Photo by Corey Dargan

Orangeburg Vacation Rentals

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Our top choices for Orangeburg vacation rentals

Nene’s Cozy Corner

Nene’s Cozy Corner
Orangeburg
7.8 out of 10, Good, (14)
"Overall, our stay was good. We loved having the comfort and space. It was quiet and still convenient to the places we needed to visit. "
United States
Natasia W.
Nene’s Cozy Corner

Secluded Cabin Retreat with Hot Tub, for Family Get Away

Secluded Cabin Retreat with Hot Tub, for Family Get Away
orangeburg
9.8 out of 10, Exceptional, (149)
"Traveling to the area for a family wedding and the cabin was the perfect place to stay to be close to the festivities!"
United States
Kristine G.
Secluded Cabin Retreat with Hot Tub, for Family Get Away

2 Mi to SC State & Claflin: Townhome w/ Patio!

2 Mi to SC State & Claflin: Townhome w/ Patio!
3.0 star property
Orangeburg
2 Mi to SC State & Claflin: Townhome w/ Patio!

Fully furnished cozy 2-bedroom apartment on quiet lot in Orangeburg, SC

Fully furnished cozy 2-bedroom apartment on quiet lot in Orangeburg, SC
Orangeburg
Fully furnished cozy 2-bedroom apartment on quiet lot in Orangeburg, SC

Your 4 bedroom 3 full bathroom Orangeburg Oasis awaits!!!!

Your 4 bedroom 3 full bathroom Orangeburg Oasis awaits!!!!
Orangeburg
Your 4 bedroom 3 full bathroom Orangeburg Oasis awaits!!!!

Walk to SC State University & Claflin: Cozy Home

Walk to SC State University & Claflin: Cozy Home
2.0 star property
Orangeburg
Walk to SC State University & Claflin: Cozy Home

Centally located w/ coffee bar, theatre/gameroom

Centally located w/ coffee bar, theatre/gameroom
Orangeburg
10.0 out of 10, Exceptional, (18)
"Charming house that was perfect for our group of six. "
United States
Grant S.
Centally located w/ coffee bar, theatre/gameroom

Secluded Retreat With hot tub ideal to fish and relax on private pond

Secluded Retreat With hot tub ideal to fish and relax on private pond
Orangeburg
9.8 out of 10, Exceptional, (37)
"Came here with friends, it was a nice house with great view! Would come again!!!"
United States
Leonardo M.
Secluded Retreat With hot tub ideal to fish and relax on private pond

RayneBow Royalty

RayneBow Royalty
2.0 star property
Orangeburg
RayneBow Royalty

3 bedroom Near hospital, college’s and shopping!

3 bedroom Near hospital, college’s and shopping!
Orangeburg
3 bedroom Near hospital, college’s and shopping!

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6
2.0 star property
Summerton
9.6 out of 10, Exceptional, (15)
"Convenient location, enjoyed fishing from dock in front too. Just right for quick fishing trip."
United States
Chris R.
The price is ¥11,195
¥24,508 total
includes taxes & fees
Dec 22 - Dec 23
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Pet friendly country cottage with large fenced-in yard & horses on property

Pet friendly country cottage with large fenced-in yard & horses on property
Holly Hill
10.0 out of 10, Exceptional, (123)
"Wonderful experience! So quiet, beautiful surroundings & very helpful hosts! "
United States
Jen S.
The price is ¥17,529
¥32,085 total
includes taxes & fees
Dec 15 - Dec 16
Pet friendly country cottage with large fenced-in yard & horses on property

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Summerton
10.0 out of 10, Exceptional, (162)
"Always enjoy our stay"
United States
Tabitha K.
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Lake Marion Lakehouse with 180° lake view

Lake Marion Lakehouse with 180° lake view
Elloree
10.0 out of 10, Exceptional, (74)
"Overall very relaxing and quiet. Host were very accommodating with check in and out. "
United States
Anonymous traveler
Lake Marion Lakehouse with 180° lake view

A Charming Country Cottage Nestled in the Woods

A Charming Country Cottage Nestled in the Woods
Hopkins
10.0 out of 10, Exceptional, (70)
"Awesome property close to Congaree National Park with a lot of unique and nice touches. Great communication, check in and check out."
United States
Tim G.
A Charming Country Cottage Nestled in the Woods

Wyndham Vacation Resorts Lake Marion

Wyndham Vacation Resorts Lake Marion
4.0 star property
Santee
9.2 out of 10, Wonderful, (21)
"Excellent "
United States
John
Wyndham Vacation Resorts Lake Marion

Lake Marion - Majestic Big Water View!

Lake Marion - Majestic Big Water View!
Santee
10.0 out of 10, Exceptional, (9)
"Very very nice. Would recommend it for a great stay. "
United States
susan l.
Lake Marion - Majestic Big Water View!

Country Resting Spot just off I95. 12 miles west on hwy 6.

Country Resting Spot just off I95. 12 miles west on hwy 6.
Elloree
9.4 out of 10, Exceptional, (21)
"Great place for our family to stop on our way to Florida. It had ample parking, pet friendly, and very comfortable country retreat! "
United States
Jackie M.
The price is ¥18,697
¥28,018 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Country Resting Spot just off I95. 12 miles west on hwy 6.

Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Rimini
8.2 out of 10, Very Good, (14)
"Wish bathroom was closer but jt"
United States
Sharon W.
The price is ¥11,895
¥20,627 total
includes taxes & fees
Dec 17 - Dec 18
Cozy Camping Cabin on Lake Marion near Congaree Nat Park

Cottage Tree House B&B

Cottage Tree House B&B
Hopkins
9.0 out of 10, Wonderful, (20)
"A truly magical place. What an amazing stay. "
United States
Eric F.
Cottage Tree House B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Orangeburg Hotel Reviews

Find out more about Orangeburg

Search for holiday rentals in Orangeburg on Expedia! You can easily find your home rentals, villas, holiday apartments in Orangeburg using one of the methods below:

  • View our selection of featured holiday rentals in Orangeburg
  • Use the map to find apartments and other holiday homes in the Orangeburg neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Orangeburg while they last

Look no further and take a look at our great range of rental properties in Orangeburg!

Frequently asked questions

Can I find a vacation rental in Orangeburg?

Yes, we give you a choice of vacation rentals in Orangeburg close to Edisto Memorial Gardens, or you can choose a secluded option if you want a relaxing stay. Tourists appreciate the top-notch restaurants in Orangeburg. Make sure you have time to check out the gardens and university setting during your trip.

What are some of the best vacation rentals that Orangeburg has to offer?

Nene’s Cozy Corner: This highly rated vacation home rental in Orangeburg has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Another good choice for your trip to Orangeburg is Your 4 bedroom 3 full bathroom Orangeburg Oasis awaits!!!!.

How many vacation rentals will I find in Orangeburg?

With 15 Expedia vacation rentals, you're sure to find just the right place for your Orangeburg stay.

What’s there to see and do in Orangeburg?

Explore the area and family-friendly sights such as I.P. Stanback Museum & Planetarium, or get out into nature at a spot like Edisto Memorial Gardens. South Carolina State College Historic District and Smith-Hammond-Middleton Memorial Center are other places to visit while you're in town.

What’s a vacation rental in Orangeburg like?

Vacation rentals are private properties you can stay in for a couple of days or more in Orangeburg. Vacation rentals feature amenities like laundry facilities and kitchens so you'll feel just like you're at home. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for a small group gathering.