The Best Hotels Closest to Regional Medical Center in San Jose for 2026

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Our top choices for Regional Medical Center hotels

An outdoor seating area with sofas, tables, and a fire feature.

A modern bar area with a curved counter, stainless steel appliances, and contemporary bar stools.

A modern lounge area with comfortable seating, large windows, and a view of the outdoors.

A Courtyard Marriott hotel with a modern glass facade, multiple floors, and a landscaped courtyard with trees and a pool.

1. Courtyard by Marriott San Jose North/Silicon Valley

North San Jose, 11.1 km from Regional Medical Center

Sandie

￥20,013

￥23,451 total

includes taxes & fees

Oct 30 - Oct 31

A hotel room with a bed, a desk with a computer, a chair, a sofa, and a large window offering a view.

A modern lobby with seating arrangements, a large window with a cityscape view, and a decorative wall piece.

A modern hotel lobby with wooden furniture, a bar area, and a television mounted on the wall.

A modern hotel lobby with a reception desk, seating area, and a dining section.

2. Hyatt Place San Jose/Downtown

Downtown San Jose, 5.2 km from Regional Medical Center

Juan

￥21,333

￥25,262 total

includes taxes & fees

Nov 1 - Nov 2

A modern house with a balcony, a dining area, and a kitchen.

A modern interior with a seating area, tables, and a large window overlooking a street.

A reception desk with a 'HELLO San Jose' sign, a minibar with snacks and beverages, and a 'MARRIOTT BONVOY' sign on the wall.

A modern indoor space with a large dining area, seating arrangements, and large windows offering views of the outside.

3. Towneplace Suites By Marriott San Jose Downtown

5.9 km from Regional Medical Center

David E

￥18,062

￥21,461 total

includes taxes & fees

Oct 30 - Oct 31

An outdoor seating area with a fire feature, a glass wall, and a view of the street.

A modern hotel room with a kitchenette, a dining area, a large bed, and a view of the cityscape.

A modern hotel room with a large window, a sofa, a bedside table with a lamp, and a bed.

A modern hotel with a flat facade, multiple balconies, and a central entrance.

4. Hyatt House San Jose Airport

Trimble Business Area, 6.3 km from Regional Medical Center

Rose

￥18,646

￥21,943 total

includes taxes & fees

Oct 25 - Oct 26

A swimming pool with four lounge chairs and a view of trees through large windows.

A gym with treadmills, elliptical machines, and weight benches.

A conference room with a long table, green chairs, and framed artwork on the wall.

A hotel room with two beds, a desk, a chair, a TV, and a large window.

5. Holiday Inn Express & Suites San Jose Airport by IHG

Trimble Business Area, 6.3 km from Regional Medical Center

Marissa

￥19,278

￥22,677 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel with large glass windows, a well-lit lobby, and a landscaped garden area.

A modern hotel lobby with seating areas, a bar, and a television screen.

A modern outdoor seating area with a fire pit, cushioned chairs, and a railing.

A modern kitchen with a marble island, bar stools, and various appliances.

6. Hilton Garden Inn San Jose Airport

Rosemary, 5.1 km from Regional Medical Center

Hyunchae

￥16,548

￥19,504 total

includes taxes & fees

Oct 30 - Oct 31

A modern lobby with a seating area, a bar, and a fireplace.

A modern restaurant with high tables and chairs, large windows, and a bar area with bottles and a TV screen.

An outdoor patio with a grill, seating area, and a table with chairs.

A hotel room with a bed, a desk, a TV, a sofa, and a window with a view.

7. Residence Inn by Marriott San Jose Airport

Rosemary, 5.7 km from Regional Medical Center

Kristel Joyce

￥22,110

￥25,968 total

includes taxes & fees

Oct 23 - Oct 24

A spacious hotel lobby with a grand chandelier, a staircase, and red seating along the walls.

