A valley with a town nestled between hills, a winding road, and distant mountains.

Find Luxury Hotels in Santee, CA

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Check availability on Santee Luxury Hotels

Tonight
Sep 18 - Sep 19
Tomorrow
Sep 19 - Sep 20
This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

Our top choices for Santee luxury hotels

1. Sycuan Casino Resort

Sycuan Casino Resort
El Cajon
¥13,648
¥16,896 total
includes taxes & fees
Oct 15 - Oct 16
Sycuan Casino Resort

2. Jamul Casino Resort

Jamul Casino Resort
Jamul
¥29,475
¥32,496 total
includes taxes & fees
Sep 28 - Sep 29
Jamul Casino Resort

3. San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
Mission Valley
¥29,475
¥33,880 total
includes taxes & fees
Sep 20 - Sep 21
San Diego Marriott Mission Valley

4. Lafayette Hotel & Club

Lafayette Hotel & Club
University Heights
¥42,574
¥48,936 total
includes taxes & fees
Sep 28 - Sep 29
Lafayette Hotel & Club

5. Viejas Casino & Willows Hotel

Viejas Casino & Willows Hotel
Alpine
  • Alpine casino resort offers luxury pillowtop beds, full-service spa with couples treatments, and poolside relaxation.
¥17,427
¥21,945 total
includes taxes & fees
Sep 21 - Sep 22
Viejas Casino & Willows Hotel

6. San Diego Mission Bay Resort

San Diego Mission Bay Resort
Mission Bay
¥38,832
¥52,883 total
includes taxes & fees
Oct 19 - Oct 20
San Diego Mission Bay Resort

7. DoubleTree by Hilton San Diego - Hotel Circle

DoubleTree by Hilton San Diego - Hotel Circle
Mission Valley
¥19,054
¥21,902 total
includes taxes & fees
Sep 27 - Sep 28
DoubleTree by Hilton San Diego - Hotel Circle

8. Hyatt Regency La Jolla

Hyatt Regency La Jolla
University City
¥33,061
¥43,847 total
includes taxes & fees
Oct 18 - Oct 19
Hyatt Regency La Jolla

9. Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
University City
¥30,356
¥39,335 total
includes taxes & fees
Sep 27 - Sep 28
Embassy Suites by Hilton San Diego La Jolla

10. Sheraton San Diego Resort

Sheraton San Diego Resort
Harbor Island
¥26,356
¥38,182 total
includes taxes & fees
Sep 27 - Sep 28
Sheraton San Diego Resort
View all properties

Top Santee Hotel Reviews

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"Clean"
Rebecca 2-night trip
Posted less than an hour ago
Wyndham San Diego Bayside
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"Great stay. Minutes from petco. Did not have to drive anywhere, super convenient!"
Angelica 1-night trip
Posted less than an hour ago
Hard Rock Hotel San Diego
Paradise Point Resort & Spa

Paradise Point Resort & Spa

10/10 Excellent
"My s"
Trinidad 2-night trip
Posted 1 hour ago
Paradise Point Resort & Spa
California Suites Hotel

California Suites Hotel

8/10 Good
"Parking"
Steve 1-night trip
Posted 1 hour ago
California Suites Hotel
The Dana on Mission Bay

The Dana on Mission Bay

8/10 Good
"Another of my go to hotels when fishing out of seaforth. Right across the street from the landing. Rooms are clean and nice. Parking is tight though. They need bigger stalls."
michael 1-night trip
Posted 2 hours ago
The Dana on Mission Bay
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

10/10 Excellent
"We had a perfect stay at the Manchester Grant Hyatt in SD! The location can't be beat if you're looking for something near the water, but still walkable in the Gaslamp Quarter - it's about a 10 minute walk to Petco Park, and you're steps away from Sea Port Village's establishments, and the USS Midway Museum. This location is great not only for business trips, but also a quick staycation or romantic getaway with a loved one - I will say, I believe this hotel is geared more towards adults or young professionals. Not to say that the hotel isn't family friendly in general, but the atmosphere and ammenities definitely lean more towards the adult crowd as opposed to something that a family with children would enjoy. Aside from this, our room was perfect, the Balmain ammenities were incredible, the "Top of the Hyatt" Bar was also amazing - the only bar in SD that is 40 stories high (guests get a $15 credit at the bar per night, along with a laundry list of other guest-exclusive perks & discounts at other restaurants, bars, spas, even the Old Town Trolley which is a quick 5 minute walk outside the hotel :) HIGHLY recommending this place doesn't come close to how great our stay was here!"
Micaela 1-night trip
Posted 3 hours ago
Manchester Grand Hyatt San Diego
The Sofia Hotel

The Sofia Hotel

10/10 Excellent
"Would definitely stay here again"
Mark 4-night trip
Posted 3 hours ago
The Sofia Hotel
Sheraton San Diego Resort

Sheraton San Diego Resort

10/10 Excellent
"Specifically the check-in staff was super helpful upon arrival !"
Michael 5-night trip
Posted 3 hours ago
Sheraton San Diego Resort
Best Western Seven Seas

Best Western Seven Seas

8/10 Good
"Close to freeway and reasonably priced with free parking"
Benjamin 1-night trip
Posted 4 hours ago
Best Western Seven Seas

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Santee?
Use Expedia to help you arrange a flight to San Diego, CA (SEE-Gillespie Field) airport or San Diego, CA (MYF-Montgomery Field) airport, and then choose from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you need to make your stay special. If you want an upscale hotel with a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Santee offers. During your visit, you might want to enjoy the restaurants and bars which Santee is known for.
When can I expect good weather in Santee?
Planning for the weather is an important factor for making your trip to Santee a success, especially when you're splurging. The hottest months are usually August and September with an average temp of 72°F, while the coldest months are February and January with an average of 56°F. Average annual precipitation for Santee is 13 inches.
What's there to see and do in Santee?
Enjoy Santee with a stop at Sportsplex USA Santee, Carlton Oaks Country Club, and Santee Lakes. If you have extra time while you're in the area, you might want to see Mission Trails Regional Park and Full Circle Saloon.
How can I get around Santee?
It's easier to get around town in style when you know your options. Head to Santee Town Center Station to catch metro.

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