The Best Hotels Closest to Mark Twain Medical Center in San Andreas for 2026

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Our top choices for Mark Twain Medical Center hotels

A large, two-story house with a prominent porch and a well-maintained lawn.

A porch with white chairs and a table, a wooden floor, and a view of trees through a window.

A garden pathway with a wooden fence and steps leading to a building.

A room with a sofa, two side tables, a decorative window with curtains, and a floral arrangement.

1. Robin's Nest Inn

1.6 km from Mark Twain Medical Center

ROBERT

￥22,123

￥24,778 total

includes taxes & fees

Nov 2 - Nov 3

A hotel room with two beds, a desk with a coffee maker, a couch, and artwork on the walls.

A Sierra Inn sign with a 'VACANCY' notice, a stop sign, and a parking lot with cars.

A glass-enclosed shower stall with a white toilet adjacent to it.

A multi-story motel with a flat roof, large windows, and a parking lot.

2. Sierra Inn

1.2 km from Mark Twain Medical Center

Eddie

￥14,035

￥16,958 total

includes taxes & fees

Oct 30 - Oct 31

A spacious living room with a sofa, armchairs, ottomans, a glass coffee table, and a large window with curtains.

A swimming pool with a metal ladder, surrounded by a fence, trees, and a building with a tiled roof.

A hotel with a covered entrance, a sign indicating 'Best Western' and 'Cedar Inn & Suites', and a 'No Vacancy' sign.

A modern dining area with wooden tables and grey upholstered chairs, a kitchen area with a coffee station, and a flat-screen TV mounted on the wall.

3. Best Western Cedar Inn & Suites

16.2 km from Mark Twain Medical Center

Todd

￥17,531

￥19,635 total

includes taxes & fees

Oct 28 - Oct 29

A spacious lobby with a reception desk, wooden paneling, a large mural, and a view through the glass doors.

A staircase with a wooden railing leading to a stone fireplace, a patterned rug, and a mural on the wall.

A parking lot with several classic cars parked in front of a building with a green roof.

A hotel lobby with a patterned carpet, a green sofa, a wooden railing, and a stone wall with a mural.

4. Murphys Suites

19.8 km from Mark Twain Medical Center

Melani

￥16,401

￥18,369 total

includes taxes & fees

Nov 1 - Nov 2

A reception desk with a sign reading "National Hotel NH" and a "Registration" sign.

A covered porch with a white balustrade, wicker furniture, and a view of a red brick building.

A dining table set with wine glasses, a candle, and a vase with a flower.

A grand piano, a staircase, and a wooden cabinet with a framed portrait in a room with patterned wallpaper and a wooden floor.

5. National Hotel Jackson, Tapestry Collection by Hilton

19.7 km from Mark Twain Medical Center

Lindsey

￥17,417

￥19,507 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with two beds, a desk, a chair, and a television.

A hotel room with a flat-screen TV on a black entertainment unit, a desk with a lamp, a small refrigerator, and a microwave.

A building with a balcony, outdoor tables and benches, and large windows.

A swimming pool with a metal ladder, lounge chairs, and an umbrella.

6. Travelodge by Wyndham Angels Camp CA

14.4 km from Mark Twain Medical Center

Andre

￥12,395

￥13,883 total

includes taxes & fees

Oct 26 - Oct 27

A bed with white bedding and pillows against a wooden headboard.

A fitness room with cardio equipment, a mirror, and a phone on a table.

A conference room with a long table, chairs, and a patterned carpet.

An outdoor patio area with tables and chairs, red umbrellas, and a decorative wall.

7. Holiday Inn Express Hotel & Suites Jackson by IHG

18.8 km from Mark Twain Medical Center

Tasjia

￥17,595

￥19,741 total

includes taxes & fees

Nov 19 - Nov 20

A motel with a covered entrance, American flag, and a sign that reads "ACANNY".

A kitchen with wooden cabinets, a ceiling fan, pendant lights, and a counter with various items.

A hotel room with a bed, a floral sofa, a small table, a chair, and a desk with a computer.

A swimming pool with a chair and umbrella, a small fence, and a building in the background.

8. Murphys Inn Motel

19.6 km from Mark Twain Medical Center

Randall

￥16,213

￥18,158 total

includes taxes & fees

Oct 26 - Oct 27

A small outdoor patio with a table and chairs, a bottle of wine, and a glass of wine.