A hotel room with a large bed, a wooden headboard, two bedside tables, and a small round table.

A room with a large window, a flat-screen TV, a wooden cabinet, and a blue patterned carpet.

An outdoor patio area with wooden benches and tables, surrounded by trees and a wooden fence.

8. Four Points by Sheraton San Jose Downtown

Downtown San Jose, 4.8 km from Regional Medical Center

Greg

￥19,365

￥23,112 total

includes taxes & fees

Nov 8 - Nov 9

A building facade with ornate architectural details, including a large arched window and decorative stonework.

A large hall with rows of chairs and a central aisle, a glass ceiling, and columns.

A modern bathroom with a large bathtub, candles, and a towel rack.

A spacious lobby with a long bar, comfortable seating, and large windows.

9. The Westin San Jose

Downtown San Jose, 4.9 km from Regional Medical Center

Cheryl

￥22,368

￥26,974 total

includes taxes & fees

Oct 31 - Nov 1

A modern kitchen with a long island, bar stools, and pendant lighting.

A modern hotel lobby with a round table, two chairs, a pendant light, a painting, a reception area, and a large window.

A spacious hotel lobby with a large dining area, a staircase, and a view into a kitchen area.

A reception area with a wooden reception desk, a decorative wall piece, and a vending machine.

10. Fairfield Inn & Suites by Marriott San Jose Airport

Rosemary, 6 km from Regional Medical Center

Gonzalo

￥17,938

￥21,120 total

includes taxes & fees

Oct 30 - Oct 31

A modern lobby with a flat-screen TV, a fireplace, comfortable seating, and a reception desk.

A modern conference room with a long table, several chairs, a blue sofa, and a large screen.

A hotel room with two beds, a desk, a TV, and a window with a view.

A modern living room with a flat-screen TV, built-in shelving, a fireplace, and a sofa.

11. La Quinta Inn & Suites by Wyndham San Jose Airport-Downtown

4.6 km from Regional Medical Center

Marvin

￥16,813

￥19,504 total

includes taxes & fees

Oct 25 - Oct 26

A modern Hyatt Place hotel with a glass facade, a covered entrance, and a landscaped driveway.

A modern bar area with a wooden counter, bar stools, and a variety of liquor bottles.

A hotel room with a wooden desk, two beds, a sofa, a TV, and a large window.

A room with a mirrored wall, wooden paneling, and two sofas facing a television.

12. Hyatt Place San Jose Airport

Trimble Business Area, 6.4 km from Regional Medical Center

Kenneth

￥18,646

￥21,943 total

includes taxes & fees

Nov 13 - Nov 14

A hotel room with a large bed, a desk, a TV, and a view of the city through large windows.

A modern hotel lobby with a large seating area, multiple TV screens, and a colorful carpet.

A modern hotel lobby with a sectional sofa, a round wooden coffee table, and a large wall-mounted TV.

A patio area with a grill, seating, and a table with chairs.

13. SpringHill Suites by Marriott San Jose Airport

Rosemary, 5.7 km from Regional Medical Center

Kelton

￥21,356

￥25,092 total

includes taxes & fees

Oct 23 - Oct 24

A Courtyard by Marriott hotel with a covered entrance, multiple balconies, and palm trees in the background.

A modern hotel lobby with a large sports game on the wall, comfortable seating, and a view of the dining area.

A modern lounge area with sofas, armchairs, and a coffee table.

A multi-story residential building with balconies, outdoor seating, and a landscaped garden area.

14. Courtyard by Marriott Milpitas Silicon Valley

6.6 km from Regional Medical Center

Rebecca

￥20,069

￥22,941 total

includes taxes & fees

Oct 30 - Oct 31

A modern hotel lobby with a dining area, seating arrangements, and a large artwork on the wall.

A spacious dining area with wooden tables and chairs, a high ceiling with recessed lighting, and clear exit signs.

A buffet with various food items, including omelets and cheese.

