Dona Ana Vacation Rentals

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Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for Dona Ana vacation rentals

Outdoor dining
Studio w/queen bed, pets ok, 3 min to Farmer's mkt

Mobile Home in Las Cruces

Studio w/queen bed, pets ok, 3 min to Farmer's mkt
10.0 out of 10, Exceptional, (2)
"Wonderful property. Peace and quiet. Lots of wildlife. Worth the unpaved road to reach the property."
United States
Robert T.
The price is ￥11,899
￥28,394 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Studio w/queen bed, pets ok, 3 min to Farmer's mkt
Terrace/patio
4 Bedroom Contemporary Model Home

Vacation Home in Las Cruces

4 Bedroom Contemporary Model Home
9.2 out of 10, Wonderful, (31)
"Easy and close to campus. Nice home!"
United States
Casey T.
The price is ￥11,743
￥39,711 total
includes taxes & fees
Jan 3 - Jan 4, 2026
4 Bedroom Contemporary Model Home
TV
2 bd w/lrg fenced yard 3 mins from farmers market

Apartment in Las Cruces

2 bd w/lrg fenced yard 3 mins from farmers market
10.0 out of 10, Exceptional, (2)
"Excellent little house with an amazing back yard!! This house has been completely refurbished with new furniture and appliances! If you’re looking for something with southwest style, you’ll appreciate the tile work in the kitchen and decorations throughout. The neighborhood has lots of culture with art and murals on walls and buildings. Make sure to go to the park nearby and visit The Bean coffee shop (got a red chile latte) and La Nueva Casita Café for a good local New Mexican meal. "
United States
Angelina M.
The price is ￥14,718
￥33,300 total
includes taxes & fees
Jan 9 - Jan 10, 2026
2 bd w/lrg fenced yard 3 mins from farmers market
Fridge, microwave, oven, stovetop
Downtown Midcentury Studio+ 3 mins to Farmer`s Mkt

Apartment in Las Cruces

Downtown Midcentury Studio+ 3 mins to Farmer`s Mkt
10.0 out of 10, Exceptional, (1)
"We were unable to actually stay in the apartment since we came down with the flu right before our trip. However, communication with the host was easy, they were very responsive, and I will absolutely stay at one of their properties next time we are in Las Cruces. "
United States
Claire Z.
The price is ￥12,369
￥29,455 total
includes taxes & fees
Dec 29 - Dec 30
Downtown Midcentury Studio+ 3 mins to Farmer`s Mkt
Interior
Charming 2-bedroom Casita In Mesilla Park

Vacation Home in Las Cruces

Charming 2-bedroom Casita In Mesilla Park
2.0 star property
10.0 out of 10, Exceptional, (2)
"perfect for our weekend getaway. host was friendly and provided all. the info needed. house was clean and had everything we needed perfect location "
United States
Sandra S.
The price is ￥13,809
￥28,544 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Charming 2-bedroom Casita In Mesilla Park
Living area
Beautiful little Magnolia in Las Cruses

Apartment in Las Cruces

Beautiful little Magnolia in Las Cruses
2.0 star property
8.8 out of 10, Excellent, (3)
"Quiet Clean comfortable beds at a reasonable price "
United States
Timmi M.
The price is ￥13,950
￥38,370 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Beautiful little Magnolia in Las Cruses
Fridge, microwave, oven, stovetop
2 bd/2bth near NMSU and Memorial Medical Center

Vacation Home in Las Cruces

2 bd/2bth near NMSU and Memorial Medical Center
10.0 out of 10, Exceptional, (3)
"Wonderful nights sleep says it all - w hugs waiting in the kitchen kuerig coffee , eggs , English muffins to get us started on our way 10 stars "
United States
Anita S.
The price is ￥16,596
￥40,666 total
includes taxes & fees
Dec 30 - Dec 31
2 bd/2bth near NMSU and Memorial Medical Center
Property grounds
Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio

Vacation Home in Las Cruces

Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio
10.0 out of 10, Exceptional, (6)
"Beautiful home, really enjoyed our stay. Would recommend this home to others. "
United States
Darlyn G.
The price is ￥10,568
￥27,576 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio
Interior
Centrally located Cozy RV with all the essentials in spacious secure gated area!

Mobile Home in Las Cruces

Centrally located Cozy RV with all the essentials in spacious secure gated area!
9.2 out of 10, Wonderful, (10)
"Great location and very convenient. Worked well for our stay. Clean and convenient - just whaat we needed. Host was very helpful. "
United States
Keith R.
The price is ￥7,515
￥14,595 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Centrally located Cozy RV with all the essentials in spacious secure gated area!
Interior
Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces

Vacation Home in Las Cruces

Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces
9.6 out of 10, Exceptional, (5)
"I was truly impressed with my rental. It was extremely clean, quiet, comfortable and pleasant. The price was reasonable and we enjoyed it tremendously! Thank you John and Erica!!! My son enjoyed the popcorn. Hope to be renting this again soon!"
United States
Robert M.
The price is ￥11,743
￥23,760 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces
Fridge, microwave, oven, stovetop
Beautiful and comfortable two bedroom apartment

Apartment in Las Cruces

Beautiful and comfortable two bedroom apartment
10.0 out of 10, Exceptional, (3)
"We loved the location, really easy to get to the university and the shopping areas. Great place for our family to meet and gather! We were very pleased with the location. "
United States
tyra R.
Beautiful and comfortable two bedroom apartment
2 bedrooms, desk, iron/ironing board, travel crib
2 bed with W/D, pets ok, 5 min to Farmers Market

Vacation Home in Las Cruces

2 bed with W/D, pets ok, 5 min to Farmers Market
8.0 out of 10, Very Good, (1)
"Was a bit difficult to get into the house on first. Told the key pad numbers but didn't tell us to press KWIKSET. Then, to go leave, we didn't know that we just press KWICKSET. It would have been hpful to know all of that in the initial email. In addition, the key pad is at the front door NOT the back door. "
United States
Elaine
The price is ￥14,874
￥35,062 total
includes taxes & fees
Jan 3 - Jan 4, 2026
2 bed with W/D, pets ok, 5 min to Farmers Market
Property grounds
Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis

Vacation Home in Las Cruces

Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis
2.0 star property
9.2 out of 10, Wonderful, (12)
"Great location, comfortable set up. I’d stay here again."
United States
Clay C.
The price is ￥17,191
￥33,736 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis
Interior
Vintage 80's Retro RV Experience, Back to 1985!

