The Best Hotels Closest to Lester E. Cox Medical Center South in Springfield for 2026

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Our top choices for Lester E. Cox Medical Center South hotels

A conference room with a granite table, cushioned chairs, a fruit bowl, framed pictures, and a flat-screen TV.

A living room with patterned armchairs, a dark sofa, a glass coffee table, and framed artwork on the walls.

A gym with various exercise machines, a clock, and a motivational sign.

The exterior of Hampton Inn with a clear sign, a welcome sign, and a clearance height sign.

1. Hampton Inn Springfield-South

Galloway Village, 2 km from Lester E. Cox Medical Center South

Bradford

￥15,889

￥18,035 total

includes taxes & fees

Sep 13 - Sep 14

An outdoor patio area with red seating, a fire feature, and tables and chairs.

A modern hotel with a dark facade, multiple windows, and an American flag.

A modern living room with a sectional sofa, a coffee table, and yellow armchairs. There is a dining area with a table and chairs in the background.

A modern hotel lobby with a bar, seating area, kitchen, and a TV.

2. Homewood Suites by Hilton Springfield Medical District

1.4 km from Lester E. Cox Medical Center South

Heather

￥21,655

￥24,580 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with a blue sofa, two single beds, a nightstand, a lamp, and a framed picture on the wall.

A living room with a blue sofa, a small round table, a patterned carpet, and a kitchenette area.

A Holiday Inn Express & Suites hotel with a parking lot, a covered entrance, and a view of the surrounding area.

A coffee station with two coffee machines and a variety of coffee pods and cups.

3. Holiday Inn Express and Suites Springfield Medical District by IHG

1.6 km from Lester E. Cox Medical Center South

Gwen

￥20,939

￥23,767 total

includes taxes & fees

Oct 4 - Oct 5

A hotel room with two beds, a desk, a chair, a TV, and a bathroom with a sink and mirror.

A spacious lobby with a pool, comfortable seating, and a reception desk.

A multi-story hotel with a prominent "Candlewood Suites" sign, a parking lot, and a landscaped entrance area.

A modern kitchen with a stainless steel microwave, a coffee maker, and a refrigerator.

4. Candlewood Suites Springfield-Medical District

0.9 km from Lester E. Cox Medical Center South

Richard

￥18,439

￥20,931 total

includes taxes & fees

Sep 10 - Sep 11

An outdoor patio area with wicker furniture, a central fire pit, and large windows.

A lobby with a fireplace, large windows, and a view of the outdoors.

An indoor swimming pool with clear water, surrounded by a tiled floor and a glass wall.

A spacious hotel lobby with high ceilings, large windows, and a central seating area with tables and chairs.

5. Hilton Garden Inn Springfield, MO

Lake Springfield, 2.7 km from Lester E. Cox Medical Center South

Abel

￥17,811

￥20,404 total

includes taxes & fees

Sep 12 - Sep 13

A spacious lounge area with comfortable seating, a fireplace, and artwork on the walls.

A hotel room with a desk, chair, TV, fireplace, bed, and a small dining area.

An outdoor patio with wicker furniture, a round table, and a grill area.

A modern kitchen with a central island, bar stools, a dining table, and a bar area.

6. Residence Inn by Marriott Springfield

0.8 km from Lester E. Cox Medical Center South

Darren

￥18,462

￥20,955 total

includes taxes & fees

Oct 4 - Oct 5

A spacious living area with large windows, a bar, and modern furniture.

A modern kitchen with a bar area, featuring a large TV, wooden shelves, and bar stools.

A spacious kitchen with a large island, ample seating, and a view of the cityscape through large windows.

A modern hotel building with a prominent 'element by Westin' sign, multiple floors, and a covered entrance area.

7. Element by Marriott Springfield South

Meador Park, 1.5 km from Lester E. Cox Medical Center South

ROSA MARIA LOPEZ

￥21,720

￥24,654 total

includes taxes & fees

Sep 7 - Sep 8

A hotel room with two beds, a desk with a computer, a TV, and a coffee maker.

A hotel dining area with multiple tables and chairs, a kitchen counter with coffee machines, and a wall-mounted clock.

A compact hotel room with a sofa, a small table, a TV, and a desk with a coffee machine.

An indoor swimming pool with a tiled floor, a pool ladder, and a glass door leading to another room.

8. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 2.8 km from Lester E. Cox Medical Center South

Edward

￥14,126

￥16,322 total

includes taxes & fees

Sep 27 - Sep 28

A modern living room with a flat-screen TV, a fireplace, a sofa, and a dining area with a kitchen counter.

