Find hotels near Louisville Science Center, Louisville from ￥15,233

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jan 12 - Jan 13
Tomorrow
Jan 13 - Jan 14
This weekend
Jan 16 - Jan 18
Next weekend
Jan 23 - Jan 25

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Louisville Science Center hotels

Lobby
The Grady

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,001 reviews)
"Such an amazing hotel...restaurant is delicious! "
United States
Craig
The price is ￥22,878
￥26,918 total
includes taxes & fees
Jan 31 - Feb 1
The Grady
Terrace/patio
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (432 reviews)
"Clean, well appointed, convenient to restaurants and downtown Louisville."
United States
Chris
The price is ￥29,039
￥34,167 total
includes taxes & fees
Feb 1 - Feb 2
Hotel Distil, Autograph Collection
Interior entrance
Louisville Bourbon Inn

Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.9 km from Louisville Science Center
10.0 out of 10, Exceptional, (20 reviews)
"Great breakfast. Frittata, French toast, eggs, bacon, sausage, grapes, toast, biscuits and gravy - all were excellent. "
United States
Gaven
The price is ￥38,913
￥45,165 total
includes taxes & fees
Jan 29 - Jan 30
Louisville Bourbon Inn
Interior entrance
Market Street Inn

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (120 reviews)
"The owner, Carol, and her husband have done an amazing job restoring the building. The woodwork alone is art! Breakfast offered lots of options, was prepared to order, and was the best scrambled eggs I’ve ever had. Our server, Lisa, was friendly, personable, and efficient. "
United States
Marcia
The price is ￥29,251
￥33,055 total
includes taxes & fees
Jan 13 - Jan 14
Market Street Inn
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,007 reviews)
"Excellent place. "
United States
Anatole
The price is ￥20,900
￥25,380 total
includes taxes & fees
Feb 2 - Feb 3
21c Museum Hotel Louisville
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,004 reviews)
"Very friendly and clean! Great stay! "
United States
Jackie
The price is ￥16,702
￥19,651 total
includes taxes & fees
Feb 1 - Feb 2
Homewood Suites by Hilton Louisville Downtown, KY
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,173 reviews)
"Fantastic place to stay in Louisville."
United States
Nathaniel
The price is ￥24,015
￥28,256 total
includes taxes & fees
Jan 18 - Jan 19
The Brown Hotel
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Enjoyed our stay."
United States
Christian
The price is ￥15,489
￥18,223 total
includes taxes & fees
Jan 14 - Jan 15
Cambria Hotel Louisville Downtown-Whiskey Row
Property amenity
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (522 reviews)
"Clean, great staff, great breakfast ! "
United States
Sondra
The price is ￥15,315
￥18,019 total
includes taxes & fees
Feb 1 - Feb 2
Towneplace Suites By Marriott Louisville Downtown
Front of property
DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.8 out of 10, Exceptional, (99 reviews)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is ￥20,521
￥23,819 total
includes taxes & fees
Jan 15 - Jan 16
DuPont Mansion Bed & Breakfast
Lounge
Stellar Suites

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (119 reviews)
"The check-in process was simple and easy, the room was spotless and had so many amenities. "
United States
Grace
The price is ￥16,766
￥27,708 total
includes taxes & fees
Feb 2 - Feb 3
Stellar Suites
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,765 reviews)
"Beautiful, spacious hotel. Spotless room, kind and helpful staff."
United States
Gizella
The price is ￥26,399
￥31,061 total
includes taxes & fees
Jan 24 - Jan 25
Omni Louisville Hotel
Interior entrance
Moxy Louisville Downtown

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (707 reviews)
"Awesome location and the staff was super friendly"
United States
Kelly
The price is ￥14,052
￥16,534 total
includes taxes & fees
Feb 1 - Feb 2
Moxy Louisville Downtown
2 restaurants, breakfast served
Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (868 reviews)
"Great location, nice staff, good food. "
United States
Zhang
The price is ￥16,196
￥19,057 total
includes taxes & fees
Jan 27 - Jan 28
Tempo By Hilton Louisville Downtown Nulu
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (3,980 reviews)
"Great stay"
United States
Carlos
The price is ￥21,047
￥24,764 total
includes taxes & fees
Jan 28 - Jan 29
Galt House Hotel Trademark Collection by Wyndham
Reception
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,150 reviews)
"Great room and breakfast. Close to several nice restaurants."
United States
Crystal
The price is ￥19,162
￥22,547 total
includes taxes & fees
Jan 26 - Jan 27
Embassy Suites Louisville Downtown
Exterior
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.2 km from Louisville Science Center
8.8 out of 10, Excellent, (1,676 reviews)
"Room was clean and the beds were very comfortable. Would definitely stay here again."
United States
Talva
The price is ￥12,947
￥15,233 total
includes taxes & fees
Jan 18 - Jan 19
Holiday Inn Express & Suites Louisville Downtown by IHG
Restaurant
Aloft Louisville Downtown

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,002 reviews)
"Great room and location and always a plus when pets can stay for free!"
United States
Elizabeth
The price is ￥15,868
￥18,671 total
includes taxes & fees
Feb 1 - Feb 2
Aloft Louisville Downtown
Exterior
Louisville Marriott Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1,002 reviews)
"Very nice hotel. Great stay!"
United States
Brad
The price is ￥28,379
￥33,391 total
includes taxes & fees
Feb 1 - Feb 2
Louisville Marriott Downtown
Terrace/patio
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,029 reviews)
"Spotless room and courteous staff "
United States
Mary
The price is ￥18,331
￥21,569 total
includes taxes & fees
Jan 14 - Jan 15
Hotel Genevieve part of JdV by Hyatt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Louisville Science Center Hotel Reviews

Omni Louisville Hotel

Omni Louisville Hotel

10/10 Excellent
"Everything was perfect. The ONLY one downside was that I asked for a late check out and on the website it was posted one amount, but the attendant told me something different. It still worked out, BUT THE HOTEL WAS AMAZING. Definitely will return"
Chanda 2-night trip
Posted 22 hours ago
Omni Louisville Hotel

Hotels near other Louisville Science Center attractions

Exploration of Louisville Slugger Museum in Downtown Louisville, Kentucky on a Sunny Day

Louisville Slugger Museum

4.5/5 (1,200 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
See properties
A great stop! This has to be one of the best museums I’ve been about somebody! Great stop and a fantastic life!
Photo by Corey Dargan
Open Photo by Corey Dargan

Muhammad Ali Center

4.3/5 (298 reviews)
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
See properties

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 307 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 307 hotels and other accommodations within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.
Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?
For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Thomas Edison House. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace, and Derby Dinner Playhouse.