Photo by Fabrice Récalt

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Go beyond your typical stay in Santana

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Check prices for these dates

Tonight
Nov 13 - Nov 14
Tomorrow
Nov 14 - Nov 15
This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

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Our top choices for Santana hotels

Front of property - evening/night

1. Roça Santo António Ecolodge Hotel

Roça Santo António Ecolodge Hotel
3.5 star property
Santana
8.4 out of 10, Very good, (16 reviews)
"Very friendly and helpful people. Great spot. It is out of the city so a good 'get away'. But you need your own vehicle."
United Kingdom
Anonymous traveler
The price is ￥22,082
￥39,526 total
includes taxes & fees
Nov 14 - Nov 15
Roça Santo António Ecolodge Hotel
A clear blue pool with a view of the ocean and a palm tree.

2. Pestana São Tomé

Pestana São Tomé
5.0 star property
Vila Maria
8.2 out of 10, Very good, (84 reviews)
"Wonderful stay, great staff, easy, relaxing delightful."
Canada
alexander
The price is ￥33,251
￥38,239 total
includes taxes & fees
Nov 14 - Nov 15
Pestana São Tomé
A pool with clear water reflecting palm trees and a building with outdoor seating.

3. Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection
4.0 star property
São Tomé
9.4 out of 10, Exceptional, (69 reviews)
"Lovely hotel, staff and location. Very close to airport as well Recommend highly"
United Kingdom
Kysha
The price is ￥28,596
￥33,806 total
includes taxes & fees
Nov 14 - Nov 15
Omali São Tomé – Principe Collection
A swimming pool with a gazebo, palm trees, and a building in the background.

4. Hotel Praia

Hotel Praia
3.5 star property
São Tomé
7.4 out of 10, Good, (18 reviews)
"Solid, basic hotel. "
United States
Jonathan
The price is ￥25,789
￥29,736 total
includes taxes & fees
Dec 14 - Dec 15
Hotel Praia
A beach view with palm trees, a small structure, and a road leading to the beach.

5. Emoyeni Gardens Hotel

Emoyeni Gardens Hotel
3.0 star property
Vila Maria
10.0 out of 10, Exceptional, (2 reviews)
"Great hospitality. Manager is incredibly friendly and staff was extremely professional. Very clean environment"
Canada
Leandro
The price is ￥21,106
￥24,272 total
includes taxes & fees
Nov 15 - Nov 16
Emoyeni Gardens Hotel
A cafe with orange chairs and tables, a counter with a display case, and a TV mounted on the wall.

6. Hotel Central

Hotel Central
3.5 star property
São Tomé
8.0 out of 10, Very good, (29 reviews)
"Hotel was good. Walking distance from everything in the city. The staff is helpful. The Wi-Fi is OK but for the money and cleanliness this is the best option in the city."
United States
Adam
The price is ￥7,215
￥8,488 total
includes taxes & fees
Nov 30 - Dec 1
Hotel Central
A building with a sign reading "Rosa porcelana" and another sign above it that says "Porcelana de Oregan LOA".

7. Porcelana Hotel

Porcelana Hotel
3.0 star property
Vila Maria
9.2 out of 10, Wonderful, (13 reviews)
"Great value for price. Nice staff. Excellent breakfast."
United States
Bonnie
The price is ￥4,838
￥5,564 total
includes taxes & fees
Dec 2 - Dec 3
Porcelana Hotel
A modern living room with a large window, a sofa, a coffee table, and a TV.

8. Hotel Kenito

Hotel Kenito
2.5 star property
São Tomé
10.0 out of 10, Exceptional, (5 reviews)
"The location of this property is great! The staff is accommodating and very friendly even if most don't speak English. The pool is amazing! breakfast is basic and the rooms are clean."
United States
Ada
The price is ￥12,304
￥14,150 total
includes taxes & fees
Nov 15 - Nov 16
Hotel Kenito
A swimming pool with a wooden deck and a gazebo, surrounded by palm trees and a clear sky.

9. Praia Accommodation

Praia Accommodation
3.0 star property
São Tomé
7.4 out of 10, Good, (19 reviews)
"Great place to stay "
United States
Daniel
The price is ￥17,451
￥20,069 total
includes taxes & fees
Dec 3 - Dec 4
Praia Accommodation
A dining table set with white plates, glasses, and cutlery, surrounded by wooden chairs.

10. Residencial Aeroporto

Residencial Aeroporto
3.0 star property
São Tomé
10.0 out of 10, Exceptional, (1 review)
"Prijs, ligging, comfort; erg goed. Eén ding zou echt opgelost moeten worden: de niet goed sluitende en heel erg krakende toiletdeur; de scharnieren moeten met een oliespuitje behandeld worden."
Netherlands
Willem
The price is ￥8,939
￥10,396 total
includes taxes & fees
Nov 14 - Nov 15
Residencial Aeroporto
Exterior detail

11. Hotel Vitória

Hotel Vitória
3.0 star property
São Tomé
7.6 out of 10, Good, (5 reviews)
"Tv channel was terrible, breakfast service not good enough, most times was problem with water, electricity and wify, the staff were friendly"
United Kingdom
Anonymous traveler
The price is ￥9,217
￥10,600 total
includes taxes & fees
Dec 6 - Dec 7
Hotel Vitória
A hotel with a swimming pool, palm trees, and a clear sky.