Mobile Home in Las Cruces

Vintage 80's Retro RV Experience, Back to 1985!
9.0 out of 10, Wonderful, (4)
"This was a great stay in a unique rv. The owners were awesome and friendly. We felt very safe in the lot and knew our vehicle wouldn't get broken into. We would definitely return and stay in one of their rvs again "
United States
Amanda L.
The price is ￥7,515
￥19,175 total
includes taxes & fees
Dec 29 - Dec 30
Vintage 80's Retro RV Experience, Back to 1985!
Interior
Cozy and Modern Home w/ King Bed and more!

Vacation Home in Las Cruces

Cozy and Modern Home w/ King Bed and more!
9.8 out of 10, Exceptional, (25)
"Great stay. The house was comfortable and cozy, and the owners were very responsive. I'll definitely reserve again on my next visit yo Las Cruces."
United States
Laura G.
The price is ￥10,177
￥31,644 total
includes taxes & fees
Dec 30 - Dec 31
Cozy and Modern Home w/ King Bed and more!
Fridge, microwave, oven, stovetop
1 bedroom near NMSU. W/D in unit/pets welcome.

Vacation Home in Las Cruces

1 bedroom near NMSU. W/D in unit/pets welcome.
10.0 out of 10, Exceptional, (1)
"Padma wa an excellent host. She answered all our questions in a timely manner. I would recommend them to family and friends. Thank you for everything. "
United States
Jason W.
The price is ￥16,910
￥36,547 total
includes taxes & fees
Jan 3 - Jan 4, 2026
1 bedroom near NMSU. W/D in unit/pets welcome.
Fridge, microwave, oven, stovetop
2 king bds/2.5 bathrooms in the heart of Downtown

Vacation Home in Las Cruces

2 king bds/2.5 bathrooms in the heart of Downtown
10.0 out of 10, Exceptional, (1)
"Great communication with host, perfect location centrally located, quiet neighborhood. Beautiful home!"
United States
Veronica M.
The price is ￥17,536
￥46,442 total
includes taxes & fees
Dec 30 - Dec 31
2 king bds/2.5 bathrooms in the heart of Downtown
Fridge, microwave, oven, stovetop
New Casita/Suite No cleaning fee.

Apartment in Las Cruces

New Casita/Suite No cleaning fee.
9.6 out of 10, Exceptional, (25)
"Great place to stop for the night. "
United States
Jenesta S.
The price is ￥16,064
￥20,807 total
includes taxes & fees
Dec 29 - Dec 30
New Casita/Suite No cleaning fee.
Fridge, microwave, oven, stovetop
Southwest Gem just minutes from White Sands National Park

Vacation Home in Las Cruces

Southwest Gem just minutes from White Sands National Park
10.0 out of 10, Exceptional, (21)
"I would stay here again. "
United States
Sara R.
The price is ￥15,499
￥42,351 total
includes taxes & fees
Dec 29 - Dec 30
Southwest Gem just minutes from White Sands National Park
Dining
Elite Casita with EV Level II Charger & Indoor Jet Tub

Mobile Home in Las Cruces

Elite Casita with EV Level II Charger & Indoor Jet Tub
10.0 out of 10, Exceptional, (2)
"Great place!!! "
United States
Tera W.
The price is ￥16,910
￥40,053 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Elite Casita with EV Level II Charger & Indoor Jet Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Dona Ana Hotel Reviews

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

10/10 Excellent
"Room is very spacious and clean. Check in staff personnel was very informative telling us about the happy hour and breakfast."
carla 1-night trip
Posted 4 days ago
Drury Inn & Suites Las Cruces

Find out more about Dona Ana

Search for holiday rentals in Dona Ana on Expedia! You can easily find your home rentals, villas, holiday apartments in Dona Ana using one of the methods below:

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Look no further and take a look at our great range of rental properties in Dona Ana!

Frequently asked questions

Are there vacation rentals in Dona Ana?

Yes, we have vacation rentals near well known local attractions in Dona Ana, or you can go with a more secluded option if you want a relaxing place to stay.

What are some of the best vacation home rentals that Dona Ana has to offer?

Las Cruces - Modern 3BR Near Downtown, Mesilla, White Sands + Backyard Oasis: Visitors like this Dona Ana vacation home rental. It offers a fireplace, a patio, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a stovetop, and a microwave, so you can cook with friends or family.

What can I see and do in Dona Ana?

Explore the area and family-friendly sights such as Museum of Nature & Science, or get out into nature at a spot like Dripping Springs Natural Area. Red Hawk Golf Club and Sonoma Ranch Golf Course are a couple of places you'll find in the larger area.

What are vacation rentals like in Dona Ana?

Vacation rentals are privately owned properties you can reserve for a couple days or more in Dona Ana. Vacation rentals offer extras like WiFi and washers and dryers to help you enjoy your stay. If you're concerned about a sanitized environment, vacation rentals can offer a sense of safety away from public hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for a small group gathering.