Find Family Hotels in Picayune, MS

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Check availability on Picayune Family Hotels

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Picayune family-friendly hotels

Exterior
Holiday Inn Express Picayune-Stennis Space Center by IHG

Holiday Inn Express Picayune-Stennis Space Center by IHG

Holiday Inn Express Picayune-Stennis Space Center by IHG
2.5 star property
Picayune
9.0 out of 10, Wonderful, (644)
"Clean room and facility."
United States
Joshua
The price is ￥16,062
￥17,508 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Holiday Inn Express Picayune-Stennis Space Center by IHG
Terrace/patio
Adorable 3 bedroom attached cottage in quiet spot.

Adorable 3 bedroom attached cottage in quiet spot.

Adorable 3 bedroom attached cottage in quiet spot.
Picayune
10.0 out of 10, Exceptional, (38)
"This property was very clean and quiet. Very cute little place to stay. I would 100% stay again."
United States
Melinda M.
The price is ￥14,736
￥24,562 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Adorable 3 bedroom attached cottage in quiet spot.
In-room safe, desk, iron/ironing board, free WiFi
Super 8 by Wyndham Picayune

Super 8 by Wyndham Picayune

Super 8 by Wyndham Picayune
2.0 star property
Picayune
6.4 out of 10, (230)
"Dirty ,, had a big roach crawling on me while sleeping, no phone in the room, no wifi "
United States
Perla
The price is ￥7,300
￥7,957 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Super 8 by Wyndham Picayune
Interior
The Henry Smith House-Annex.

The Henry Smith House-Annex.

The Henry Smith House-Annex.
2.0 star property
Picayune
9.6 out of 10, Exceptional, (7)
"Lovely home; great ameneties"
United States
veronica
The price is ￥42,104
￥69,579 total
includes taxes & fees
Jan 8 - Jan 9, 2026
The Henry Smith House-Annex.
Pool
Econo Lodge Picayune

Econo Lodge Picayune

Econo Lodge Picayune
2.0 star property
Picayune
6.2 out of 10, (135)
"The staff was friendly and it was very quiet. The pool was not open and the room could really use updating."
United States
Heather
The price is ￥11,367
￥12,390 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Econo Lodge Picayune
Exterior
Quality Inn Slidell I-10

Quality Inn Slidell I-10

Quality Inn Slidell I-10
2.5 star property
Slidell
7.6 out of 10, Good, (281)
"Good staff nice rooms for the price "
United States
Matt
The price is ￥9,146
￥10,705 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Quality Inn Slidell I-10
Lobby
Ramada by Wyndham Diamondhead I-10/Gulfport

Ramada by Wyndham Diamondhead I-10/Gulfport

Ramada by Wyndham Diamondhead I-10/Gulfport
2.5 star property
Diamondhead
8.0 out of 10, Very Good, (570)
"This place was like a diamond in the rough. It looks older but the rooms are nice and clean. The beds are very comfortable also. We enjoyed our stay"
United States
bobby
The price is ￥10,305
￥11,232 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Ramada by Wyndham Diamondhead I-10/Gulfport
Front of property - evening/night
Baymont by Wyndham Slidell

Baymont by Wyndham Slidell

Baymont by Wyndham Slidell
2.5 star property
Slidell
8.2 out of 10, Very Good, (650)
"Rooms were good, staff was friendly "
United States
Carol
The price is ￥11,789
￥13,662 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Baymont by Wyndham Slidell
Front of property
Comfort Inn & Suites Slidell - New Orleans Area

Comfort Inn & Suites Slidell - New Orleans Area

Comfort Inn & Suites Slidell - New Orleans Area
3.0 star property
Slidell
8.6 out of 10, Excellent, (1002)
"The rooms were clean and well kept"
United States
Navin
The price is ￥15,257
￥17,649 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Comfort Inn & Suites Slidell - New Orleans Area
Outdoor pool
Best Western Slidell Hotel

Best Western Slidell Hotel

Best Western Slidell Hotel
2.5 star property
Slidell
8.2 out of 10, Very Good, (1000)
"The stay was great"
United States
Joseph
The price is ￥13,193
￥15,304 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Best Western Slidell Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Picayune Hotel Reviews

Motel 6 Slidell, LA - New Orleans

Motel 6 Slidell, LA - New Orleans

10/10 Excellent
"Nice stay. Room was spacious and clean. Room had microwave and fridge. Employees were very friendly. Have a good time over all. "
Debbie 1-night trip
Posted 20 hours ago
Motel 6 Slidell, LA - New Orleans

Frequently asked questions

What's Picayune like for family-friendly vacations?
The budget-friendly destination of Picayune is a good choice if you've been considering a getaway with your kids. The excursions, swimming spots, and golfing are just some of the things that make this the perfect spot for family trips. Fly into Gulfport - Biloxi Intl. Airport (GPT), which is located 37 mi (59.5 km) from the city center.
What's the best accommodation when traveling with kids to Picayune?
Holiday Inn Express Picayune-Stennis Space Center by IHG is a hotel with an indoor pool and free parking, and it's a top choice on Expedia for families.
When's the best time to book a family-friendly vacation in Picayune?
The hottest months are usually August and July with an average temp of 80°F, while the coldest months are January and December with an average of 55°F. The rainiest months in Picayune are August, July, June, and May, with each month seeing an average of 8 inches of rainfall.
What's there to see and do with your family in Picayune?
While you and your family are staying in Picayune, you might want to visit some family-friendly attractions such as M. M. Roberts Stadium, Crosby Memorial Library, and Teddy Bear Museum. Make sure you have lots of time for activities like Carver Museum and NASA Stennis Space Center.
What's the best way for us to get around Picayune?
If you want to explore the larger area, hop on a train at Picayune Station. Picayune may not have many public transit options so consider renting a car to explore more.