A spacious indoor area with a large table and chairs, a sofa, and a staircase leading to another level.

15. Holiday Inn Express & Suites San Jose Silicon Valley by IHG

South San Jose, 7.4 km from Regional Medical Center

Alma

￥23,387

￥27,411 total

includes taxes & fees

Oct 25 - Oct 26

A breakfast area with a counter, coffee machines, and seating.

A hotel building with a sign that reads "Quality Inn by Choice Hotels."

A hotel room with a dark leather sofa, a wooden coffee table, a bed with a green blanket, a desk with a chair, and a wardrobe.

A hotel reception area with a reception desk, framed awards, a clock, and a view of the outside through the glass door.

16. Quality Inn San Jose Airport/Silicon Valley

Berryessa, 6.7 km from Regional Medical Center

Tammy

￥15,502

￥18,086 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor seating area with wicker furniture and a central fire pit.

A modern kitchen with a central island, wooden ceiling, and pendant lighting.

A modern bar area with a long counter, bar stools, and pendant lighting.

A spacious lobby with a high ceiling, a central seating area with sofas and chairs, a long wooden table, and a staircase leading to an upper level.

17. Holiday Inn San Jose - Silicon Valley by IHG

Rosemary, 5.2 km from Regional Medical Center

Estrella

￥19,436

￥22,823 total

includes taxes & fees

Oct 30 - Oct 31

An outdoor patio area with a stone wall, a black fire pit, wicker furniture, and a view of the sky.

A modern lobby with leather sofas, a stone accent wall, a fireplace, and potted plants.

A modern restaurant with a bar area, seating arrangements, and a large window offering a view.

A hotel room with a desk, two beds, a large mirror, and a view of the outdoors.

18. SpringHill Suites by Marriott Milpitas Silicon Valley

11.1 km from Regional Medical Center

Aisha

￥17,787

￥20,277 total

includes taxes & fees

Nov 14 - Nov 15

A hotel room with a large bed, a sofa, a coffee table, and two windows with blinds.

A modern hotel entrance with a covered driveway, stone pillars, and a clear sign indicating the time of day.

An outdoor patio with wicker furniture, a table with a vase, and a large umbrella.

A swimming pool with tiled edges, surrounded by lounge chairs and umbrellas, with palm trees and a clear sky in the background.

19. Best Western University Inn Santa Clara

9.4 km from Regional Medical Center

Gary

￥16,926

￥19,244 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel lobby with a curved sofa, a glass coffee table, and a fireplace.

A hotel lobby with seating areas, a bar, and a kitchenette.

An outdoor patio area with wicker furniture, including sofas and chairs, and a coffee table with a pitcher and glasses.

A modern hotel room with a sofa, ottoman, desk, and lamp.

20. Sonesta Select San Jose Airport

Rosemary, 6.1 km from Regional Medical Center

Aimee

￥18,330

￥21,734 total

includes taxes & fees

Nov 13 - Nov 14

View all properties

Compare popular hotels close to Regional Medical Center

Property	Star rating	Guest rating
Courtyard by Marriott San Jose North/Silicon Valley	9.2 Wonderful 780 reviews	View
Hyatt Place San Jose/Downtown	9.0 Wonderful 1,622 reviews	View
Towneplace Suites By Marriott San Jose Downtown	9.6 Exceptional 550 reviews	View
Hyatt House San Jose Airport	9.0 Wonderful 1,009 reviews	View
Holiday Inn Express & Suites San Jose Airport by IHG	8.8 Excellent 1,344 reviews	View

Hotels recommended for families near Regional Medical Center

Hilton Garden Inn San Jose Airport

Rosemary

￥16,548

￥19,504 total

includes taxes & fees

Oct 30 - Oct 31

La Quinta Inn & Suites by Wyndham San Jose Airport-Downtown

Hyde Park

￥16,813

￥19,504 total

includes taxes & fees

Oct 25 - Oct 26

Holiday Inn San Jose - Silicon Valley by IHG

Rosemary

￥19,436

￥22,823 total

includes taxes & fees

Oct 30 - Oct 31

A courtyard with a table and chairs, surrounded by greenery and a glass wall.

