La Serena Vacation Rentals

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Check prices for these dates

Tonight
Dec 24 - Dec 25
Tomorrow
Dec 25 - Dec 26
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for La Serena vacation rentals

Front of property
Apart Hotel y Cabañas Vegasur

Apart Hotel y Cabañas Vegasur

Apart Hotel y Cabañas Vegasur
3.0 star property
La Serena
8.6 out of 10, Excellent, (93)
"LIMPIEZA BUENA, NO TENGO REPAROS AL RESPECTO."
Chile
Martin
Apart Hotel y Cabañas Vegasur
32-inch flat-screen TV with cable channels, first-run movies
Domos Dream hotel cabañas

Domos Dream hotel cabañas

Domos Dream hotel cabañas
2.0 star property
La Serena
8.6 out of 10, Excellent, (4)
"It was far away."
Mexico
Sergio
The price is ￥12,365
￥12,365 total
Dec 25 - Dec 26
Domos Dream hotel cabañas
3 outdoor pools, open 11:00 AM to 8:00 PM, pool umbrellas
Cabaña Villa Los Plátanos

Cabaña Villa Los Plátanos

Cabaña Villa Los Plátanos
3.0 star property
La Serena
10.0 out of 10, Exceptional, (2)
The price is ￥12,894
￥12,894 total
Dec 26 - Dec 27
Cabaña Villa Los Plátanos
Front of property
IndomitoElqui

IndomitoElqui

IndomitoElqui
2.0 star property
Paiguano
10.0 out of 10, Exceptional, (1)
The price is ￥11,145
￥16,305 total
Dec 25 - Dec 26
IndomitoElqui
Private kitchen
Oceana Suites - Laguna Aculeo

Oceana Suites - Laguna Aculeo

Oceana Suites - Laguna Aculeo
2.0 star property
Coquimbo
The price is ￥23,418
￥46,836 total
Dec 28 - Dec 29
Oceana Suites - Laguna Aculeo
Family Cabin, 2 Bedrooms | Private kitchen | Full-size fridge, microwave, oven, electric kettle
Cabañas de la Costa

Cabañas de la Costa

Cabañas de la Costa
3.0 star property
La Serena
10.0 out of 10, Exceptional, (1)
"They were very hospitable. And I would recommend it to anybody that comes to coquimbo."
United States
Erwin
The price is ￥20,795
￥20,795 total
Jan 1 - Jan 2, 2026
Cabañas de la Costa
Exterior
Cabañas Yunkai

Cabañas Yunkai

Cabañas Yunkai
3.0 star property
Vicuña
The price is ￥13,157
￥13,157 total
Dec 25 - Dec 26
Cabañas Yunkai
Exterior
Parcela Los Nonos

Parcela Los Nonos

Parcela Los Nonos
3.0 star property
Vicuña
Parcela Los Nonos
Exterior
Yunkai Home

Yunkai Home

Yunkai Home
2.0 star property
Vicuña
The price is ￥15,308
￥15,308 total
Dec 27 - Dec 28
Yunkai Home
In-room safe, free WiFi, bed sheets
ELDEPTO LA SERENA

ELDEPTO LA SERENA

ELDEPTO LA SERENA
3.0 star property
Coquimbo
6.0 out of 10, (1)
ELDEPTO LA SERENA
Classic Apartment, Ocean View | Private kitchen
Depto Serena Golf

Depto Serena Golf

Depto Serena Golf
2.0 star property
La Serena
The price is ￥36,118
￥46,437 total
Jan 1 - Jan 2, 2026
Depto Serena Golf
Front of property
Club Playa Blanca

Club Playa Blanca

Club Playa Blanca
2.5 star property
Coquimbo
6.0 out of 10, (2)
"The view was amazing. Property was well kept."
United States
claudia
Club Playa Blanca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Serena Hotel Reviews

Hotel Canto del Mar

Hotel Canto del Mar

4/10 Poor
"Staff was good but we encountered major issues having no water for showers and or bathroom after returning from a desert trips, no prior notice not once but two days in a row . Room facing the beach very very noice at night time with traffic and teen kids skating and bikes until well past midnight. "
Daniel F 4-night trip
Posted 5 days ago
Hotel Canto del Mar

Find out more about La Serena

Search for holiday rentals in La Serena on Expedia! You can easily find your home rentals, villas, holiday apartments in La Serena using one of the methods below:

  • View our selection of featured holiday rentals in La Serena
  • Use the map to find apartments and other holiday homes in the La Serena neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in La Serena while they last

Look no further and take a look at our great range of rental properties in La Serena!

Frequently asked questions

Can I find a vacation rental in La Serena?

Yes, we give you a choice of vacation rentals in La Serena near Jardin del Corazon, or you can go with a more remote option if you're looking for a relaxing stay. La Serena is known for its sightseeing tours and spas. Make sure you have time to check out the casinos while you're in the area.

What are some of the best vacation rentals in La Serena?

Lagoon beach coloso 104: Visitors like this La Serena vacation home rental. It comes with laundry facilities so you can feel at home during your trip. Kitchen amenities include a fridge, an oven, and a microwave. Some other homes for rent in La Serena include lagoon beach white 803 and Family House near the Lighthouse.

How many vacation rentals will I find in La Serena?

With 17 Expedia vacation rentals, you're sure to find just the right place for your La Serena stay.

What can I see and do in La Serena?

Cultural attractions include President Gabriel González Videla Regional History Museum and Casa Gabriel Gonzalez Videla Historical Museum, whereas Kokoro No Niwa Japanese Garden and La Serena Beach are a couple of picturesque spots to enjoy the outdoors. While here, Mall Plaza La Serena and La Serena Lighthouse are other places worth a visit.

What are vacation rentals like in La Serena?

Vacation rentals are private accommodations you can reserve for a short or long stay in La Serena. Vacation rentals provide amenities like kitchens and laundry facilities so you'll be comfy for your stay. If you're concerned about a sanitized environment, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great option for a family trip.