Find hotels near Poplar Bluff Regional Medical Center, Poplar Bluff from ¥9,959

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Our top choices for Poplar Bluff Regional Medical Center hotels

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
0.2 km from Poplar Bluff Regional Medical Center
9.4 out of 10, Exceptional, (855)
"Very clean, great check in"
United States
Teresa
The price is ¥16,050
¥18,133 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Fairfield Inn & Suites by Marriott Poplar Bluff

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
1.3 km from Poplar Bluff Regional Medical Center
9.4 out of 10, Exceptional, (796)
"Staff was kind and provided a lot of information during check out."
United States
Shea
The price is ¥15,483
¥17,337 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hampton Inn Poplar Bluff

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
1.8 km from Poplar Bluff Regional Medical Center
9.2 out of 10, Wonderful, (965)
"Nice room helpful staff. "
United States
Deborah
The price is ¥14,547
¥16,432 total
includes taxes & fees
Dec 22 - Dec 23
Drury Inn & Suites Poplar Bluff

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
1 km from Poplar Bluff Regional Medical Center
8.8 out of 10, Excellent, (703)
"Amazing place"
United States
Mladen
The price is ¥17,025
¥19,233 total
includes taxes & fees
Dec 22 - Dec 23
Holiday Inn Poplar Bluff by IHG

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
2.1 km from Poplar Bluff Regional Medical Center
7.8 out of 10, Good, (1000)
"Love the updated rooms and the vending area."
United States
Kathi
The price is ¥11,763
¥12,407 total
includes taxes & fees
Dec 21 - Dec 22
Motel 6 Poplar Bluff, MO

Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
1.6 km from Poplar Bluff Regional Medical Center
7.8 out of 10, Good, (399)
"it was a nice stay, room was a little warm, thermostat may need changing out. Other than that it was great. "
United States
Jim
The price is ¥14,055
¥15,879 total
includes taxes & fees
Dec 25 - Dec 26
Comfort Inn Poplar Bluff North

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
1.1 km from Poplar Bluff Regional Medical Center
6.6 out of 10, (623)
"The lady at the front was very nice. "
United States
Travis
The price is ¥8,814
¥9,959 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Super 8 by Wyndham Poplar Bluff Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Poplar Bluff Regional Medical Center Hotel Reviews

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Frequently asked questions

What's the area like around Poplar Bluff Regional Medical Center?
Poplar Bluff Regional Medical Center is located in Poplar Bluff. Travelers like this family-friendly area for its restaurants. You'll find 18 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Poplar Bluff Regional Medical Center?
Adjacent to Poplar Bluff Regional Medical Center, Fairfield Inn & Suites by Marriott Poplar Bluff is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. Other good options close by include Holiday Inn Poplar Bluff by IHG and Hampton Inn Poplar Bluff.
How many hotels can I expect to find close to Poplar Bluff Regional Medical Center?
Expedia has 18 hotels and other accommodations a few miles from Poplar Bluff Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Poplar Bluff Regional Medical Center, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the "fully refundable" filter to get the best deals near Poplar Bluff Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Poplar Bluff Regional Medical Center?
For additional details about updating your stay near Poplar Bluff Regional Medical Center or cancelling it, go to https://www.expedia.com/service/.
What can I see and do near Poplar Bluff Regional Medical Center?
You'll want to browse the exhibits at Margaret Harwell Art Museum and Mo-Ark Regional Railroad Museum. You might plan a visit to Black River Coliseum or Ozark Ridge Golf Course while you're in the area. A visit to North Main Street Historic District is worth the trip when you're visiting.