A room with a fireplace, a clawfoot bathtub, and a wooden chair.

A room with a beige armchair, a small table with a plate of cookies and a cup, and a window with a view of buildings outside.

A room with a checkered floor, a desk with a computer, a sofa, a staircase, and a decorative wall panel.

9. The Victoria Inn

19 km from Mark Twain Medical Center

Alex

￥24,394

￥27,809 total

includes taxes & fees

Oct 27 - Oct 28

A backyard with a stone wall, a swimming pool, outdoor seating, and string lights.

A restaurant with multiple tables, chairs, and a ceiling fan.

A bedroom with a wooden headboard, a large bed with white linens, a small bedside table, a patterned rug, and a stone wall.

A two-story building with a balcony and a sign reading "Hotel Leeger."

10. Hotel Leger

12.7 km from Mark Twain Medical Center

Gary

￥32,187

￥36,050 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, bedside tables, a desk, and a mirror.

A sign for Angels Inn with a digital display and a frog mascot.

A sign for Angels Inn with a frog mascot, a modern building with large windows, and a well-maintained lawn.

A building entrance with a handicap parking sign, a mailbox, and a small window.

11. Angels Inn

16.8 km from Mark Twain Medical Center

Martha

￥14,810

￥18,003 total

includes taxes & fees

Oct 22 - Oct 23

A two-story building with a sloped roof, a covered porch, and a parking area with cars.

A room with a ceiling fan, a television mounted on the wall, a fireplace, and a large window with blinds.

A golf course with a flag, trees, and a clear sky.

A covered outdoor seating area with a grill, chairs, and an umbrella.

12. The 10th Green Inn

14.3 km from Mark Twain Medical Center

William

￥18,244

￥20,433 total

includes taxes & fees

Nov 18 - Nov 19

A kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a granite countertop.

A hotel room with two beds, a desk, a window with blinds, and a ceiling light.

A modern living room with a round coffee table, two armchairs, a sofa, a side table with a lamp, and a mirror on the wall.

A row of brick buildings with a parking lot in front.

13. Best Western Amador Inn

19.5 km from Mark Twain Medical Center

Daniel

￥13,313

￥14,911 total

includes taxes & fees

Nov 1 - Nov 2

A green house with a red roof, a white building with an orange awning, and a large tree in the foreground.

A motel with multiple rooms, a parking area, and a grassy lawn.

A garden with deer statues, a tree, and a brick pathway.

A small room with a ceiling light, an air conditioning unit, a power outlet, and a wooden table.

14. Jumping Frog Motel

15.9 km from Mark Twain Medical Center

Michael

￥11,603

￥12,996 total

includes taxes & fees

Oct 22 - Oct 23

A two-story house with a front porch, a brick pathway leading to the entrance, and a well-maintained garden.

A white picket fence, a wooden arbor with climbing plants, and a flag.

A paved pathway leading to a white house with black shutters, flanked by walls with potted plants and decorative urns.

A banquet hall with multiple round tables set for dining, featuring white tablecloths, candles, and floral centerpieces.

15. Dunbar House Inn and Event Property

19.2 km from Mark Twain Medical Center

Samson

￥34,290

￥39,091 total

includes taxes & fees

Oct 22 - Oct 23

View all properties

Compare popular hotels close to Mark Twain Medical Center

Property	Star rating	Guest rating
Robin's Nest Inn	9.6 Exceptional 148 reviews	View
Sierra Inn	7.6 Good 182 reviews	View
Best Western Cedar Inn & Suites	9.0 Wonderful 1,001 reviews	View
Murphys Suites	9.2 Wonderful 1,007 reviews	View
National Hotel Jackson, Tapestry Collection by Hilton	9.4 Exceptional 1,003 reviews	View

Top Mark Twain Medical Center Hotel Reviews

Murphys Inn Motel

10/10 Excellent

"The property was very clean, with good parking, the beds were comfortable, The front desk clerk, Kellie, was very nice and friendly, I would definitely stay there again. Good bargain for the money."

Best Western Amador Inn

10/10 Excellent

"Excellent property! smell so good and clean I very happy to stay in this hotel every single time"

Heritage Inn Yosemite/Sonora

10/10 Excellent

"Great place."

