spend time browsing the exhibits at Buenaventura Suarez Planetarium during your travels in San Cosme y Damian. Take in the museums while you're in the area.
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Guarani Jesuit Ruins of San Cosme and San Damián

Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area.
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Top San Cosme y Damian Hotel Reviews

More cheap stays in San Cosme y Damian

Puesta del Sol by Nobile

Puesta del Sol by Nobile

14 de Mayo 44 Esq. Av. Francia Encarnacion Itapua
The price is ￥8,587 per night from Jan 4 to Jan 5
￥8,587
￥9,446 total
Jan 4 - Jan 5, 2026
includes taxes & fees
8.6/10 Excellent! (48 reviews)

Frequently asked questions

If I need to cancel my hotel reservation in San Cosme y Damian, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in San Cosme y Damian.
Where can I learn more about changing or cancelling my trip to San Cosme y Damian?
To access more information about changing or cancelling your trip to San Cosme y Damian, click here.
What is the best accommodation for staying close to Silvio Pettirossi International Airport (ASU)?
Bourbon Conmebol Asuncion Convention Hotel is a popular 4-star hotel featuring free breakfast and a restaurant. It's located a short 1.4 mi (2.3 km) from Silvio Pettirossi Intl. Airport. Other options close to the airport include Dazzler by Wyndham Asuncion and Esplendor by Wyndham Asunción.
What are the top places to visit in San Cosme y Damian?
A couple of favorite places to visit are Buenaventura Suarez Planetarium and Guarani Jesuit Ruins of San Cosme and San Damián. Check out what more to see and do in Expedia's San Cosme y Damian guide.
What's the weather like in San Cosme y Damian?
The hottest months are usually January and February with an average temp of 80°F, while the coldest months are July and June with an average of 62°F. The rainiest months in San Cosme y Damian are October, November, May, and April, with each month seeing an average of 8 inches of rainfall.