12. Miramar São Tomé

Miramar São Tomé
3.0 star property
São Tomé
7.2 out of 10, Good, (46 reviews)
"Very helpful and accommodating staff"
United States
sandra
The price is ￥24,149
￥27,772 total
includes taxes & fees
Nov 24 - Nov 25
Miramar São Tomé
A wooden house with a staircase leading to a balcony, surrounded by trees.

13. Guest House Quinta Natural

Guest House Quinta Natural
3.0 star property
Trindade
10.0 out of 10, Exceptional, (1 review)
The price is ￥4,831
￥8,118 total
includes taxes & fees
Nov 14 - Nov 15
Guest House Quinta Natural
A wooden covered porch with a railing, potted plants, and outdoor furniture.

14. Welfare Agroturismo

Welfare Agroturismo
3.0 star property
Trindade
The price is ￥9,988
￥11,751 total
includes taxes & fees
Dec 9 - Dec 10
Welfare Agroturismo
A lush garden with a variety of trees and plants, including a prominent red-leafed plant.

15. Casa de Ferias

Casa de Ferias
3.0 star property
São Tomé
9.0 out of 10, Wonderful, (7 reviews)
"I had a very good time here, got a lot of service and information from the family and in fact almost felt like a family member."
Sweden
Lars Roland
The price is ￥2,587
￥10,783 total
includes taxes & fees
Dec 14 - Dec 15
Casa de Ferias
A reception area with a wooden slat wall, woven wall hangings, a sofa, a reception desk, and two hanging pendant lights.

16. Agua Leve

Agua Leve
3.0 star property
São Tomé
The price is ￥6,296
￥7,322 total
includes taxes & fees
Nov 15 - Nov 16
Agua Leve
A swimming pool with a blue and red mosaic tile border, surrounded by palm trees and orange buildings.

17. Refúgio da Ilha

Refúgio da Ilha
3.0 star property
Conde
The price is ￥7,402
￥8,547 total
includes taxes & fees
Nov 14 - Nov 15
Refúgio da Ilha
A wooden deck with a table and two chairs, overlooking a scenic view of the ocean and lush greenery.

18. Mucumbli Hotel

Mucumbli Hotel
3.0 star property
Neves
9.6 out of 10, Exceptional, (29 reviews)
"A bit rustier than i expected. Beds were SUPER sq "
Norway
Morten
The price is ￥21,116
￥24,348 total
includes taxes & fees
Dec 1 - Dec 2
Mucumbli Hotel
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees.

19. Roulotte Beach São Tomé

Roulotte Beach São Tomé
3.0 star property
Conde
The price is ￥14,615
￥16,972 total
includes taxes & fees
Dec 11 - Dec 12
Roulotte Beach São Tomé
A modern living room with a black sofa, a round coffee table, and a dining area with a white table and black chairs.

20. Nour Apartments

Nour Apartments
2.5 star property
São Tomé
The price is ￥8,294
￥9,538 total
includes taxes & fees
Dec 13 - Dec 14
Nour Apartments
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santana

Venture to São Sebastião Museum and São Nicolau Waterfall—just two of the sights around Santana.

See all hotels in Santana
A coastal landscape with a wooden deck, lush green foliage, and a view of the ocean under a cloudy sky.
Photo by Fabrice Récalt
Open Photo by Fabrice Récalt

Top Santana Hotel Reviews

A building with a sign reading "Rosa porcelana" and another sign above it that says "Porcelana de Oregan LOA".
Porcelana Hotel

Porcelana Hotel

Porcelana Hotel
Vila Maria

10/10 Excellent

Great value for price. Nice staff. Excellent breakfast.
United States
Bonnie
Reviewed February 22, 2026
Porcelana Hotel

Frequently Asked Questions

What are some of the best vacation rentals that Santana has to offer?

Alojamento Santos Silva : This vacation home rental outside of Santana offers an outdoor pool, a garden, and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include an oven, a microwave, and kitchenware. See all vacation rentals in Santana.

If I need to cancel my hotel reservation in Santana, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santana.

Where can I learn more about changing or cancelling my trip to Santana?

To access more information about updating your trip to Santana or cancelling it, go to https://www.expedia.com/service/.

What's the best hotel for families in Santana?

Roça Santo António Ecolodge Hotel is a hotel with a children's pool and a restaurant, and it's a top choice on Expedia for families. Attractions in the area like Cloçon Téla Chocolate Factory are also fun for the whole family. Find more child-friendly accommodations in Santana.

What are some accommodations with pools in Santana?

Roça Santo António Ecolodge Hotel is a top hotel with a children's pool, an outdoor pool, and free buffet breakfast. View all hotels with pools in Santana.