A kitchen area with a coffee machine, a buffet setup, and a dining table with chairs.

A compact kitchen with a microwave, toaster, and refrigerator.

A modern living room with a fireplace, a sofa, a TV, and a staircase leading to a bedroom.

9. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.7 km from Lester E. Cox Medical Center South

Carla

￥14,477

￥16,433 total

includes taxes & fees

Oct 5 - Oct 6

An indoor swimming pool with a glass ceiling, surrounded by lounge chairs and a view of the outdoors.

A hotel room with a large bed, a wooden nightstand with a phone, two wall-mounted lamps, and a window with curtains.

A Comfort Inn hotel with a modern facade, a covered entrance, and a parking lot.

A modern living room with blue sofas, a stone accent wall, and a bookshelf.

10. Comfort Inn South - Springfield

Galloway Village, 2.3 km from Lester E. Cox Medical Center South

Roger

￥15,470

￥17,560 total

includes taxes & fees

Sep 27 - Sep 28

A modern hotel lobby with a leather sofa, green chairs, a black coffee table, and a kitchen area with a green countertop.

A swimming pool with a lifeguard tower, surrounded by a fence and seating area.

A spacious indoor dining area with multiple round tables and chairs, large windows, and a modern staircase.

A hotel room with two beds, a desk with a chair, a flat-screen TV, and a large window with curtains.

11. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.5 km from Lester E. Cox Medical Center South

Marlin Van

￥13,893

￥15,769 total

includes taxes & fees

Oct 4 - Oct 5

A hotel lobby with a reception desk, a staircase, and a seating area.

A kitchen with a wooden table and chairs, a coffee machine, a fruit juicer, and a refrigerator.

A swimming pool with a hot tub, tiled floor, and a few lounge chairs.

A modern hotel lobby with a sofa, armchairs, a coffee table, and a staircase.

12. Sleep Inn Springfield South I60 near Medical District

1.8 km from Lester E. Cox Medical Center South

Ping

￥13,187

￥14,968 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with a large bed, a chair, a nightstand, a lamp, and a door.

A hotel with a prominent sign for 'extended stay America' and a parking lot with several cars.

A hotel room with a brown leather sofa, a small table, a floor lamp, and a green accent wall.

A hotel reception area with a reception desk, a framed artwork, and an exit sign.

13. Extended Stay America Select Suites Springfield South

0.9 km from Lester E. Cox Medical Center South

Crystal

￥12,374

￥14,046 total

includes taxes & fees

Sep 7 - Sep 8

A hotel room with a bed, bedside table, lamp, and a painting of a sunset.

A modern dining area with blue chairs and white tables, a flat-screen TV mounted on the wall, and a wooden cabinet with items on it.

A lobby with a mural, seating area, and a refrigerator labeled 'NOURISH' and 'RECHARGE'.

A gym with exercise equipment, a treadmill, and a wall mural of athletes.

14. Clarion Pointe Springfield Southeast

Galloway Village, 4.8 km from Lester E. Cox Medical Center South

Stephen

￥13,429

￥15,244 total

includes taxes & fees

Sep 13 - Sep 14

A cozy living room with a stone fireplace, comfortable seating, and a large mirror reflecting the room.

An indoor swimming pool with a clear water line, surrounded by lounge chairs and tables.

A hotel with a clear entrance, a covered waiting area, and a parking lot.

A hotel lobby with a large bar area, seating, a fireplace, and framed pictures on the walls.

15. Hampton Inn Springfield-Southeast

Galloway Village, 4.9 km from Lester E. Cox Medical Center South

Kenneth

￥17,298

￥19,635 total

includes taxes & fees

Sep 13 - Sep 14

A hotel room with two beds, a wooden headboard, bedside tables with lamps, and a small nightstand.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

An outdoor seating area with wicker chairs and a fire feature.

A gym with treadmills, weight machines, and exercise mats.

16. Holiday Inn Express & Suites Springfield North by IHG

11.8 km from Lester E. Cox Medical Center South

Jerry

￥16,407

￥18,624 total

includes taxes & fees

Sep 13 - Sep 14

A modern hotel room with a kitchenette, a flat-screen TV, a bed, and a large window.

A modern hotel room with a dark grey sofa, a wooden side table, a desk with a chair, and two abstract paintings on the walls.

A hotel reception area with a modern design, including a reception desk, a wall with geometric patterns, and a minibar.