A modern cafe with a central island, seating area, and a large window providing a view.

A hotel room with two beds, a wooden headboard, a nightstand with a phone, and a lamp.

A modern living room with a sectional sofa, a small ottoman, a wooden coffee table, and a dining area with chairs.

Country Inn & Suites by Radisson, San Jose International Airport, CA

Rosemary

￥15,271

￥17,991 total

includes taxes & fees

Nov 14 - Nov 15

A spacious lobby with a central bar area, multiple seating arrangements, and a modern chandelier.

A conference room with rows of tables and chairs, a stage with a screen, and chandeliers.

A hotel room with a large bed, a bench, a chair, a desk, a TV, and a window with a city view.

A gym with treadmills, stationary bikes, and exercise balls.

Signia by Hilton San Jose

Downtown San Jose

￥25,915

￥30,587 total

includes taxes & fees

Oct 30 - Oct 31

Sonesta Select San Jose Airport

Rosemary

￥18,330

￥21,734 total

includes taxes & fees

Nov 13 - Nov 14

A modern dining area with multiple tables and chairs, a central bar, and a fireplace.

A modern kitchen with a built-in oven, a coffee maker, and a sink.

A modern hotel building with a prominent sign for Hampton Inn & Suites by Hilton.

A modern lounge area with a sofa, chairs, a bar, and a patterned rug.

Hampton Inn & Suites San Jose Airport

North San Jose

￥17,363

￥20,452 total

includes taxes & fees

Nov 13 - Nov 14

An outdoor patio area with a fire pit, seating, and string lights.

A gym with treadmills, a weight machine, and exercise balls.

A reception area with a wooden reception desk, a seating area with chairs, and a wall with a collage of images.

A spacious hotel lobby with a high ceiling, a reception desk, a dining area, and a kitchen visible in the background.

Sonesta ES Suites San Jose Airport

Trimble Business Area

￥21,175

￥24,881 total

includes taxes & fees

Nov 1 - Nov 2

Top Regional Medical Center Hotel Reviews

The Westin San Jose

10/10 Excellent

"This place worked out great for our stay for an event at SAP center. We were able to walk to and from the event. Nice clean property."

Marbella Lane - 3BR UpprLvl | DTWN SJ | Ldry + P

10/10 Excellent

"Clean rooms, great communication from the host and excellent location"

Central Mini putt getaway

10/10 Excellent

"Excellent platform for all communications. Host was readily available for questions and had the answers!"

Beauty Home 3Br/2Bath Nearby Downtown in San Jose

10/10 Excellent

"Nice clean place, great communication with Host. Would definitely stay here again."

Charming 3-bedroom Guest house in enchanting San Jose with AC

10/10 Excellent

"Ok"

NewLuxHome!PoolTable!HotTub!Heart of Downtown SJ

10/10 Excellent

"I would do it again!"

@ Marbella Lane - 2BR Cozy LwrLvl in DTWN SJ

10/10 Excellent

"Nice neighborhood, clean, pet-friendly, and a great location not far from SAP Center & downtown! #Neighborhood #Location #Pets"

@ Marbella Lane - 2BR LwrLvl | DTWN SJ | Ldry + P

8/10 Good

"The overall experience was ok but the check-in process was a struggle. We had to provide the same information multiple times before receiving the code to enter the property. After a long trip, we arrived and we were standing at the door waiting for the code despite we arrived later than the check-in time.We were advised that some repairs need to be done while we are in the property which of course was not convenient. One more thing, we were four guests and there were only 3 coffee cups in the kitchen!"

