Find hotels in Barrio de Guadalupe, San Cristóbal de las Casas

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 21 - Dec 22
Tomorrow
Dec 22 - Dec 23
Next weekend
Dec 26 - Dec 28
In two weeks
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Barrio de Guadalupe hotels

Superior Villa | Living area | Fireplace
Jungla Hotel Boutique

Jungla Hotel Boutique

Jungla Hotel Boutique
2.0 star property
Barrio de Guadalupe
10.0 out of 10, Exceptional, (2)
"Todo"
Mexico
Rodolfo antonio
The price is ￥10,494
￥12,383 total
includes taxes & fees
Dec 22 - Dec 23
Jungla Hotel Boutique
Garden
Casavieja

Casavieja

Casavieja
4.0 star property
Barrio de Guadalupe
8.8 out of 10, Excellent, (332)
"Good location and nice staff "
Canada
Max
Casavieja
Outdoor dining
Hotel Parador Margarita

Hotel Parador Margarita

Hotel Parador Margarita
3.5 star property
Barrio de Guadalupe
9.0 out of 10, Wonderful, (145)
"One of the best places I’ve stayed in San Cristobal — old and charming building, but comfortable rooms with modern amenities. Friendly staff, lovely area — central but not noisy."
Canada
Jessica
The price is ￥7,870
￥9,287 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Parador Margarita
Property entrance
Taller de Juan - Casa Hotel

Taller de Juan - Casa Hotel

Taller de Juan - Casa Hotel
3.5 star property
Barrio de Guadalupe
9.6 out of 10, Exceptional, (64)
"We loved the staff and the attention to detail. "
United States
Refugio
Taller de Juan - Casa Hotel
Interior detail
Hotel Ocho Barrios

Hotel Ocho Barrios

Hotel Ocho Barrios
3.0 star property
Barrio de Guadalupe
9.2 out of 10, Wonderful, (32)
"The location was excellent.My room was spacious and comfortable, staff very friendly and breakfast was delicious"
United States
Eduardo
The price is ￥7,481
￥9,408 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Ocho Barrios
Interior
Tierra Alta Hostal

Tierra Alta Hostal

Tierra Alta Hostal
3.0 star property
Barrio de Guadalupe
9.6 out of 10, Exceptional, (13)
"I stayed here last week and loved it so much I came back. Everything about this place is exceptional. This will be my to-go place to stay while in San Cris. "
United States
Damaris
Tierra Alta Hostal
32-inch flat-screen TV with satellite channels, TV
Yox Hotel Boutique

Yox Hotel Boutique

Yox Hotel Boutique
2.5 star property
Barrio de Guadalupe
9.2 out of 10, Wonderful, (97)
"Location is perfect everything close to the hotel "
United States
Jose
The price is ￥7,397
￥8,729 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Yox Hotel Boutique
Double Room, 2 Queen Beds | Iron/ironing board, free WiFi, bed sheets
Hotel Cielo y Selva, San Cristobal de las Casas

Hotel Cielo y Selva, San Cristobal de las Casas

Hotel Cielo y Selva, San Cristobal de las Casas
3.0 star property
Barrio de Guadalupe
8.6 out of 10, Excellent, (112)
"The staff was very friendly and helpful all the time!"
United States
MAYRA
The price is ￥6,598
￥7,786 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Cielo y Selva, San Cristobal de las Casas
Basic Triple Room | Free WiFi
Yagil B&B

Yagil B&B

Yagil B&B
2.0 star property
Barrio de Guadalupe
The price is ￥5,903
￥6,965 total
includes taxes & fees
Dec 22 - Dec 23
Yagil B&B
Living area
Hotel Tepeyac

Hotel Tepeyac

Hotel Tepeyac
3.0 star property
Barrio de Guadalupe
9.0 out of 10, Wonderful, (132)
"Great location, although need to be mindful of the noise at night due to parties and nightlife. The property was very beautiful, tidy and staff were super friendly. "
Canada
Raul
Hotel Tepeyac
Rooftop terrace
Hotel Jovel

Hotel Jovel

Hotel Jovel
3.0 star property
Barrio de Guadalupe
8.0 out of 10, Very Good, (107)
"NO ME AGRADO QUE EL ESTACIONAMIENTO ESTÁ A DOS CIADRAS Y EL HORARIO ES LIMITADO."
Mexico
ALEJANDRO
The price is ￥5,159
￥6,088 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Hotel Jovel
Standard Quadruple Room | Premium bedding, down comforters, desk, free WiFi
Hotel Casa del Sol

Hotel Casa del Sol

Hotel Casa del Sol
2.5 star property
Barrio de Guadalupe
8.8 out of 10, Excellent, (6)
"Friendly good but need to change more details "
United States
wook
The price is ￥6,559
￥7,740 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel Casa del Sol
Terrace/patio
Guayaba Inn Boutique Hotel

Guayaba Inn Boutique Hotel

Guayaba Inn Boutique Hotel
4.0 star property
Barrio del Cerrillo, 0.4 km from Barrio de Guadalupe
9.8 out of 10, Exceptional, (259)
"T"
Mexico
Francisco
The price is ￥16,527
￥19,502 total
includes taxes & fees
Dec 22 - Dec 23
Guayaba Inn Boutique Hotel
Property amenity
Hotel Sombra del Agua

Hotel Sombra del Agua

Hotel Sombra del Agua
3.5 star property
Zona Centro, 1 km from Barrio de Guadalupe
9.4 out of 10, Exceptional, (1003)
"Fantastic location & beautiful colonial building."
United Kingdom
Julia
The price is ￥14,267
￥16,835 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Hotel Sombra del Agua
Daily cooked-to-order breakfast for a fee
Hotel Ciudad Real Centro Histórico

