A coastal town with colorful buildings, a mountain range in the background, and boats in the water.

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Check availability on Samos Luxury Hotels

Tonight
Oct 6 - Oct 7
Tomorrow
Oct 7 - Oct 8
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Samos luxury hotels

A modern resort with a central pool, lounge areas, and mountain views.
A beachside resort with outdoor seating areas, umbrellas, and a view of the sea.
A spa area with two massage tables, a stone floor, and a bamboo partition.
A beachside lounge area with outdoor seating, a large umbrella, and a view of the sea.

1. Casa Cook Samos

Casa Cook Samos
Samos
  • Beachfront luxury meets spa indulgence at Casa Cook Samos, where Mediterranean elegance awaits.
￥33,301
￥39,138 total
includes taxes & fees
Oct 21 - Oct 22
Casa Cook Samos
A row of wooden beach umbrellas with white cushions on a sandy beach, overlooking the sea.
A covered outdoor seating area with wooden flooring, white cushioned chairs, and tables.
A serene outdoor setting with a pool, a person in a white dress, and a view of the sea.
A modern bedroom with a bed, bedside tables, a desk, and a view of the sea.

2. Proteas Blu Resort - Adults Only

Proteas Blu Resort - Adults Only
Samos
  • Private beachfront luxury meets seaside serenity at this adults-only Samos resort offering spa indulgences and ocean-view dining.
￥24,434
￥29,432 total
includes taxes & fees
Oct 11 - Oct 12
Proteas Blu Resort - Adults Only
An infinity pool with lounge chairs and a view of a coastal town.
A modern outdoor seating area with a view of a coastal town and mountains.
A bar area with stools, a counter, and bottles.
A modern multi-story building with a landscaped courtyard, featuring a mix of flat and sloped roofs, and a variety of plants and trees.

3. Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)

Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
Samos
￥24,746
￥29,766 total
includes taxes & fees
Oct 23 - Oct 24
Nirema Hotel & Spa Samos - MGallery Collection (opening Q3 2026)
A pool area with lounge chairs and umbrellas, surrounded by stone walls and greenery.
A boutique hotel entrance with a stone pathway, wooden gates, and potted plants.
A modern reception desk with a wooden surface, a computer, and a vase with flowers. There are chairs and a staircase in the background.
A wooden deck with lounge chairs and a pool.

4. Doryssa Boutique Hotel

Doryssa Boutique Hotel
Samos
￥20,230
￥23,938 total
includes taxes & fees
Oct 7 - Oct 8
Doryssa Boutique Hotel
View all properties

Top Samos Hotel Reviews

Doryssa Seaside Resort

Doryssa Seaside Resort

10/10 Excellent
"A gorgeous property, great location, courteous staff… would def stay there again!! Perfect room!!😊"
Athanasios 2-night trip
Posted 10 days ago
Doryssa Seaside Resort

Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Samos?
Arrange a flight into Samos (SMI-Samos Intl.) Airport or Ikaria Island (JIK) Airport, and then treat yourself to a stay at one of 6 luxurious hotels. Samos has some interesting things to see and do including Port of Samos and Samos Port, so you might want to take in the local sights during your visit.
What's the best luxury hotel in Samos?
Casa Cook Samos is a luxury hotel with a beachfront restaurant and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Proteas Blu Resort - Adults Only and Doryssa Seaside Resort are other upscale choices for your stay.
How many luxury hotels will I find in Samos?
Lie in the lap of luxury during your getaway to Samos in one of Expedia's 6 luxury hotels.
When can I expect good weather in Samos?
Planning for the weather is an important factor for making your trip to Samos a success, especially when you're splurging. The hottest months are usually August and July with an average temp of 77°F, while the coldest months are January and February with an average of 55°F. Average annual precipitation for Samos is 33 inches.
What's there to see and do in Samos?
Enjoy Samos and visit Port of Samos, Samos Port, and Gagou Beach. If you have extra time while you're in the area, you might want to see Psili Amos Beach and Glicorisa Beach.