The Best Hotels Closest to Buffalo General Medical Center in Buffalo for 2026

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Our top choices for Buffalo General Medical Center hotels

A grand staircase with ornate woodwork and a chandelier, leading to a room with a large wooden door and a stained glass window.

A grand room with a chandelier, a fireplace, and ornate furniture.

A spacious room with a wooden floor, a fireplace, a dining area with a table and chairs, and a large rug.

A room with a red patterned sofa, wooden bookshelves, a chandelier, and a traditional wooden coffee table.

1. InnBuffalo off Elmwood

Elmwood Village, 2.3 km from Buffalo General Medical Center

Terese

￥21,791

￥25,006 total

includes taxes & fees

Nov 9 - Nov 10

A spacious room with a wooden floor, a fireplace, a dining table, and several chairs.

A traditional living room with a green sofa, a wooden coffee table with books, a blue armchair, and various potted plants.

A historic building with a prominent tower and a traditional brick facade.

A grand hallway with a wooden staircase, a chandelier, and a patterned floor.

2. Buffalo Harmony House

Allentown, 1.3 km from Buffalo General Medical Center

John

￥51,559

￥59,955 total

includes taxes & fees

Oct 13 - Oct 14

A spacious dining area with a long table, multiple chairs, a chandelier, and a fireplace.

A bedroom with a four-poster bed, a yellow sofa, a white coffee table, and a desk with a chair.

A grand staircase with a wooden handrail and a leopard print carpet, leading to a room with a large window and a door with frosted glass panels.

A living room with a fireplace, two leather armchairs, a coffee table, and a chandelier.

3. The Edward Hotel

Elmwood Village, 2.1 km from Buffalo General Medical Center

Grace

￥17,971

￥24,747 total

includes taxes & fees

Oct 26 - Oct 27

A two-story building with a white exterior, a red door, and large windows.

A hot tub with a wooden fence and a brick building in the background.

A living room with a fireplace, a chandelier, leather sofas, and a glass coffee table.

A living room with a fireplace, leather sofa, and a television mounted on the wall.

4. Buffalo Guesthouse

Allentown, 0.5 km from Buffalo General Medical Center

Jan

￥23,690

￥27,185 total

includes taxes & fees

Oct 16 - Oct 17

A modern hotel room with a large window, a sofa, a coffee table, and a TV.

A modern kitchen with a central island, bar stools, and built-in appliances.

A modern hotel lobby with a reception desk, seating area, and a large window offering a view of the city.

A hotel lobby with a seating area, dining tables, and large windows offering views of the cityscape.

5. Buffalo Marriott at LECOM HARBORCENTER

Downtown Buffalo, 2.8 km from Buffalo General Medical Center

Michael

￥36,902

￥43,083 total

includes taxes & fees

Oct 18 - Oct 19

A grand entrance with a staircase leading to a door, surrounded by lush greenery and a well-maintained garden.

A bar area with wooden furniture, a large wooden cabinet, and a clock on the wall.

A living room with a red wall, white furniture, a fireplace, and a large abstract painting.

A pool table in a room with dark walls, large windows, and green upholstered chairs.

6. The Mansion On Delaware Ave

Allentown, 1 km from Buffalo General Medical Center

Marilyn

￥28,045

￥32,182 total

includes taxes & fees

Oct 18 - Oct 19

A breakfast buffet with various food items and beverages, a large window with a view of buildings, and a patterned floor.

A heated outdoor swimming pool with lounge chairs and a bar area, surrounded by brick walls and a balcony with decorative lighting.

A circular fire pit with a metal railing, surrounded by a stone base, set on a tiled patio with a city skyline in the background.

7. Curtiss Hotel, an Ascend Collection Hotel

Buffalo Theater District, 1.5 km from Buffalo General Medical Center

John

￥41,580

￥48,544 total

includes taxes & fees

Nov 10 - Nov 11

A spacious lobby with a large sofa, a coffee table, and potted plants. There is a decorative wall with a painting and a large window providing natural light.

A hotel dining area with multiple tables and chairs, a reception desk, and framed pictures on the walls.

A compact kitchen with wooden cabinets, a black refrigerator, a microwave, and a coffee maker.