Hotel Ciudad Real Centro Histórico

Hotel Ciudad Real Centro Histórico
3.5 star property
Zona Centro, 1 km from Barrio de Guadalupe
8.8 out of 10, Excellent, (488)
"Wonderful hotel. Staff was great and the rooms were clean in a great location, right across the street from the main park and zocalo. The only issue was that the Internet was spotty at times and would be unavailable for short periods which is typical with hotels in older building. "
United States
Rocio
The price is ￥11,672
￥13,773 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Ciudad Real Centro Histórico
Aerial view
Hotel Bo

Hotel Bo

Hotel Bo
4.0 star property
Barrio de Mexicanos, 1.2 km from Barrio de Guadalupe
9.8 out of 10, Exceptional, (287)
"Excelente hotel"
Mexico
Claudia
The price is ￥56,290
￥66,422 total
includes taxes & fees
Dec 22 - Dec 23
Hotel Bo
Restaurant
Hotel Junvay

Hotel Junvay

Hotel Junvay
3.0 star property
Barrio de Mexicanos, 1.1 km from Barrio de Guadalupe
9.4 out of 10, Exceptional, (85)
"I loved this hotel! The staff were incredibly warm and kind. I had two rooms - both overlooked the courtyard and were beautiful. Exposed beams, great pillows, delicious breakfast, and perfect location. "
United States
Jennifer
Hotel Junvay
Exterior detail
HOTEL PLAZA 79

HOTEL PLAZA 79

HOTEL PLAZA 79
3.5 star property
Santa Lucía, 0.3 km from Barrio de Guadalupe
9.4 out of 10, Exceptional, (90)
"The hotel was exceptional and the staff were always welcoming and respectful. Definitely recommend this hotel to anyone traveling to San Cristobal de las Casas! "
United States
Victor Ernesto
The price is ￥22,918
￥27,043 total
includes taxes & fees
Jan 5 - Jan 6, 2026
HOTEL PLAZA 79
Courtyard
Hotel Na Bolom

Hotel Na Bolom

Hotel Na Bolom
3.0 star property
Barrio del Cerrillo, 0.4 km from Barrio de Guadalupe
9.0 out of 10, Wonderful, (67)
"Clean, quiet, comfortable. I’ll stay at this hotel again! "
United States
JAMES
The price is ￥5,669
￥6,690 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Na Bolom
Queen Room | In-room safe, individually decorated, individually furnished, desk
Casa Santa Lucía

Casa Santa Lucía

Casa Santa Lucía
3.5 star property
Zona Centro, 0.7 km from Barrio de Guadalupe
10.0 out of 10, Exceptional, (161)
"Nice hotel!, very close to the zocalo"
United States
Pedro
The price is ￥15,740
￥18,573 total
includes taxes & fees
Dec 22 - Dec 23
Casa Santa Lucía
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Barrio de Guadalupe

Find the best Barrio de Guadalupe areas and neighborhoods for the activities you enjoy most.
San Cristobal de las Casas which includes heritage elements

Zona Centro

Unique features of Zona Centro include the museums and gardens. Make a stop by Mesoamerican Museum of Jade or Foro Cultural Kinoki while you're exploring the area.

Arches of Carmen featuring heritage elements and cycling as well as an individual male

Santa Lucía

While visiting Santa Lucía, you might make a stop by sights like Santo Domingo Handicraft Market and Arches of Carmen.

Barrio de La Merced

While visiting Barrio de La Merced, you might make a stop by sights like Amber Museum of Chiapas and Regional Costume Museum.

San Cristobal de las Casas featuring interior views

Barrio del Cerrillo

If you're spending some time in Barrio del Cerrillo, Na Bolom Cultural Museum and Ex-Convent of Santo Domingo are top sights worth seeing.

De Cuxtitali

When in De Cuxtitali, you can plan a visit to Na Bolom Cultural Museum and Ex-Convent of Santo Domingo, some noteworthy sights in the nearby area.

Top Barrio de Guadalupe Hotel Reviews

Hotel Hacienda Don Juan

Hotel Hacienda Don Juan

10/10 Excellent
"Clean Beautiful Great service Great breakfast "
Patrick 5-night trip
Posted 10 days ago
Hotel Hacienda Don Juan

Frequently asked questions

What is Barrio de Guadalupe like?
You'll be sure to have fun visiting San Cristóbal de las Casas's Barrio de Guadalupe neighborhood.
What's a favorite hotel to stay in Barrio de Guadalupe?
Based on Expedia customer reviews, Taller de Juan - Casa Hotel is the highest ranked property in Barrio de Guadalupe. This hotel is a short 8-minute walk from San Cristóbal de las Casas Cathedral, and it offers a restaurant and a bar. Other favorite options in the area include Hotel Ocho Barrios and Hotel Cielo y Selva, San Cristobal de las Casas.
How many hotels are there in the Barrio de Guadalupe area?
Expedia has 61 hotels and other accommodations in Barrio de Guadalupe to choose from, making this an ideal home base for exploring the greater San Cristóbal de las Casas area.
If I need to cancel my hotel reservation in Barrio de Guadalupe, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Barrio de Guadalupe.
Where can I learn more about changing or cancelling my trip to Barrio de Guadalupe?
To find more details about updating your trip to Barrio de Guadalupe or cancelling it, click here.
What is there to do in this San Cristóbal de las Casas neighborhood?
A few places to visit in the area around Barrio de Guadalupe include Na Bolom Cultural Museum, Galeria Studio Cerrillo, and Foro Cultural Kinoki. Café Museo Café and Church of San Nicolás are also worth a visit when you're out sightseeing in San Cristóbal de las Casas.