The Best Hotels Closest to Murphy Island in Palmyra for 2026

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Our top choices for Murphy Island hotels

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

1. Sleep Inn & Suites Hannibal West

6.1 km from Murphy Island

Patricia

￥18,260

￥21,246 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

2. Best Western On The River

4.7 km from Murphy Island

Raymond

￥17,299

￥19,954 total

includes taxes & fees

Sep 28 - Sep 29

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A historic building with a stone facade and multiple windows, featuring a sign about Tom Sawyer's fence.

A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

A wooden table with a bottle of champagne, two glasses, and scattered rose petals.

3. Riverside Inn Hannibal

4.9 km from Murphy Island

Jack

￥23,852

￥32,956 total

includes taxes & fees

Sep 28 - Sep 29

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

4. Quality Inn & Suites Hannibal West

6 km from Murphy Island

Kenneth

￥12,527

￥14,576 total

includes taxes & fees

Oct 11 - Oct 12

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A dining area with a table set for four, surrounded by wooden chairs. A chandelier hangs above the table, and a lamp provides additional lighting.

A fireplace with decorative elements, framed pictures, and a vase of red flowers.

A cozy living room with a fireplace, a red armchair, a globe, and various framed pictures on the mantel.

5. Garden House Bed and Breakfast

4.9 km from Murphy Island

Edward

￥12,678

￥14,624 total

includes taxes & fees

Sep 30 - Oct 1

A hotel room with a bed, a sofa, a desk, and a lamp.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

6. Comfort Inn & Suites - Hannibal

7.3 km from Murphy Island

Charles

￥11,533

￥13,776 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A swimming pool with lounge chairs and a covered seating area.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

7. Lighthouse Inn & Suites

4.3 km from Murphy Island

Kari

￥26,558

￥30,633 total

includes taxes & fees

Sep 28 - Sep 29

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A coffee station with a coffee machine, cups, and a sign that says "RISE & SHINE."

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

A building with a covered entrance and a sign indicating a clearance height of 13 feet.

8. Motel 6 Hannibal, MO

5.7 km from Murphy Island

Donna B

￥9,119

￥10,519 total

includes taxes & fees

Sep 29 - Sep 30

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A patio with red Adirondack chairs and a table, surrounded by a pebble border.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

A long hallway with a patterned carpet, wooden paneling on the walls, and a ceiling light.

9. Super 8 by Wyndham Hannibal

5.6 km from Murphy Island

Betty

￥9,712

￥11,203 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with two beds, a wooden headboard, a nightstand with a phone and lamp, and a large sunset painting above the beds.

A kitchenette with a bread display, a microwave, a toaster, and a coffee maker on a small table.

A laundry room with a washing machine, dryer, and a shelf with detergent bottles.

A reception area with a marble counter, a 'Days Inn' sign, and a welcome mat.

10. Days Inn by Wyndham Hannibal

7.4 km from Murphy Island

Oressa

￥8,825

￥10,180 total

includes taxes & fees

Oct 4 - Oct 5

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A kitchen with wooden cabinets, a granite countertop, and various food items and kitchen appliances.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

A hotel room with two beds, a desk, a chair, and a telephone.

11. Howard Johnson BY Wyndham Hannibal

7.5 km from Murphy Island

Debbie

￥10,011

￥11,625 total

includes taxes & fees

Oct 4 - Oct 5

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A hotel room with a bed, a desk with a chair, a television, and a desk lamp.

A gym with cardio equipment, mirrored walls, and a view of a Pepsi store outside.

12. Baymont by Wyndham Hannibal

7.4 km from Murphy Island

brian

￥8,690

￥10,091 total

includes taxes & fees

Sep 29 - Sep 30

A rooftop terrace with a brick wall, a metal railing, and a table with chairs.

A storefront with a red and gray facade, large windows, and various beer advertisements.

A rustic living room with exposed brick walls, wooden beams, and a cozy fireplace. There are two leather sofas with throw pillows and a fluffy rug.

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a trash bin.