A modern kitchen with wooden cabinets, a countertop with various kitchen items, and a wall-mounted shelf with decorative objects.

17. SpringHill Suites by Marriott Springfield North

Parkwood, 11.6 km from Lester E. Cox Medical Center South

Katie

￥17,134

￥20,151 total

includes taxes & fees

Sep 13 - Sep 14

An outdoor patio with stone walls, round tables, chairs, and umbrellas.

A modern hotel room with a stone accent wall, a flat-screen TV, a fireplace, a sofa, a dining area, and a patterned carpet.

An indoor swimming pool with clear glass walls, lounge chairs, and a lifeguard chair.

A Fairfield Inn & Suites Marriott hotel with a modern design, featuring a prominent entrance and a parking lot.

18. Fairfield Inn & Suites by Marriott Springfield North

Doling, 10.7 km from Lester E. Cox Medical Center South

Mariya

￥17,053

￥19,752 total

includes taxes & fees

Sep 13 - Sep 14

A spacious living area with a large island table, comfortable seating, and a view of an outdoor patio.

A modern living area with a stone accent wall, a wooden herringbone pattern wall, a flat-screen TV, and a seating area with sofas and chairs.

A spacious living area with large windows, modern furniture, and a view of a building and pool outside.

A lobby with stone walls, leather sofas, a Christmas tree, and a dining area.

19. Best Western Courtview Hotel

Galloway Village, 5 km from Lester E. Cox Medical Center South

Millicent

￥13,806

￥15,671 total

includes taxes & fees

Sep 13 - Sep 14

A spacious indoor dining area with multiple tables and chairs, a kitchen area, and large windows allowing natural light.

A modern lobby with a reception desk, seating area, and a high ceiling with recessed lighting.

A spa area with a hot tub, a pool, and a seating area with tables and chairs.

A Drury Inn & Suites hotel with a modern design, featuring a prominent entrance and stone pillars.

20. Drury Inn & Suites Springfield, MO

11.2 km from Lester E. Cox Medical Center South

Gregory

￥16,562

￥18,966 total

includes taxes & fees

Sep 13 - Sep 14

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Star rating	Guest rating
Hampton Inn Springfield-South	9.4 Exceptional 705 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 Exceptional 550 reviews	View
Holiday Inn Express and Suites Springfield Medical District by IHG	9.4 Exceptional 1,001 reviews	View
Candlewood Suites Springfield-Medical District	9.2 Wonderful 433 reviews	View
Hilton Garden Inn Springfield, MO	9.0 Wonderful 870 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

Homewood Suites by Hilton Springfield Medical District

10/10 Excellent

"Shout out to the front desk staff! super helpful!"

Comfort Inn South - Springfield

10/10 Excellent

"Room was clean and had plenty of towels. There was a refrigerator and microwave. Saw that they recycled! Breakfast was okay. The second morning we went to IHOP which is next door. Pool and hot tub was nice."

Peaceful Retreat near Medical Mile in Springfield

10/10 Excellent

"Very pleased with this house and with our stay. Everything was nicer than our expectation. And nicer than it looks in the pictures. (pictures look great, but it is even nicer.!!)Lots of small touches . There’s a couple shelves of books with a wide variety and options for small children through adults. There are some games and toys for kids to play and games. The whole family can play. The kitchen has many extras, like coffee and coffee pods, a few basic spices, plenty of dishes, including dishes for kids, pans, mixing & serving bowls… it’s all here.The host was easy to work with and very communicative. The home is well lit, and we felt very comfortable in the neighborhood. We are back in Springfield again, this is definitely the place we’ll be looking for.!! thank you to our hosts"

Holiday Inn Express and Suites Springfield Medical District by IHG

10/10 Excellent

"Pleasantly satisfied with this hotel."

Cozy Central Home by CoxHealth & MSU - Fenced Yard

10/10 Excellent

"As advertised. Clean and good neighborhood."

Sleep Inn Springfield South I60 near Medical District

8/10 Good

"The hotel and staff were top of the game. The only complaint that we had due our stay was that the breakfast was never stocked. The person working it acted like they wanted to not put much out so it was easy to clean at the end. If there was 1 muffin avail, they would wait til someone took that muffin and then put one more out. Once the gravy ran out they did not make any more. Could go on and on but you get the picture."

Comfortable Home Near CoxHealth & MSU - Fenced Yard

10/10 Excellent

"Spacious house and very well maintained. Host was very responsive on answering our questions. We do an annual family reunion and this worked very well for us. Would definitely stay here again while in the area."

