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Our top choices for Genessee-Moselle hotels

Front of property
Clarence Inn

Clarence Inn

Clarence Inn
2.0 star property
15.1 km from Genessee-Moselle
8.2 out of 10, Very Good, (294)
"Very nice place to stay. This is my third time staying here and I will be back again"
United States
kevin
The price is ￥15,482
￥17,301 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Clarence Inn
Lobby
Hampton Inn Lockport - Buffalo

Hampton Inn Lockport - Buffalo

Hampton Inn Lockport - Buffalo
2.5 star property
26.7 km from Genessee-Moselle
9.0 out of 10, Wonderful, (762)
"overall great experience. very nice hotel"
Canada
Edward
The price is ￥15,027
￥16,981 total
includes taxes & fees
Jan 26 - Jan 27, 2026
Hampton Inn Lockport - Buffalo
Terrace/patio
Lockport Inn & Suites

Lockport Inn & Suites

Lockport Inn & Suites
2.0 star property
29.6 km from Genessee-Moselle
9.2 out of 10, Wonderful, (1001)
"The room was really clean and the staff and house keeping was excellent. "
United States
John
The price is ￥15,441
￥17,448 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Lockport Inn & Suites
Exterior
Holiday Inn Express Amherst - Lockport by IHG

Holiday Inn Express Amherst - Lockport by IHG

Holiday Inn Express Amherst - Lockport by IHG
2.5 star property
22.8 km from Genessee-Moselle
9.2 out of 10, Wonderful, (741)
"Room was super clean. Front desk was super friendly and helpful. Breakfast buffet was great. "
Canada
Terra
The price is ￥16,065
￥18,153 total
includes taxes & fees
Jan 31 - Feb 1, 2026
Holiday Inn Express Amherst - Lockport by IHG
Exterior
Staybridge Suites West Seneca by IHG

Staybridge Suites West Seneca by IHG

Staybridge Suites West Seneca by IHG
3.0 star property
8.5 km from Genessee-Moselle
9.0 out of 10, Wonderful, (868)
"So extremely clean, quiet, spacious and a great breakfast in the morning!"
United States
Julia
The price is ￥27,295
￥31,048 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Staybridge Suites West Seneca by IHG
Restaurant
Hampton Inn Buffalo South/I-90

Hampton Inn Buffalo South/I-90

Hampton Inn Buffalo South/I-90
2.5 star property
8.9 km from Genessee-Moselle
8.6 out of 10, Excellent, (1004)
"Family friendly!"
United States
Eylem
The price is ￥18,978
￥21,589 total
includes taxes & fees
Jan 28 - Jan 29, 2026
Hampton Inn Buffalo South/I-90
Terrace/patio
Candlewood Suites Buffalo - Amherst by IHG

Candlewood Suites Buffalo - Amherst by IHG

Candlewood Suites Buffalo - Amherst by IHG
2.5 star property
9.5 km from Genessee-Moselle
8.6 out of 10, Excellent, (956)
"Good size room, very clean. Courteous staff Full size refrigerator , dishwasher, coffee pot - cutlery, and a good location. "
United States
Julia
The price is ￥14,543
￥16,543 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Candlewood Suites Buffalo - Amherst by IHG
Terrace/patio
Roycroft Inn

Roycroft Inn

Roycroft Inn
3.5 star property
22.6 km from Genessee-Moselle
9.6 out of 10, Exceptional, (847)
"Always a great stay for a Bills weekend. Love the bar. "
United States
Christine
Roycroft Inn
Terrace/patio
Home2 Suites by Hilton Amherst Buffalo

Home2 Suites by Hilton Amherst Buffalo

Home2 Suites by Hilton Amherst Buffalo
3.0 star property
10.5 km from Genessee-Moselle
8.8 out of 10, Excellent, (1001)
"Clean hotel and friendly staff."
United States
Maxine
The price is ￥19,056
￥21,676 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Home2 Suites by Hilton Amherst Buffalo
Exterior
Fairfield Inn & Suites by Marriott Buffalo Amherst/University

Fairfield Inn & Suites by Marriott Buffalo Amherst/University

Fairfield Inn & Suites by Marriott Buffalo Amherst/University
2.5 star property
10 km from Genessee-Moselle
8.8 out of 10, Excellent, (709)
"Staff at the front desk were very personable and helpful. The room was spacious and had great amenities. "
Canada
Kristin
The price is ￥17,827
￥20,279 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Fairfield Inn & Suites by Marriott Buffalo Amherst/University
Exterior
CenterWay Hotel Tonawanda

CenterWay Hotel Tonawanda

CenterWay Hotel Tonawanda
2.0 star property
10.8 km from Genessee-Moselle
7.8 out of 10, Good, (1006)
" THIS is a good hotel."
United States
Chia Hung
The price is ￥10,910
￥12,410 total
includes taxes & fees
Jan 1 - Jan 2, 2026
CenterWay Hotel Tonawanda
Couples treatment rooms, body treatments, hot stone massages
The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton

The Mosey Buffalo Williamsville, Tapestry Collection by Hilton
4.0 star property
7.7 km from Genessee-Moselle
9.4 out of 10, Exceptional, (1005)
"Very clean and modern rooms. Great bar in the hotel. Overall great stay. "
United States
Rich
The price is ￥22,312
￥25,380 total
includes taxes & fees
Jan 12 - Jan 13, 2026
The Mosey Buffalo Williamsville, Tapestry Collection by Hilton
View from property
Courtyard by Marriott Buffalo Amherst/University