13. Deck + River View: Loft in Downtown Hannibal

4.9 km from Murphy Island

￥21,705

￥41,683 total

includes taxes & fees

Sep 29 - Sep 30

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Compare popular hotels close to Murphy Island

Property	Star rating	Guest rating
Sleep Inn & Suites Hannibal West	9.6 Exceptional 1,000 reviews	View
Best Western On The River	8.6 Excellent 1,007 reviews	View
Riverside Inn Hannibal	9.6 Exceptional 199 reviews	View
Quality Inn & Suites Hannibal West	8.0 Very good 1,011 reviews	View
Garden House Bed and Breakfast	8.4 Very good 53 reviews	View

Top Murphy Island Hotel Reviews

Quality Inn & Suites Hannibal West

8/10 Good

"Our go to hotel for years when we visit Hannibal."

Riverside Inn Hannibal

10/10 Excellent

"Great place to stay!!"

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

10/10 Excellent

"Loved this house perfect for what we needed."

Garden House Bed and Breakfast....Cozy 1895 Queen Anne Victorian,

8/10 Good

"We really enjoyed our stay and especially loved the cat hostess. We are both cat lovers and are without cats at the moment so that was just sweet. We were disappointed to find that breakfast wasn’t served at the bed-and-breakfast and which was advertised on the in the listing, but our host said that it was a separate add-on, Chris, our host was very helpful when we accidentally left a bag behind and we had to drive over and pick it up from him. He was very gracious to meet us."

Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown

8/10 Good

"This house is very old and interesting with some interesting history. I love old houses and this place has some unique details. The pool was an added detail that we didn’t use much, but would be fun for families with children. The surrounding back yard was very private and shady. Convenient to downtown and the river."

Vibey home a few blocks from downtown Hannibal

10/10 Excellent

"Clean, comfortable and roomy. Excellent host."

Amazing Hannibal Home - Eitaly’s on Paris

10/10 Excellent

"It is a bargain, and the location to the Mark Twain area is excellent for walking or driving would be a great place to be our Fourth of July celebration and any other time. It’s really set up for a family with adults, older children, and a lot of kids cause they’ve got a lot of sleeping here even though we only use two beds. I would recommend the host as he is pretty communicative and a couple of problems we had or easily solved with that communication. There is a great washer and dryer microwave refrigerator lots of coffee options in a great TV with Option. Enjoy your stay it’s reasonable. It’s not priced real high and for the value that we put into it. It was exactly what we expected and glad we went. probably go again when we go back to Hannibal I am a native Hannibal so I’m speaking from that perspective. Make sure you do the steps to the lighthouse and remember that the guy that you stayed in his house, actually lived in that little tiny house right next to the blanket."

Experience Hannibal, MO from this historic home built in 1844

10/10 Excellent

"An amazing historic home. We basically parked the car for two days after visiting the cave. Loved getting to walk to everything. The home was lovely. I had my 9 and 5yo daughters and they loved the porches best of all. The beds were comfortable. Amazing air conditioning. Well stocked kitchen! The neighborhood is undergoing some “reconstruction” but we felt very safe in the neighborhood. Two things to be aware of: the door frames are low. My 6’2 husband discovered that quickly. There is one shower bathroom upstairs and it is “cozy”. If you are a large person you may find it tight, but really it is workable. The shower was fantastic and had great water pressure and hot water. It was a beautiful stay and I’d recommend it. Be sure to visit the Mark Twain cave. It is a maze cave and so fascinating. We ate at the Mark Twain Dinnett ans Java Jive twice because we liked the food so much and it was walkable, but there are other options. The sandwich counter at Clemens looked great be we had already eaten. Have a great trip!"

Modern and comfy home five minutes from downtown

10/10 Excellent

"Perfect location for our quick getaway. Short drive to downtown Hannibal. Comfortable accomodations. Well furnished. Would stay again if visiting Hannibal. "

Other attractions near Murphy Island

Mark Twain Memorial Lighthouse

8.8/10 (143 reviews)

You can find out about the history of Hannibal with a stop at Mark Twain Memorial Lighthouse. While in this family-friendly area, you can savor the top-notch restaurants.