Elevate Your Stay in Our Stunning Loft with 17-Foot Ceilings

10/10 Excellent

"Unique stay versus other rentals I’ve been too! Very modern, very safe feeling, comfy pillows, the COMFIEST blanket I’ve ever used and I wish I knew where they bought it everyone I talked with was hospitable and helpful with the minor bumps we had. Overall, it was perfect for our short get away!"

Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?

Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travelers like for its sporting events and opera houses. If you're looking for a convenient place to stay, check out the 21 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Lester E. Cox Medical Center South?

Extended Stay America Select Suites Springfield South is one of the top choices for your stay based on our traveler data, and this hotel offers free parking and in-room kitchens. It's located just a short 0.5 mi (0.9 km) from Lester E. Cox Medical Center South. Other good choices close by include Residence Inn by Marriott Springfield and The Bradford Hotel, an Ascend Collection Hotel.

How many hotels are there close to Lester E. Cox Medical Center South?

Expedia has 21 hotels and other accommodations within a mile from Lester E. Cox Medical Center South.

If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?

Yes, the majority of hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the top deals on offer near Lester E. Cox Medical Center South.

Where can I learn more about changing or cancelling my trip in the area near Lester E. Cox Medical Center South?

For more information about picking new dates or cancelling your stay near Lester E. Cox Medical Center South, go to https://www.expedia.com/service/.

What can I see and do near Lester E. Cox Medical Center South?

You'll want to browse the exhibits at Discovery Center of Springfield and Springfield Art Museum. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

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Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Holiday Inn Express and Suites Springfield Medical District by IHG

4. Candlewood Suites Springfield-Medical District

5. Hilton Garden Inn Springfield, MO

6. Residence Inn by Marriott Springfield

7. Element by Marriott Springfield South

8. La Quinta Inn & Suites by Wyndham Springfield South

9. MainStay Suites Springfield South - Battlefield Rd

10. Comfort Inn South - Springfield

11. The Bradford Hotel, an Ascend Collection Hotel

12. Sleep Inn Springfield South I60 near Medical District

13. Extended Stay America Select Suites Springfield South

14. Clarion Pointe Springfield Southeast

15. Hampton Inn Springfield-Southeast

16. Holiday Inn Express & Suites Springfield North by IHG

17. SpringHill Suites by Marriott Springfield North

18. Fairfield Inn & Suites by Marriott Springfield North

19. Best Western Courtview Hotel

20. Drury Inn & Suites Springfield, MO

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Homewood Suites by Hilton Springfield Medical District

Comfort Inn South - Springfield

Peaceful Retreat near Medical Mile in Springfield

Holiday Inn Express and Suites Springfield Medical District by IHG

Cozy Central Home by CoxHealth & MSU - Fenced Yard

Sleep Inn Springfield South I60 near Medical District

Comfortable Home Near CoxHealth & MSU - Fenced Yard

Elevate Your Stay in Our Stunning Loft with 17-Foot Ceilings

Frequently asked questions

Find hotels near Lester E. Cox Medical Center South, Springfield from ￥14,046

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Holiday Inn Express and Suites Springfield Medical District by IHG

4. Candlewood Suites Springfield-Medical District

5. Hilton Garden Inn Springfield, MO

6. Residence Inn by Marriott Springfield

7. Element by Marriott Springfield South

8. La Quinta Inn & Suites by Wyndham Springfield South

9. MainStay Suites Springfield South - Battlefield Rd

10. Comfort Inn South - Springfield

11. The Bradford Hotel, an Ascend Collection Hotel

12. Sleep Inn Springfield South I60 near Medical District

13. Extended Stay America Select Suites Springfield South

14. Clarion Pointe Springfield Southeast

15. Hampton Inn Springfield-Southeast

16. Holiday Inn Express & Suites Springfield North by IHG

17. SpringHill Suites by Marriott Springfield North

18. Fairfield Inn & Suites by Marriott Springfield North

19. Best Western Courtview Hotel

20. Drury Inn & Suites Springfield, MO

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Homewood Suites by Hilton Springfield Medical District

Comfort Inn South - Springfield

Peaceful Retreat near Medical Mile in Springfield

Holiday Inn Express and Suites Springfield Medical District by IHG

Cozy Central Home by CoxHealth & MSU - Fenced Yard

Sleep Inn Springfield South I60 near Medical District

Comfortable Home Near CoxHealth & MSU - Fenced Yard

Elevate Your Stay in Our Stunning Loft with 17-Foot Ceilings

Frequently asked questions