Find hotels near South Mississippi County Regional Medical Center, Osceola from ￥11,528

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Dec 26 - Dec 27
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Our top choices for South Mississippi County Regional Medical Center hotels

Exterior
Holiday Inn Osceola by IHG

Holiday Inn Osceola by IHG

Holiday Inn Osceola by IHG
3.0 star property
6.4 km from South Mississippi County Regional Medical Center
9.0 out of 10, Wonderful, (17)
"The hotel was perfect for our two night stay while we were moving. There is a restaurant connected to the hotel that provided a nice buffet breakfast. The beds were very comfortable. "
United States
Cynthia Beth
The price is ￥17,777
￥20,532 total
includes taxes & fees
Jan 23 - Jan 24, 2026
Holiday Inn Osceola by IHG
Lobby
Days Inn & Suites by Wyndham Osceola AR

Days Inn & Suites by Wyndham Osceola AR

Days Inn & Suites by Wyndham Osceola AR
2.0 star property
6.1 km from South Mississippi County Regional Medical Center
6.4 out of 10, (365)
"The staff was very helpful and friendly. "
United States
Neil
The price is ￥9,979
￥11,528 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Days Inn & Suites by Wyndham Osceola AR
Restaurant
The Louis Hotel

The Louis Hotel

The Louis Hotel
4.0 star property
15.7 km from South Mississippi County Regional Medical Center
9.6 out of 10, Exceptional, (50)
"Beautiful property and very attentive staff-not much to do in this quaint little village, but that's exactly what we wanted. Walked to the cafe for dinner, nightcaps at the hotel bar (beautiful), had a great restful nights sleep, and then we walked back to the cafe for a wonderful brunch the next morning. The town is an oasis in the middle of nowhere!"
United States
David
The price is ￥32,203
￥36,067 total
includes taxes & fees
Jan 26 - Jan 27, 2026
The Louis Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Mississippi County Regional Medical Center Hotel Reviews

Deerfield Inn By Capital O Blytheville AR I55

Deerfield Inn By Capital O Blytheville AR I55

10/10 Excellent
"Air conditioning and heating worked. Lots of hot water. This hotel needs to update many of the room fixtures, microwave, refrigerator, exterior door did not close good with gap showing on bottom. First place I have stayed that was dusty and dirty on furniture and counters. "
BELINDA 1-night trip
Posted 5 days ago
Deerfield Inn By Capital O Blytheville AR I55

Hotels near other South Mississippi County Regional Medical Center attractions

Florida Park

Florida Park is just one of the places to see in Osceola, so why not enjoy the other things to explore during your travels? You can enjoy the restaurants while in the area.
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Osceola Branch Mississippi County Library

After visiting Osceola Branch Mississippi County Library, make a plan to see the other sights and activities in Osceola. You can enjoy the restaurants while in the area.
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Frequently asked questions

What's the area like around South Mississippi County Regional Medical Center?
South Mississippi County Regional Medical Center is located in Osceola. Travelers like this welcoming area for its restaurants. If you're looking for a convenient place to stay, check out the 6 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay close to South Mississippi County Regional Medical Center?
Holiday Inn Osceola by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 4 mi (6.4 km) from South Mississippi County Regional Medical Center. Other good options within a few miles include Days Inn & Suites by Wyndham Osceola AR and Roadside Inn.
How many hotels should I expect to find close to South Mississippi County Regional Medical Center?
Expedia has 6 hotels and other accommodations within a mile from South Mississippi County Regional Medical Center.
If I need to cancel the hotel reservation for my stay near South Mississippi County Regional Medical Center, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and get a refund within 24 hours of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to get the top deals on offer near South Mississippi County Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near South Mississippi County Regional Medical Center?
For more information about picking new dates or cancelling your stay near South Mississippi County Regional Medical Center, go to https://www.expedia.com/service/.