Irene Vacation Rentals

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Check prices for these dates

Tonight
Dec 22 - Dec 23
Tomorrow
Dec 23 - Dec 24
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Irene vacation rentals

Interior
Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!

Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!

Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
Yankton
10.0 out of 10, Exceptional, (22)
"Clean, cute, well-appointed. Great for a girls trip. Close to public beach."
United States
Mandi B.
The price is ￥99,241
￥137,978 total
includes taxes & fees
Dec 23 - Dec 24
Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
Interior
ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18

ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18

ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18
Yankton
9.8 out of 10, Exceptional, (62)
"Communication was excellent with the owner. It has a beautiful view of the lake. The place was very clean, and we had so much fun! Located close to the marina, so getting the boat in was very convenient. Excellent for large groups/families."
United States
Cassidy C.
The price is ￥99,241
￥137,978 total
includes taxes & fees
Dec 29 - Dec 30
ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18
Exterior
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
2.0 star property
Crofton
10.0 out of 10, Exceptional, (1)
"We had a great stay here with family. The house was extremely clean and everything looked new. The setup was perfect for a big group. Having two full kitchens, one on each floor, made it easy for our crew to spread out and still have their own space when they wanted it.The basement was open and worked really well for the kids to play and hang out. Even though it was winter, we still spent time outside around the fire pit, which was a nice surprise. The garage was huge and became a fun spot to...
United States
Mary K.
The price is ￥52,373
￥122,717 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Irene Hotel Reviews

Comfort Inn Yankton SD

Comfort Inn Yankton SD

10/10 Excellent
"Very clean room. Odor free."
George 3-night trip
Posted 3 days ago
Comfort Inn Yankton SD

Find out more about Irene

Search for holiday rentals in Irene on Expedia! You can easily find your home rentals, villas, holiday apartments in Irene using one of the methods below:

  • View our selection of featured holiday rentals in Irene
  • Use the map to find apartments and other holiday homes in the Irene neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Irene while they last

Look no further and take a look at our great range of rental properties in Irene!

Frequently asked questions

Can I find vacation rentals in Irene?

Yes, we offer vacation rentals near the most popular points of interest in Irene, or you can select a secluded option if you'd like a relaxing place to stay.

What's the top vacation rental in Irene?

Gavins Point Lakehouse: This vacation home rental outside of Irene is located in the mountains and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games.

What’s there to see and do in Irene?

While you're exploring the area, Fantle Memorial Park and Crockett Park are a couple of picturesque spots to get outside and enjoy nature. Mount Marty College and Mead Museum are a couple of places you'll find in the larger area.

What are vacation rentals like in Irene?

Vacation rentals are privately owned accommodations you can stay in for several days or more in Irene. Vacation rentals offer extras such as WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about cleanliness, a vacation rental can offer a sense of safety away from shared hotel elevators and lobbies packed with people while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a popular option for a small group gathering.