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Riverview Park

You can find out about the history of Hannibal with a visit to Riverview Park. While in this family-friendly area, you can savor the top-notch restaurants.

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Bay Island

Commune with nature and explore the great outdoors at Bay Island during your travels in Palmyra. Take in the museums while you're in the area.

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Indian Mounds Park

After visiting Indian Mounds Park, make a plan to see the other sights and activities in Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.

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Veteran's Sports Park

Veteran's Sports Park is just one of the places to see in Hannibal, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.

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Molly Brown Museum and Home

8.4/10 (64 reviews)

You can browse the exhibits at Molly Brown Museum and Home, a museum with a story of its own, during your travels to Hannibal. While in this walkable area, you can savor the top-notch restaurants.

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Jim's Journey: The Huck Finn Freedom Center

8.4/10 (33 reviews)

You can browse the exhibits at Jim's Journey: The Huck Finn Freedom Center, a museum with a story of its own, during your travels to Hannibal. While in this family-friendly area, you can savor the top-notch restaurants.

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Mark Twain Boyhood Home and Museum

9.0/10 (278 reviews)

Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this family-friendly area, you can savor the top-notch restaurants.

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Frequently asked questions

What's the area like around Murphy Island?

Murphy Island is located in Palmyra. You'll find 54 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay close to Murphy Island?

Quality Inn & Suites Hannibal West is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 3.7 mi (6 km) from Murphy Island. Other good options within a few miles include Best Western On The River and Comfort Inn & Suites - Hannibal.

How many hotels will I be able to find near Murphy Island?

Expedia has 54 hotels and other accommodations a few miles from Murphy Island.

If I need to cancel the hotel reservation for my stay near Murphy Island, will I receive a refund?

Yes, you'll find most hotel reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals available near Murphy Island.

Where can I learn more about changing or cancelling my trip in the area near Murphy Island?

For more information about rescheduling or cancelling your stay near Murphy Island, click here.

What can I see and do near Murphy Island?

Jim's Journey: The Huck Finn Freedom Center, Mark Twain Boyhood Home and Museum, and Molly Brown Museum and Home feature captivating exhibits. Mark Twain Memorial Lighthouse, Rockcliffe Mansion, and Bluff City Theater are landmarks that you won't want to miss. You might spend a leisurely day outdoors at Sodalis Nature Preserve and Sawyer's Creek Fun Park.

Find hotels near Murphy Island, Palmyra from ￥10,091

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Murphy Island hotels

1. Sleep Inn & Suites Hannibal West

2. Best Western On The River

3. Riverside Inn Hannibal

4. Quality Inn & Suites Hannibal West

5. Garden House Bed and Breakfast

6. Comfort Inn & Suites - Hannibal

7. Lighthouse Inn & Suites

8. Motel 6 Hannibal, MO

9. Super 8 by Wyndham Hannibal

10. Days Inn by Wyndham Hannibal

11. Howard Johnson BY Wyndham Hannibal

12. Baymont by Wyndham Hannibal

13. Deck + River View: Loft in Downtown Hannibal

Compare popular hotels close to Murphy Island

Top Murphy Island Hotel Reviews

Quality Inn & Suites Hannibal West

Riverside Inn Hannibal

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Garden House Bed and Breakfast....Cozy 1895 Queen Anne Victorian,

Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown

Vibey home a few blocks from downtown Hannibal

Amazing Hannibal Home - Eitaly’s on Paris

Experience Hannibal, MO from this historic home built in 1844

Modern and comfy home five minutes from downtown

Other attractions near Murphy Island

Mark Twain Memorial Lighthouse

Riverview Park

Bay Island

Indian Mounds Park

Veteran's Sports Park

Molly Brown Museum and Home

Jim's Journey: The Huck Finn Freedom Center

Mark Twain Boyhood Home and Museum

Frequently asked questions