Madre de Dios Region Vacations & Trips

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Top destinations in Madre de Dios Region

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Madre de Dios Region Hotel Deals

Libelula Hotel

Libelula Hotel

2 out of 5
Jr Puno No. 429, Tambopata, Madre de Dios
8.8/10 Excellent! (19 reviews)
Great stay, friendly owners and staff.

Reviewed on Jun 22, 2025

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Libelula Hotel
IKAM Riverview Amazon Lodge - Asociado Casa Andina

IKAM Riverview Amazon Lodge - Asociado Casa Andina

3 out of 5
Tambopata KM. 7 Otr. Carretera Bajo, Tambopata, Madre de Dios
The price is ￥32,426 per night from Nov 20 to Nov 21
￥32,426
￥34,047 total
Nov 20 - Nov 21
9/10 Wonderful! (6 reviews)
Half an hour a at from Puerto Maldonado by boat , the place is lovely, with river view and a feel of the jungle without venturing too far. We felt like we got a good insight into the area, with included excursions on the river and into the jungle. Our guide Yuri, who was with us throughout, was very ...

Reviewed on Sep 23, 2025

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Inkaterra Reserva Amazonica

Inkaterra Reserva Amazonica

4 out of 5
Madre De Dios River Km. 15, Las Piedras, Madre de Dios
9.2/10 Wonderful! (43 reviews)
World class!

Reviewed on Oct 19, 2025

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Inkaterra Reserva Amazonica
See all 55 properties in Madre de Dios Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Madre de Dios Region vacation package cost?
Choose from any combination of hotels, flights and car rentals, and you can be vacationing in Madre de Dios Region from just . And the more you bundle, the more money you save. The getaway of your dreams has never been more affordable.
How do I get a cheap travel package to Madre de Dios Region?
Browse and book everything all in one place with our Madre de Dios Region vacation packages. We have incredible bargains on hotels, flights and more that'll keep your pocket happy and your sense of adventure alive. And, with more than 550 airlines and 1,000,000 properties throughout the world to pick from, you'll have endless opportunities to mix and match as you please.
What are the top hotels in Madre de Dios Region?
For properties in Tambopata with friendly service and cozy beds, you can't beat Kapievi Ecovillage and Inkaterra Reserva Amazonica. If you plan to explore Las Piedras as well, you'll get a solid night's sleep at Copasu Hotel or Tarantula Hostel.
How far in advance should I book my Madre de Dios Region vacation?
Reward yourself with the biggest variety and the lowest prices by booking your vacation to Madre de Dios Region nice and early. Airlines generally advertise flight tickets around 12 months prior to departure, so reserve your spot ASAP. Having said that, Expedia is constantly working to give you the best deals around, so it's never a bad time to book your dream vacation!
What does an Expedia Madre de Dios Region travel package include?
Hotels, flights and car rentals — we connect you to the very best bargains. All you have to do is decide on your favorite combination. After you've made your booking, you can add on the fun stuff like sightseeing activities. Our travel packages make it easy to create an awesome Madre de Dios Region getaway.
What should I know before booking a Madre de Dios Region travel package?
When you book your flights, hotels and car rentals together, you'll enjoy amazing discounts. Whether you're planning a mountain getaway in a cabin or want to stay in a cozy apartment in the city, Expedia will help make it happen.
Can I choose my airline with a Madre de Dios Region Expedia vacation package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Madre de Dios Region vacation package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can cancel or change your Madre de Dios Region vacation package. If you booked in the last 24 hours, you may be entitled to a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to find out more.

What to do in Madre de Dios Region

Puerto Maldonado: Kayak and Zip Line Adventure + Monkey Isla

Puerto Maldonado: Kayak and Zip Line Adventure + Monkey Isla

￥9,923
per adult
Puerto Maldonado: Kayak and Zip Line Adventure + Monkey Isla
Puerto Maldonado: 4-Day Tambopata Rainforest Tour

Puerto Maldonado: 4-Day Tambopata Rainforest Tour

￥67,781
per adult
Puerto Maldonado: 4-Day Tambopata Rainforest Tour
Puerto Maldonado: Sandoval Lake Full-Day Trip with Canoeing

Puerto Maldonado: Sandoval Lake Full-Day Trip with Canoeing

￥12,976
per adult
Puerto Maldonado: Sandoval Lake Full-Day Trip with Canoeing
See all activities in Madre de Dios Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.