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Compare hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

32-inch LCD TV with digital channels, TV
Lewis and Clark Resort

Lewis and Clark Resort

2.5 star property
Yankton
8.8 out of 10, Excellent, (281)
"Beautiful view, easy check in, and spacious accommodations! We loved our stay and can’t wait to come back!"
United States
Jessica
The price is ￥13,936
￥14,731 total
includes taxes & fees
Dec 1 - Dec 2
Lewis and Clark Resort
Indoor pool
Red Roof Inn Vermillion - U of South Dakota

Red Roof Inn Vermillion - U of South Dakota

2.0 star property
Vermillion
8.0 out of 10, Very Good, (421)
"I like the size of the rooms and very clean. They could use some better pillows."
United States
Tabatha L
The price is ￥12,355
￥13,742 total
includes taxes & fees
Dec 1 - Dec 2
Red Roof Inn Vermillion - U of South Dakota
Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (Walk-in Shower;with Sofabed) | In-room safe, laptop workspace, iron/ironing board, WiFi
Best Western Vermillion Inn

Best Western Vermillion Inn

2.5 star property
Vermillion
8.8 out of 10, Excellent, (556)
"Best place I’ve stayed in Vermillion. "
United States
Celeste
The price is ￥15,014
￥16,633 total
includes taxes & fees
Dec 7 - Dec 8
Best Western Vermillion Inn
Lobby
Comfort Inn Yankton SD

Comfort Inn Yankton SD

2.5 star property
Yankton
8.8 out of 10, Excellent, (658)
"Affordable with very clean, comfortable rooms, super friendly staff and a nice breakfast. "
United States
Roberta
The price is ￥13,980
￥15,509 total
includes taxes & fees
Dec 14 - Dec 15
Comfort Inn Yankton SD
Exterior
Econo Lodge Inn & Suites

Econo Lodge Inn & Suites

2.0 star property
Yankton
7.2 out of 10, Good, (703)
"We enjoyed our stay. "
United States
Patricia
The price is ￥11,301
￥12,597 total
includes taxes & fees
Nov 30 - Dec 1
Econo Lodge Inn & Suites
Exterior
Best Western Kelly Inn

Best Western Kelly Inn

2.5 star property
Yankton
8.0 out of 10, Very Good, (646)
"This was the perfect hotel for my family to stay in for a wedding. We enjoyed the breakfast, pool, and attached restaurant. I would stay there again."
United States
Lisa
The price is ￥15,325
￥16,971 total
includes taxes & fees
Nov 30 - Dec 1
Best Western Kelly Inn
Lobby
Fairfield Inn & Suites by Marriott Yankton

Fairfield Inn & Suites by Marriott Yankton

2.5 star property
Yankton
9.4 out of 10, Exceptional, (150)
"Great place to stay "
United States
Elizabeth
The price is ￥18,613
￥20,546 total
includes taxes & fees
Nov 30 - Dec 1
Fairfield Inn & Suites by Marriott Yankton
Lobby
Prairie Inn

Prairie Inn

2.0 star property
Vermillion
7.0 out of 10, Good, (334)
"Average room with easy check in and check out."
United States
Robyn
The price is ￥8,896
￥9,670 total
includes taxes & fees
Nov 28 - Nov 29
Prairie Inn
Room, 2 Queen Beds, Non Smoking | Desk, blackout drapes, free WiFi, bed sheets
Yankton Inn

Yankton Inn

2.0 star property
Yankton
7.4 out of 10, Good, (269)
"Good stay, Clean room."
United States
Jayson
The price is ￥12,631
￥14,043 total
includes taxes & fees
Nov 30 - Dec 1
Yankton Inn
Restaurant
Holiday Inn Express & Suites Yankton by IHG

Holiday Inn Express & Suites Yankton by IHG

2.5 star property
Yankton
9.2 out of 10, Wonderful, (413)
"Hope was amazing at check in. She did a great job welcoming us. "
United States
Zachary
The price is ￥14,890
￥17,279 total
includes taxes & fees
Nov 30 - Dec 1
Holiday Inn Express & Suites Yankton by IHG
Breakfast meal
Holiday Inn Express Hotel & Suites Vermillion by IHG

Holiday Inn Express Hotel & Suites Vermillion by IHG

2.5 star property
Vermillion
8.4 out of 10, Very Good, (389)
"Clean, friendly staff"
United States
Neenah J
The price is ￥14,890
￥16,499 total
includes taxes & fees
Dec 24 - Dec 25
Holiday Inn Express Hotel & Suites Vermillion by IHG
Suite, 1 King Bed, Non Smoking | Premium bedding, individually furnished, desk, laptop workspace
Cobblestone Inn & Suites - Hartington

Cobblestone Inn & Suites - Hartington

2.5 star property
Hartington
9.2 out of 10, Wonderful, (301)
"Very kind staff and check in hostess when so helpful. "
United States
Lisa
The price is ￥16,891
￥19,595 total
includes taxes & fees
Nov 24 - Nov 25
Cobblestone Inn & Suites - Hartington
Basic Single Room | Free WiFi
The Historic Argo Hotel

The Historic Argo Hotel

3.0 star property
Crofton
The price is ￥29,561
￥33,109 total
includes taxes & fees
Nov 24 - Nov 25
The Historic Argo Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Helena Hotel Reviews

Comfort Inn Yankton SD

Comfort Inn Yankton SD

10/10 Excellent
"We scored a third floor room which means quieter. The staff is always helpful and courteous"
Rodney 3-night trip
Posted 4 days ago
Comfort Inn Yankton SD

Frequently asked questions

Where is the best place to stay in St. Helena?
Located 9.7 mi (15.6 km) from the heart of St. Helena, Comfort Inn Yankton SD is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Best Western Kelly Inn and Best Western Vermillion Inn. See all available top hotels, or vacation rentals in St. Helena.
What are some of the best vacation rentals in St. Helena?
Gavins Point Lakehouse: You might want to consider this vacation home rental near St. Helena, which is located in the mountains and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 5 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in St. Helena.
If I need to cancel my hotel reservation in St. Helena, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in St. Helena.
Where can I learn more about changing or cancelling my trip to St. Helena?
To find more details about changing or cancelling your trip to St. Helena, go to https://www.expedia.com/service/.
How is it to stay in St. Helena?
Travelers to St. Helena will find plenty to explore and enjoy. There are 105 hotels and other accommodations in the surrounding area. Find out more about St. Helena.
What should I do while I'm visiting St. Helena?
A favorite place to visit is Missouri River. You'll also find Chief White Crane Recreation Area and Clay County Park in the area. Check out what more to see and do in Expedia's St. Helena guide.
What's the weather like in St. Helena?
The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 26°F. The snowiest months in St. Helena are January, December, October, and March, with each month seeing an average of 8 inches of snowfall.

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