Find hotels near Murphy Island, Palmyra from ￥10,280

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Dec 25 - Dec 26
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Dec 26 - Dec 27
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Dec 26 - Dec 28
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Our top choices for Murphy Island hotels

Exterior
Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West

Sleep Inn & Suites Hannibal West
2.5 star property
6.1 km from Murphy Island
9.6 out of 10, Exceptional, (1002)
"Very personable staff, easy check in"
United States
Cherie
The price is ￥15,101
￥17,495 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Sleep Inn & Suites Hannibal West
55-inch TV with cable channels, Netflix, Hulu
Riverside Inn Hannibal

Riverside Inn Hannibal

Riverside Inn Hannibal
2.5 star property
4.9 km from Murphy Island
9.4 out of 10, Exceptional, (165)
"Great place to stay!"
United States
Sandy
The price is ￥23,872
￥32,790 total
includes taxes & fees
Dec 27 - Dec 28
Riverside Inn Hannibal
Deluxe Room | Down comforters, blackout drapes, iron/ironing board, free WiFi
Lighthouse Inn & Suites

Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
4.3 km from Murphy Island
8.8 out of 10, Excellent, (24)
"Very nice room, close enough to walk to riverfront attractions. "
United States
Robert
The price is ￥26,331
￥30,242 total
includes taxes & fees
Dec 27 - Dec 28
Lighthouse Inn & Suites
Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers
Best Western On The River

Best Western On The River

Best Western On The River
2.5 star property
4.7 km from Murphy Island
8.6 out of 10, Excellent, (1001)
"Great stay! Clean and cozy!!"
United States
Courtney
The price is ￥15,748
￥18,087 total
includes taxes & fees
Dec 28 - Dec 29
Best Western On The River
Front of property
Garden House Bed and Breakfast

Garden House Bed and Breakfast

Garden House Bed and Breakfast
2.0 star property
4.9 km from Murphy Island
8.6 out of 10, Excellent, (38)
"Overall stay was great and the host chris is great aswell nothing bad to say about any aspect of our stay!"
United States
Josh
The price is ￥16,701
￥19,181 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Garden House Bed and Breakfast
Lobby
Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West
2.5 star property
6 km from Murphy Island
8.0 out of 10, Very Good, (1006)
"Very friendly staff. "
United States
Lawrence
The price is ￥10,933
￥12,665 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Inn & Suites Hannibal West
Indoor pool, sun loungers
Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
2.5 star property
7.3 km from Murphy Island
7.6 out of 10, Good, (661)
"Below average facility. Needs some upgrades and could use a good cleaning. Staff was helpful."
United States
JACQUI
The price is ￥11,851
￥14,080 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Comfort Inn & Suites - Hannibal
Lobby sitting area
Motel 6 Hannibal, MO

Motel 6 Hannibal, MO

Motel 6 Hannibal, MO
2.0 star property
5.7 km from Murphy Island
7.4 out of 10, Good, (1001)
"Very clean rooms and staff is very friendly "
United States
Sherrie
The price is ￥9,043
￥10,386 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Motel 6 Hannibal, MO
Exterior
Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal

Super 8 by Wyndham Hannibal
2.0 star property
5.6 km from Murphy Island
7.2 out of 10, Good, (1000)
"My stay was excellent staff very friendly and breakfast was always great "
United States
Sherrie
The price is ￥9,122
￥10,477 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Super 8 by Wyndham Hannibal
Room, 2 Queen Beds, Non Smoking | Desk, laptop workspace, free WiFi, bed sheets
Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal

Days Inn by Wyndham Hannibal
2.0 star property
7.4 km from Murphy Island
7.4 out of 10, Good, (217)
"Left before breakfast great cup of coffee"
United States
David
The price is ￥10,604
￥12,178 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Days Inn by Wyndham Hannibal
Lobby sitting area
Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal

Howard Johnson BY Wyndham Hannibal
2.0 star property
7.5 km from Murphy Island
7.2 out of 10, Good, (153)
"The gentleman at the front desk was extremely nice and did everything to make my stay wonderful. The breakfast was awesome. The pool was sooo nice. The exercise room was great. I cannot say anything bad about this hotel. This was the first time I stayed here and I will be coming back every three months.!"
United States
Shawn
The price is ￥8,889
￥10,280 total
includes taxes & fees
Dec 28 - Dec 29
Howard Johnson BY Wyndham Hannibal
Desk, laptop workspace, iron/ironing board, free WiFi
Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal

Baymont by Wyndham Hannibal
2.5 star property
7.4 km from Murphy Island
6.4 out of 10, (737)
" There actually was a pool & there actually was a hot breakfast. It didn't just say there was & not have what was listed. One of the best we've been to as of late. Would stay again if in the area. "
United States
Thomas
The price is ￥9,122
￥10,547 total
includes taxes & fees
Dec 28 - Dec 29
Baymont by Wyndham Hannibal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Murphy Island Hotel Reviews

Quality Inn & Suites Hannibal West

Quality Inn & Suites Hannibal West

10/10 Excellent
"Comfortable bed, nice room, excellent breakfast. A++ and will stay again. Reasonable price and excellent bar and grill across parking lot."
Mildred 1-night trip
Posted 2 days ago
Quality Inn & Suites Hannibal West

Hotels near other Murphy Island attractions

Mark Twain Memorial Lighthouse

4.3/5 (93 reviews)
You can find out about the history of Hannibal with a stop at Mark Twain Memorial Lighthouse. While in this walkable area, you can savor the top-notch restaurants.
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Riverview Park

You can find out about the history of Hannibal with a visit to Riverview Park. While in this family-friendly area, you can savor the top-notch restaurants.
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Frequently asked questions

What's the area like around Murphy Island?
Murphy Island is located in Palmyra. You'll find 52 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to Murphy Island?
Quality Inn & Suites Hannibal West is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 3.7 mi (6 km) from Murphy Island. Other good options within a few miles include Sleep Inn & Suites Hannibal West and Lighthouse Inn & Suites.
How many hotels will I be able to find near Murphy Island?
Expedia has 52 hotels and other accommodations a few miles from Murphy Island.
If I need to cancel the hotel reservation for my stay near Murphy Island, will I receive a refund?
Yes, you'll find most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals available near Murphy Island.
Where can I learn more about changing or cancelling my trip in the area near Murphy Island?
For more information about rescheduling or cancelling your stay near Murphy Island, click here.
What can I see and do near Murphy Island?
Molly Brown Museum and Home, Mark Twain Boyhood Home and Museum, and Jim's Journey: The Huck Finn Freedom Center feature captivating exhibits. Mark Twain Memorial Lighthouse, Rockcliffe Mansion, and Planters Barn Theater are landmarks that you won't want to miss. You might spend a leisurely day outdoors at Sawyer's Creek Fun Park and Sodalis Nature Preserve.