A multi-story hotel with a modern facade, large windows, and a covered entrance area.

8. Wyndham Garden Buffalo Downtown

Downtown Buffalo, < 0.1 km from Buffalo General Medical Center

Julian

￥24,086

￥28,122 total

includes taxes & fees

Oct 13 - Oct 14

A spacious lobby with modern furniture, large windows, and a high ceiling with exposed beams.

An outdoor patio area with seating, a fire feature, and a glass-enclosed space with greenery.

A spacious lobby with a stone fireplace, comfortable seating, large windows, and a modern design.

The Westin hotel entrance with a glass facade and a sign indicating it's now open.

9. The Westin Buffalo

Buffalo Theater District, 1.4 km from Buffalo General Medical Center

Sarah

￥37,519

￥43,804 total

includes taxes & fees

Oct 18 - Oct 19

A modern outdoor patio with stone walls, a fire feature, and outdoor furniture.

A modern indoor swimming pool with clear water, lounge chairs, and a large wall with a textured pattern.

A modern lobby with a wooden reception desk, comfortable seating, and a decorative wall with shelves.

A multi-story hotel with a modern design, featuring a prominent entrance with a covered walkway and a courtyard.

10. Courtyard Buffalo Downtown / Canalside

Downtown Buffalo, 2.7 km from Buffalo General Medical Center

Diana

￥32,161

￥37,547 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, desk, chair, TV, and a bathroom with a sink and mirror.

A modern gym with cardio machines, a mirrored wall, and a blue accent wall.

A modern hotel lobby with a round coffee table, two grey armchairs, a TV, and a reception desk.

A hotel lobby with a curved reception desk, a chandelier, a seating area with leather chairs, and a tiled floor.

11. Best Western on the Avenue

Allentown, 0.8 km from Buffalo General Medical Center

John

￥24,081

￥28,115 total

includes taxes & fees

Oct 18 - Oct 19

A hotel with a prominent red sign, large windows, and a parking lot with multiple cars.

A modern living room with a fireplace, comfortable seating, and a herringbone-patterned wall.

A breakfast buffet with various pastries, fruits, and bread.

An indoor swimming pool with clear blue water, a metal pool ladder, and a seating area with tables and chairs.

12. Hampton Inn & Suites Buffalo Downtown

Buffalo Theater District, 1.5 km from Buffalo General Medical Center

Gerald D

￥26,778

￥31,264 total

includes taxes & fees

Oct 18 - Oct 19

An indoor swimming pool with tiled walls, a lifeguard chair, and a pool ladder.

A lobby area with a reception desk, seating arrangements, a coffee station with beverages and snacks, and a decorative wall with a fireplace.

A modern lobby with a leather sofa, a fireplace, and a television mounted on the wall.

A hotel room with a bed, a desk, a chair, and a view of a cityscape through large windows.

13. Hilton Garden Inn Buffalo Downtown

Buffalo Theater District, 1.7 km from Buffalo General Medical Center

Mercedes

￥25,163

￥29,378 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, a TV, a desk, a chair, and a sofa.

A modern hotel room with a wooden dresser, a flat-screen TV, a kitchenette, a blue sofa, and a small table.

A gym with exercise equipment, a mirror, and a television.

A coffee station with two coffee makers, a coffee dispenser, and various coffee cups and containers.

14. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Theater District, 1.3 km from Buffalo General Medical Center

Charles

￥23,588

￥27,538 total

includes taxes & fees

Oct 18 - Oct 19

A long, ornate hallway with marble walls and a patterned floor, leading to a set of double doors.

A modern hotel room with a fireplace, a flat-screen TV, a sofa, and a bed.

A spacious lobby with a central seating area, large columns, and a chandelier.

The facade of Hotel at the Lafayette with a classic architectural style, large windows, and a prominent entrance.

15. Hotel at the Lafayette Trademark Collection by Wyndham

Buffalo Theater District, 1.8 km from Buffalo General Medical Center

Angela

￥24,492

￥28,596 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel with a curved glass facade, a central staircase, and a well-lit interior.