Courtyard by Marriott Buffalo Amherst/University

Courtyard by Marriott Buffalo Amherst/University
3.0 star property
8.6 km from Genessee-Moselle
8.2 out of 10, Very Good, (1004)
"Very comfy beds and pleasant front desk staff. "
Canada
Crystal
The price is ￥17,147
￥19,505 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Courtyard by Marriott Buffalo Amherst/University
Front of property - evening/night
Country Inn & Suites by Radisson, Buffalo South I-90, NY

Country Inn & Suites by Radisson, Buffalo South I-90, NY

Country Inn & Suites by Radisson, Buffalo South I-90, NY
2.5 star property
8.5 km from Genessee-Moselle
8.2 out of 10, Very Good, (1294)
"Friendly staff and appreciated how long the continental breakfast was available."
United States
Elizabeth
The price is ￥19,141
￥21,773 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Country Inn & Suites by Radisson, Buffalo South I-90, NY
Property amenity
Staybridge Suites Buffalo-Amherst by IHG

Staybridge Suites Buffalo-Amherst by IHG

Staybridge Suites Buffalo-Amherst by IHG
3.0 star property
10.1 km from Genessee-Moselle
9.0 out of 10, Wonderful, (1005)
"The breakfast was amazing, the staff are extremely caring and friendly"
Canada
Sarah
The price is ￥19,808
￥22,531 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Staybridge Suites Buffalo-Amherst by IHG
Hypo-allergenic bedding, in-room safe, desk, blackout drapes
Hampton Inn East Aurora

Hampton Inn East Aurora

Hampton Inn East Aurora
2.5 star property
23.2 km from Genessee-Moselle
9.4 out of 10, Exceptional, (986)
"Great place! easy parking , clean and quiet, nice breakfast and great staff"
United States
Mark
The price is ￥19,056
￥21,676 total
includes taxes & fees
Jan 29 - Jan 30, 2026
Hampton Inn East Aurora
Restaurant
Homewood Suites by Hilton Buffalo/Amherst

Homewood Suites by Hilton Buffalo/Amherst

Homewood Suites by Hilton Buffalo/Amherst
3.0 star property
8.7 km from Genessee-Moselle
9.0 out of 10, Wonderful, (1000)
"Very nice place to stay. It is clean, great staff, and pool. "
United States
Philip
The price is ￥20,137
￥22,906 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Homewood Suites by Hilton Buffalo/Amherst
Exterior
La Quinta Inn & Suites by Wyndham Lackawanna

La Quinta Inn & Suites by Wyndham Lackawanna

La Quinta Inn & Suites by Wyndham Lackawanna
3.0 star property
10.1 km from Genessee-Moselle
6.4 out of 10, (1001)
"Hotel and breakfast were very nice"
United States
Elizabeth
The price is ￥12,362
￥14,061 total
includes taxes & fees
Jan 6 - Jan 7, 2026
La Quinta Inn & Suites by Wyndham Lackawanna
Exterior
Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY
2.5 star property
10 km from Genessee-Moselle
9.4 out of 10, Exceptional, (2002)
"Great room, staff, breakfast, and pool- would definitely stay here again!"
United States
Madison
The price is ￥16,542
￥18,817 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Hampton Inn Buffalo - Amherst, NY
Staircase
The Edward Hotel

The Edward Hotel

The Edward Hotel
3.0 star property
Elmwood Village, 4.3 km from Genessee-Moselle
9.6 out of 10, Exceptional, (219)
"Great location in Elmwood Village area. Clean room with gas fireplace. Self check- in was easy with staff provided instructions. Many food options within walking distance. "
United States
Jon
The Edward Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Genessee-Moselle

Find the best Genessee-Moselle areas and neighborhoods for the activities you enjoy most.
Buffalo showing a city, a monument and a skyscraper

Downtown Buffalo

Experience the city's rich culture with visits to the oldest urban parks system in the US, Albright–Knox Art Gallery, and Shea's Performing Arts Center. Enjoy annual festivals and explore nearby universities.

Buffalo Theater District

Theaters, live music, and restaurants highlight some notable features of Buffalo Theater District. Make a stop by Shea's Performing Arts Center or Chippewa District while you're visiting, and jump aboard the metro at Fountain Plaza Station or Lafayette Square Station to get around town.

Elmwood Village

Travelers come to Elmwood Village for its live music, and you can see top attractions like Blue Sky Mausoleum and Ujima Theatre Company while you're in town.

Delaware Park showing a lake or waterhole

North Buffalo

The live music and zoo are just a few things visitors like about North Buffalo. Buffalo Zoo and Buffalo History Museum are worthwhile spots to check out, and you can hop on the metro at Amherst Street Station or Lasalle Station to get around the larger area.

Allentown

Embracing bohemian and hipster culture, this artistic community offers vibrant nightlife, diverse dining, and antique shopping. Explore the Allentown Historic District, including the renowned Kleinhans Music Hall.

Top Genessee-Moselle Hotel Reviews

La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

10/10 Excellent
"Best beds"
Samuel 2-night trip
Posted 1 day ago
La Quinta Inn by Wyndham Buffalo Airport

Frequently asked questions

What's it like in Genessee-Moselle?
You'll be sure to have fun visiting Buffalo's Genessee-Moselle neighborhood.
If I need to cancel my hotel reservation in Genessee-Moselle, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best deals available in Genessee-Moselle.
Where can I learn more about changing or cancelling my trip to Genessee-Moselle?
For more information about changing or cancelling your trip to Genessee-Moselle, click here.
What is there to do around this Buffalo neighborhood?
Iron Island Museum, Buffalo Museum of Science, and Buffalo Central Terminal are just a few of the places to visit in and around Genessee-Moselle. Broadway Market and Buffalo Fire Historical Society are also worth a visit when you're out sightseeing in Buffalo.