@ Marbella Lane - MiniGuest House | DTWN SJ | Parking

10/10 Excellent

"Very Nice. Waiting for refund for 28day Extension! "

Frequently asked questions

What's the area like around Regional Medical Center?

Regional Medical Center is located in San Jose. You'll find 477 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay near Regional Medical Center?

Sonesta Select San Jose Airport is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. It's located 3.8 mi (6.1 km) from Regional Medical Center. Other good choices within 5 miles include The Westin San Jose and Hyatt Place San Jose/Downtown.

How many hotels will I find near Regional Medical Center?

Expedia has 477 hotels and other accommodations a few miles from Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Regional Medical Center, will I receive a refund?

Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to review top deals close to Regional Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Regional Medical Center?

For more information about rescheduling or cancelling your stay near Regional Medical Center, go to https://www.expedia.com/service/.

What can I see and do near Regional Medical Center?

The Tech Interactive, History Park, and San Jose Museum of Art feature a variety of fascinating exhibits to see while you're in town. California Theater, Mission Santa Clara de Asis, and Electric Light Tower are notable landmarks to explore if you're in the area. You can check out the local talent at San Jose Civic Auditorium, Hammer Theatre, and Montgomery Theater.

How can I get to Regional Medical Center?

You can walk to nearby metro stations including Alum Rock Station, McKee Station, and Penitencia Creek Station. If you'd like to venture farther outside of the area, you may want a car rental for your journey.

Find hotels near Regional Medical Center, San Jose from ￥18,086

Change your mind

Treat yourself

Be picky

Check prices for these dates

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Property class

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Our top choices for Regional Medical Center hotels

1. Courtyard by Marriott San Jose North/Silicon Valley

2. Hyatt Place San Jose/Downtown

3. Towneplace Suites By Marriott San Jose Downtown

4. Hyatt House San Jose Airport

5. Holiday Inn Express & Suites San Jose Airport by IHG

6. Hilton Garden Inn San Jose Airport

7. Residence Inn by Marriott San Jose Airport

8. Four Points by Sheraton San Jose Downtown

9. The Westin San Jose

10. Fairfield Inn & Suites by Marriott San Jose Airport

11. La Quinta Inn & Suites by Wyndham San Jose Airport-Downtown

12. Hyatt Place San Jose Airport

13. SpringHill Suites by Marriott San Jose Airport

14. Courtyard by Marriott Milpitas Silicon Valley

15. Holiday Inn Express & Suites San Jose Silicon Valley by IHG

16. Quality Inn San Jose Airport/Silicon Valley

17. Holiday Inn San Jose - Silicon Valley by IHG

18. SpringHill Suites by Marriott Milpitas Silicon Valley

19. Best Western University Inn Santa Clara

20. Sonesta Select San Jose Airport

Compare popular hotels close to Regional Medical Center

Hotels recommended for families near Regional Medical Center

Hilton Garden Inn San Jose Airport

La Quinta Inn & Suites by Wyndham San Jose Airport-Downtown

Holiday Inn San Jose - Silicon Valley by IHG

Country Inn & Suites by Radisson, San Jose International Airport, CA

Signia by Hilton San Jose

Sonesta Select San Jose Airport

Hampton Inn & Suites San Jose Airport

Sonesta ES Suites San Jose Airport

Top Regional Medical Center Hotel Reviews

The Westin San Jose

Marbella Lane - 3BR UpprLvl | DTWN SJ | Ldry + P

Central Mini putt getaway

Beauty Home 3Br/2Bath Nearby Downtown in San Jose

Charming 3-bedroom Guest house in enchanting San Jose with AC

NewLuxHome!PoolTable!HotTub!Heart of Downtown SJ

@ Marbella Lane - 2BR Cozy LwrLvl in DTWN SJ

@ Marbella Lane - 2BR LwrLvl | DTWN SJ | Ldry + P

@ Marbella Lane - MiniGuest House | DTWN SJ | Parking

Frequently asked questions