Jumping Frog Motel

10/10 Excellent

"If you want to see a time gone by roadside hotel. This is it. It is not perfect. But if you want perfect. You wouldn't be here. Room for parking and turning around. Next door to a Mexican fast food joint and a Harvey-Davisson fixer upper shop that loved to test their bikes at all hours and watch the oil leak off of them. No BMW bikers here."

WorldMark Angels Camp

10/10 Excellent

"Very nice. 2nd time staying there and I would stay again as it was a good value for amenities they provide."

The Victoria Inn

10/10 Excellent

"I enjoyed staying there! The staff were amazing and the continental breakfast was a delight. Thank you, I will come again!"

Holiday Inn Express Hotel & Suites Jackson by IHG

8/10 Good

"The night staff and the day staff were always friendly, kind, and helpful. The drive from Yosemite was crazy to get to this quiet little town. The breakfast was good and similar to all the other breakfasts we had during our vacation."

Gateway Hotel, Trademark Collection by Wyndham

10/10 Excellent

"Great place to stay and within walking distance to lots of food and shopping options. Highly recommend!"

Robin's Nest Inn

10/10 Excellent

"Everybody was friendly, attentive to our comfort. Highly recommend!"

Frequently asked questions

What's the area like around Mark Twain Medical Center?

Mark Twain Medical Center is located in San Andreas. You'll find 5 hotels and other accommodations within a few miles for a convenient home base.

What's the best place to stay close to Mark Twain Medical Center?

Robin's Nest Inn is one of the top choices for your stay based on our traveler data, and this B&B offers free parking and a hot tub. It's located just a short 1 mi (1.6 km) from Mark Twain Medical Center. Another good choice is Sierra Inn, located just 0.8 mi (1.2 km) away.

How many hotels should I expect to find close to Mark Twain Medical Center?

Expedia has 5 hotels and other accommodations a few miles from Mark Twain Medical Center.

If I need to cancel the hotel reservation for my stay near Mark Twain Medical Center, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best deals available near Mark Twain Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Mark Twain Medical Center?

To access more information about picking new dates or cancelling your stay near Mark Twain Medical Center, head over to our customer service page.

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Mark Twain Medical Center hotels

1. Robin's Nest Inn

2. Sierra Inn

3. Best Western Cedar Inn & Suites

4. Murphys Suites

5. National Hotel Jackson, Tapestry Collection by Hilton

6. Travelodge by Wyndham Angels Camp CA

7. Holiday Inn Express Hotel & Suites Jackson by IHG

8. Murphys Inn Motel

9. The Victoria Inn

10. Hotel Leger

11. Angels Inn

12. The 10th Green Inn

13. Best Western Amador Inn

14. Jumping Frog Motel

15. Dunbar House Inn and Event Property

Compare popular hotels close to Mark Twain Medical Center

Top Mark Twain Medical Center Hotel Reviews

Murphys Inn Motel

Best Western Amador Inn

Heritage Inn Yosemite/Sonora

Jumping Frog Motel

WorldMark Angels Camp

The Victoria Inn

Holiday Inn Express Hotel & Suites Jackson by IHG

Gateway Hotel, Trademark Collection by Wyndham

Robin's Nest Inn

Frequently asked questions

Find hotels near Mark Twain Medical Center, San Andreas from ￥12,996

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Mark Twain Medical Center hotels

1. Robin's Nest Inn

2. Sierra Inn

3. Best Western Cedar Inn & Suites

4. Murphys Suites

5. National Hotel Jackson, Tapestry Collection by Hilton

6. Travelodge by Wyndham Angels Camp CA

7. Holiday Inn Express Hotel & Suites Jackson by IHG

8. Murphys Inn Motel

9. The Victoria Inn

10. Hotel Leger

11. Angels Inn

12. The 10th Green Inn

13. Best Western Amador Inn

14. Jumping Frog Motel

15. Dunbar House Inn and Event Property

Compare popular hotels close to Mark Twain Medical Center

Top Mark Twain Medical Center Hotel Reviews

Murphys Inn Motel

Best Western Amador Inn

Heritage Inn Yosemite/Sonora

Jumping Frog Motel

WorldMark Angels Camp

The Victoria Inn

Holiday Inn Express Hotel & Suites Jackson by IHG

Gateway Hotel, Trademark Collection by Wyndham

Robin's Nest Inn

Frequently asked questions