Otay Mesa West Vacations from ￥286,732

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The Latest Otay Mesa West Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Catamaran Resort and Spa

Catamaran Resort and Spa

4 out of 5
Mission Beach
per person
Sep 13 - Sep 19
found 9 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Diego (SAN)
8.2/10 Very Good! (1,007 reviews)
Room fridge didn't work. Super noisy balcony door, when room above opened or closed it, it sounded like heavy machinery ruining on top of your room. Funy smell on the 11th tower floor

Reviewed on Jun 28, 2025

Barsala City Villas

Barsala City Villas

2.5 out of 5
Downtown San Diego
Save 100% on your flight
per person
Sep 13 - Sep 19
found 9 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Diego (SAN)
No reviews
Walk to Dining, Mission + Pacific Beach, and Bars/nightlife Private Backyard

Walk to Dining, Mission + Pacific Beach, and Bars/nightlife Private Backyard

3 out of 5
Pacific Beach
per person
Sep 13 - Sep 19
found 9 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Diego (SAN)
No reviews
The Wayfarer San Diego

The Wayfarer San Diego

4 out of 5
Mission Beach
per person
Sep 13 - Sep 19
found 9 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Diego (SAN)
9.2/10 Wonderful! (1,486 reviews)
We had an enjoyable stay. The bistro in the main lobby in a nice addition.

Reviewed on Jun 29, 2025

Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
per person
Sep 13 - Sep 19
found 9 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to San Diego (SAN)
8.6/10 Excellent! (2,172 reviews)
Felt like a small, safe community.

Reviewed on Jun 29, 2025

Where to stay in Otay Mesa West

Find the best Otay Mesa West areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa West
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Find hotels in Downtown San Diego

Otay Mesa West Hotel Deals

Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is ￥22,008 per night from Jul 2 to Jul 3
￥22,008
￥29,712 total
Jul 2 - Jul 3
includes taxes & fees
8.2/10 Very Good! (5,713 reviews)
"Great location, parking is expensive but overall nice place"

Reviewed on Jun 28, 2025

Wyndham San Diego Bayside
Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina
4 out of 5
333 W Harbor Dr, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is ￥35,584 per night from Jul 6 to Jul 7
￥35,584
￥47,828 total
Jul 6 - Jul 7
includes taxes & fees
9/10 Wonderful! (1,729 reviews)
"Parking rate seemed exorbitant. Bed was too firm."

Reviewed on Jun 28, 2025

Marriott Marquis San Diego Marina
Handlery Hotel
Handlery Hotel
3.5 out of 5
950 Hotel Cir N, San Diego, CA
Fully refundableReserve now, pay when you stay
The price is ￥14,741 per night from Jul 2 to Jul 3
￥14,741
￥16,944 total
Jul 2 - Jul 3
includes taxes & fees
8/10 Very Good! (1,832 reviews)
"👍"

Reviewed on Jun 28, 2025

Handlery Hotel
See all 6,561 properties in Otay Mesa West
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Otay Mesa West vacation package cost?
Discover the best of Otay Mesa West from as little as ￥286,732. Choose from a wonderful selection of flights, hotels and rental cars to suit every style and budget. You can score even better deals when you add some experiences or tours to your package.
How do I get a cheap travel package to Otay Mesa West?
Booking an Otay Mesa West vacation package with Expedia is the easiest way to save. We have over 550 partner airlines and 1,000,000 properties across the globe. With such an awesome range to select from, you'll have no trouble putting together your next dream vacation.
Where should I stay in Otay Mesa West?
You'll want to stay where the action is. Many people book hotels around popular attractions, like Las Americas Premium Outlets, North Island Credit Union Amphitheatre and Aquatica.
How far in advance should I book my Otay Mesa West vacation?
Smart travelers will likely want to book early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you're booking last minute, don't despair. Low prices sometimes appear just weeks before departure dates.
What does an Expedia Otay Mesa West travel package include?
It all depends on what type of getaway you're contemplating. Otay Mesa West vacation deals can include hotels, car rentals and flights. You can mix and match to find the travel package that fits your needs. You can also add on experiences and activities after you've booked to score even bigger discounts.
What should I know before booking an Otay Mesa West travel package?
Get ready to save with an Expedia travel package. Bundle your airfares, rental cars and hotels and pick up fabulous discounts. You're not limited to hotels, though. Book with us and select from beach villas, mountain cabins and everything in between!
Can I choose my airline with an Otay Mesa West Expedia vacation package?
With a vacation package, you're the boss. Whether you'd like to fly to Otay Mesa West in economy or business class, simply pick from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Otay Mesa West vacation package?
You can. We get that even the best-laid plans can go awry, so we're here to help if you need to make changes to your Otay Mesa West vacation package. You may be able to cancel or change your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Head to our Customer Service Portal for further information. Also, be sure to check your itinerary for the nitty-gritty on change fees.

Discover the most popular places to visit in Otay Mesa West

San Diego Zoo featuring landscape views, zoo animals and a pond

San Diego Zoo

4.5/5(3,565 reviews)

See nature up-close and personal at one of the country’s largest and most educational zoos.

San Diego Zoo
Mission Bay featuring a sandy beach

Mission Bay

4.5/5(2,386 reviews)

Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.

Mission Bay
San Diego Convention Center

San Diego Convention Center

4.5/5(1,297 reviews)

During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's fascinating museums and acclaimed art scene.

San Diego Convention Center

Things to do

San Diego City Lights Night Tour

San Diego City Lights Night Tour

￥5,654
per adult
96% of travellers recommend
San Diego City Lights Night Tour
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

￥17,930
per adult
86% of travellers recommend
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
San Diego Whale Watching Tour

San Diego Whale Watching Tour

￥10,267
per adult
86% of travellers recommend
San Diego Whale Watching Tour
See all activities in San Diego
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.