A hotel room with a large bed, a TV mounted on the wall, a city view through the window, and a wooden shelf.

A modern bar area with seating, a counter with bottles, and a large window.

A conference room with two chairs and a table, large windows with a city view, and a patterned carpet.

16. Embassy Suites Buffalo

Buffalo Theater District, 1.5 km from Buffalo General Medical Center

Michelle

￥28,123

￥32,834 total

includes taxes & fees

Oct 25 - Oct 26

An indoor swimming pool with clear glass walls, a wooden wall, and a view of buildings outside.

A hotel room with a sofa set, a small coffee table, a TV, and a lamp.

A Hyatt Regency hotel with a large entrance, a statue of a bull, and a landscaped garden with various plants.

A restaurant with multiple tables and chairs, large windows with curtains, and a chandelier.

17. Hyatt Regency Buffalo / Hotel and Conference Center

Buffalo Theater District, 1.6 km from Buffalo General Medical Center

Joseph

￥21,678

￥25,310 total

includes taxes & fees

Oct 25 - Oct 26

A lobby with a staircase, seating area, and a view of the outdoors.

A hotel with a classic brick facade, a glass entrance, and flags.

A bathroom with a toilet, sink, and shower curtain.

A reception area with a marble wall, a reception desk with glass panels, a clock, and a television mounted on the wall.

18. Lenox Hotel and Suites

Allentown, 0.8 km from Buffalo General Medical Center

Thomas

￥16,140

￥18,521 total

includes taxes & fees

Oct 27 - Oct 28

A rooftop terrace with wicker furniture, a bar area, and a view of the cityscape.

A modern hotel with a glass facade, multiple floors, and a prominent 'Aloft' sign.

A bar area with a circular bar counter, multiple hanging light fixtures, and bar stools.

A modern living room with a large window, a flat-screen TV, a sofa, a coffee table, and a patterned rug.

19. Aloft by Marriott Buffalo Downtown

Buffalo Theater District, 1 km from Buffalo General Medical Center

Anthony T

￥34,702

￥40,513 total

includes taxes & fees

Nov 8 - Nov 9

A dining area with a wooden table set for four, surrounded by chairs. There is a kitchen area with cabinets and appliances in the background.

A modern living room with a sectional sofa, a dining area, and a kitchen in the background.

A bedroom with a bed, bedside lamps, a nightstand, a window with curtains, and wall art.

A kitchen with wooden cabinets, a dishwasher, and a dining area with a table and chairs.

20. 4 Mi to Dtwn: Family Home in Buffalo

Masten Park, 1.4 km from Buffalo General Medical Center

￥47,018

￥83,287 total

includes taxes & fees

Oct 13 - Oct 14

View all properties

Compare popular hotels close to Buffalo General Medical Center

Property	Star rating	Guest rating
InnBuffalo off Elmwood	10.0 Exceptional 224 reviews	View
Buffalo Harmony House	10.0 Exceptional 56 reviews	View
The Edward Hotel	9.6 Exceptional 268 reviews	View
Buffalo Guesthouse	9.4 Exceptional 221 reviews	View
Buffalo Marriott at LECOM HARBORCENTER	9.4 Exceptional 984 reviews	View

Top Buffalo General Medical Center Hotel Reviews

The Mansion On Delaware Ave

8/10 Good

"Wonderful staff and wonderful building. My wife felt the breakfasts were some of the best breakfast dishes she’s had at any hotel or cafe. The reason I rated 4 instead of 5 stars is because the mattress wasn’t particularly comfortable and the soap/shampoo didn’t feel like it totally cleaned. Location gave excellent walking, running, and driving access, and free parking made having a car in the city very easy. I would stay here again without second thought!"

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

10/10 Excellent

"The room was very clean and nice. Walking distance to just about most of the places we wanted to visit a good place to stay."

Buffalo Guesthouse

10/10 Excellent

"Comfy beds and friendly environment."

