Find hotels near Louisville Science Center, Louisville from ￥16,324

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Feb 28 - Mar 1
Tomorrow
Mar 1 - Mar 2
Next weekend
Mar 6 - Mar 8
In two weeks
Mar 13 - Mar 15

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Louisville Science Center hotels

Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (450 reviews)
"Great hotel & location"
United States
Ana
The price is ￥28,701
￥33,770 total
includes taxes & fees
Mar 22 - Mar 23
Hotel Distil, Autograph Collection
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Great room, super kind staff"
United States
Rachel
The price is ￥27,901
￥33,609 total
includes taxes & fees
Mar 15 - Mar 16
21c Museum Hotel Louisville
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,000 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is ￥46,191
￥54,349 total
includes taxes & fees
Mar 6 - Mar 7
The Grady
Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,000 reviews)
"Excellent Hotel"
United States
Nairobi
The price is ￥17,156
￥20,187 total
includes taxes & fees
Mar 22 - Mar 23
Homewood Suites by Hilton Louisville Downtown, KY
Interior entrance

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (120 reviews)
"Warm greeting by Carol who shared all the information and details about the property. SUPER charming and convenient location. Highly recommend."
United States
Kelly
The price is ￥28,910
￥32,669 total
includes taxes & fees
Mar 1 - Mar 2
Market Street Inn
Interior

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,183 reviews)
"Beautiful old hotel with a fantastic bar in the lobby"
United States
Karen
The Brown Hotel
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,000 reviews)
"Great stay "
United States
Sarah
The price is ￥16,741
￥19,697 total
includes taxes & fees
Mar 22 - Mar 23
Cambria Hotel Louisville Downtown-Whiskey Row
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (123 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is ￥17,105
￥27,995 total
includes taxes & fees
Mar 31 - Apr 1
Stellar Suites
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (551 reviews)
"The hotel is so clean and easy access to everything downtown."
United States
Erin
The price is ￥17,166
￥20,198 total
includes taxes & fees
Mar 15 - Mar 16
Towneplace Suites By Marriott Louisville Downtown
2 restaurants, breakfast served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (931 reviews)
"Always a great place to stay."
United States
Christopher
The price is ￥15,101
￥17,769 total
includes taxes & fees
Mar 29 - Mar 30
Tempo By Hilton Louisville Downtown Nulu
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (721 reviews)
"Awesome location and the staff was super friendly"
United States
Kelly
The price is ￥15,137
￥17,811 total
includes taxes & fees
Mar 22 - Mar 23
Moxy Louisville Downtown
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,777 reviews)
"Amazing stay! "
United States
Erin
The price is ￥28,557
￥33,601 total
includes taxes & fees
Mar 29 - Mar 30
Omni Louisville Hotel
4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (4,074 reviews)
"Rooms were clean and staff were friendly! "
United States
Amy
The price is ￥19,684
￥23,161 total
includes taxes & fees
Mar 30 - Mar 31
Galt House Hotel Trademark Collection by Wyndham
Lobby lounge

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (626 reviews)
"Nice hotel, super overpriced"
United States
Kevin
The price is ￥17,787
￥20,928 total
includes taxes & fees
Mar 22 - Mar 23
AC Hotel Louisville Downtown
Restaurant

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,000 reviews)
"Great staff, good bar. "
United States
Edward
The price is ￥15,683
￥18,453 total
includes taxes & fees
Mar 22 - Mar 23
Aloft Louisville Downtown
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,158 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is ￥17,883
￥21,041 total
includes taxes & fees
Mar 15 - Mar 16
Embassy Suites Louisville Downtown
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,000 reviews)
"Very nice hotel. Great stay!"
United States
Brad
The price is ￥28,048
￥33,001 total
includes taxes & fees
Mar 21 - Mar 22
Louisville Marriott Downtown
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,044 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is ￥20,926
￥24,622 total
includes taxes & fees
Mar 1 - Mar 2
Hotel Genevieve part of JdV by Hyatt
Lobby sitting area

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.2 km from Louisville Science Center
8.8 out of 10, Excellent, (1,709 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is ￥13,872
￥16,324 total
includes taxes & fees
Mar 15 - Mar 16
Holiday Inn Express & Suites Louisville Downtown by IHG
View from property

TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North
3.0 star property
2.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (660 reviews)
"Best hotel and staff ever "
United States
Cheryl
The price is ￥17,478
￥19,750 total
includes taxes & fees
Mar 16 - Mar 17
TownePlace Suites by Marriott Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Louisville Science Center

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Terrace/patio
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
450 reviews
View
Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe
21c Museum Hotel Louisville
4.5 star property
9.4
Exceptional
1,003 reviews
View
Lobby
The Grady
4.0 star property
9.4
Exceptional
1,000 reviews
View
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
9.4
Exceptional
1,000 reviews
View
Interior entrance
Market Street Inn
3.5 star property
9.8
Exceptional
120 reviews
View

Top Louisville Science Center Hotel Reviews

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent
"The room was great the staff were very friendly and welcoming. Breakfast was great plenty of choices to choose from. "
DeLacia 1-night trip
Posted 2 days ago
Holiday Inn Express & Suites Louisville Downtown by IHG

Hotels near other Louisville Science Center attractions

Exploration of Louisville Slugger Museum in Downtown Louisville, Kentucky on a Sunny Day

Louisville Slugger Museum

4.5/5 (1,200 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
See properties
A great stop! This has to be one of the best museums I’ve been about somebody! Great stop and a fantastic life!
Photo by Corey Dargan
Open Photo by Corey Dargan

Muhammad Ali Center

4.3/5 (298 reviews)
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
See properties

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 308 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, 21c Museum Hotel Louisville is one of the top choices for your stay based on our traveler data, and this hotel offers a full-service spa and a restaurant. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 308 hotels and other accommodations within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.
Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?
For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Thomas Edison House. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace, and Derby Dinner Playhouse.