Find hotels in La Mesa from ¥5,564

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Our top choices for La Mesa hotels

Gran Casa Sayula Hotel & Spa

Gran Casa Sayula Hotel & Spa
4.0 star property
Sayula
9.4 out of 10, Exceptional, (125)
"Great hotel in Sayula!!"
United States
Joseph
Gran Casa Sayula Hotel & Spa

Hotel Zapotlan

Hotel Zapotlan
2.5 star property
Zapotlán el Grande
8.0 out of 10, Very Good, (235)
"Rooms are ok"
United States
Noe
The price is ¥4,637
¥5,564 total
includes taxes & fees
Dec 17 - Dec 18
Hotel Zapotlan

La Casa de los Patios Hotel & Spa

La Casa de los Patios Hotel & Spa
3.5 star property
Sayula
9.4 out of 10, Exceptional, (144)
"The hotel is beautiful and staffing is great!"
United States
Tony
La Casa de los Patios Hotel & Spa

Capital O Colón, Ciudad Guzmán Jalisco

Capital O Colón, Ciudad Guzmán Jalisco
2.5 star property
Zapotlán el Grande
6.8 out of 10, (155)
"Very nice hotel, nice pool, easy to get to the center and clean"
Canada
Alex
The price is ¥4,623
¥6,057 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Capital O Colón, Ciudad Guzmán Jalisco

Tryp By Wyndham Ciudad Guzman Uttsa

Tryp By Wyndham Ciudad Guzman Uttsa
3.0 star property
Zapotlán el Grande
9.6 out of 10, Exceptional, (76)
"Excelente hotel"
Mexico
armando
The price is ¥12,024
¥14,549 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Tryp By Wyndham Ciudad Guzman Uttsa

Lofts Independencia Sayula

Lofts Independencia Sayula
2.0 star property
Sayula
5.6 out of 10, (4)
"Not satisfied charges for parking, pool and needed to ask for fresh towels n toilet paper no AC"
United States
ARTURO
The price is ¥5,325
¥6,443 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Lofts Independencia Sayula
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top La Mesa Hotel Reviews

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Frequently asked questions

What's the best place to stay in La Mesa?
Based on our traveler data, Chalet de Colombo Hotel is one of the top choices for your stay. This ranch offers free parking and free WiFi. Two other options for your visit to the area are Tryp By Wyndham Ciudad Guzman Uttsa and Hotel Zapotlan. See all available top hotels, or vacation rentals in La Mesa.
What are some of the best vacation home rentals in La Mesa?
Finca El Campanario: Located near La Mesa, this vacation home rental offers a garden and a barbecue grill to help you feel comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, an oven, and a microwave, so you can cook with friends or family. See all vacation rentals in La Mesa.
If I need to cancel my hotel reservation in La Mesa, will I receive a refund?
Yes, most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.
Where can I learn more about changing or cancelling my trip to La Mesa?
For more details about rescheduling or cancelling your trip to La Mesa, head over to our customer service page.
What's it like to stay in La Mesa?
Travelers to La Mesa will find plenty to explore and enjoy. There are 27 hotels and other accommodations in the surrounding area. Find out more about La Mesa.
What should I do while I'm visiting La Mesa?
Places to visit in the wider area include Laguna de Ciudad Guzman, Volcan Nevado de Colima National Park, and Volcano of Colima. You'll also find Las Penas Ecological Park and Nevado de Colima Trailhead in the area. Check out what more to see and do in Expedia's La Mesa guide.
What's the seasonal weather like in La Mesa?
The hottest months are usually May and April with an average temp of 70°F, while the coldest months are January and February with an average of 63°F. The rainiest months in La Mesa are August, July, September, and June, with each month seeing an average of 14 inches of rainfall.

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