Lenox Hotel and Suites

10/10 Excellent

"Enjoyed our stay"

Cozy & Modern Victorian in Historic Allentown, Buffalo

10/10 Excellent

"Brandon's home was the absolute perfect location for a long weekend in Buffalo. We were able to walk just steps to one of our favorite restaurants (Gabriel's Gate), and all the bars and markets on Allen Street/Elmwood Ave.. The house had everything we needed and was decorated/furnished so nicely. The beds were super comfy, I slept like baby. The backyard garden was an oasis and I worked for two days from the table in the backyard, wifi was great! The neighbor was very nice too, which is par for the course in Buffalo. Love this city!! Go Bills."

Hilton Garden Inn Buffalo Downtown

8/10 Good

"I didn't like that it was cashless. Also the lobby coffee, while cheap, was not good."

Hampton Inn & Suites Buffalo Downtown

10/10 Excellent

"Clean Comfortable Good breakfast"

The Westin Buffalo

10/10 Excellent

"."

Curtiss Hotel, an Ascend Collection Hotel

10/10 Excellent

"Loved it, we actually rerouted our return trip home to stay here again :)"

Frequently asked questions

What's the area like around Buffalo General Medical Center?

Buffalo General Medical Center is located in a historic area of Buffalo known for its popular theater scene. If you're looking for a convenient place to stay, check out the 75 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Buffalo General Medical Center?

Adjacent to Buffalo General Medical Center, Wyndham Garden Buffalo Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices close by include Hyatt Regency Buffalo / Hotel and Conference Center and Buffalo Guesthouse.

How many hotels should I expect to find near Buffalo General Medical Center?

Expedia has 75 hotels and other accommodations within a mile from Buffalo General Medical Center.

If I need to cancel the hotel reservation for my stay near Buffalo General Medical Center, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best deals near Buffalo General Medical Center.

Where can I learn more about changing or cancelling my trip in the area near Buffalo General Medical Center?

For more information about updating your stay near Buffalo General Medical Center or cancelling it, go to https://www.expedia.com/service/.

What can I see and do near Buffalo General Medical Center?

Buffalo Museum of Science, Buffalo and Erie County Naval and Military Park, and Buffalo AKG Art Museum feature a variety of fascinating exhibits to see while you're in town. Statler Tower, Buffalo Central Terminal, and Richardson Olmsted Complex are monuments to see when you're exploring the area around Buffalo General Medical Center. You can catch a show at Kleinhans Music Hall, Town Ballroom, and Road Less Traveled Productions.

How can I get to Buffalo General Medical Center?

With so many choices for transportation, seeing all of the area near Buffalo General Medical Center is simple. You can access metro transit at Fountain Plaza Station, Lafayette Square Station, and Church Station. If you're hopping a train into the city, Buffalo-Exchange Street Station is the closest stop to Downtown Buffalo.

Find hotels near Buffalo General Medical Center, Buffalo from ￥18,521

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

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Our top choices for Buffalo General Medical Center hotels

1. InnBuffalo off Elmwood

2. Buffalo Harmony House

3. The Edward Hotel

4. Buffalo Guesthouse

5. Buffalo Marriott at LECOM HARBORCENTER

6. The Mansion On Delaware Ave

7. Curtiss Hotel, an Ascend Collection Hotel

8. Wyndham Garden Buffalo Downtown

9. The Westin Buffalo

10. Courtyard Buffalo Downtown / Canalside

11. Best Western on the Avenue

12. Hampton Inn & Suites Buffalo Downtown

13. Hilton Garden Inn Buffalo Downtown

14. Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

15. Hotel at the Lafayette Trademark Collection by Wyndham

16. Embassy Suites Buffalo

17. Hyatt Regency Buffalo / Hotel and Conference Center

18. Lenox Hotel and Suites

19. Aloft by Marriott Buffalo Downtown

20. 4 Mi to Dtwn: Family Home in Buffalo

Compare popular hotels close to Buffalo General Medical Center

Top Buffalo General Medical Center Hotel Reviews

The Mansion On Delaware Ave

Holiday Inn Express & Suites Buffalo Downtown - Medical CTR by IHG

Buffalo Guesthouse

Lenox Hotel and Suites

Cozy & Modern Victorian in Historic Allentown, Buffalo

Hilton Garden Inn Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

The Westin Buffalo

Curtiss Hotel, an Ascend Collection Hotel

Frequently asked questions