A coastal landscape with a clear blue sea, a sandy beach, and a prominent pine tree in the foreground.

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Check availability on Istron Resorts & Hotels with Spas

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Istron hotels with a spa

A spa area with a hot tub and a glass-enclosed pool.

1. Daios Cove

Daios Cove
5.0 star property
Agios Nikolaos
9.4 out of 10, Exceptional, (269 reviews)
  • cleanliness
    Relax in a beachfront resort where massages and multiple pools combine with indulgent spa treatments for total rejuvenation and escape.
The price is ￥56,595
￥64,976 total
includes taxes & fees
Nov 1 - Nov 2
Daios Cove
A poolside area with lounge chairs and a pergola overlooking a mountainous landscape.

2. Istron Collection Villas

Istron Collection Villas
Agios Nikolaos
9.8 out of 10, Exceptional, (7 reviews)
  • cleanliness
    Seaside serenity awaits at this Mediterranean retreat with rejuvenating spa treatments and waterfront relaxation.
The price is ￥28,222
￥34,690 total
includes taxes & fees
Oct 30 - Oct 31
Istron Collection Villas
A pool area with palm trees, a stone wall, and modern buildings in the background.

3. Lazar Lux Suites - Ammoudara

Lazar Lux Suites - Ammoudara
Agios Nikolaos
9.6 out of 10, Exceptional, (21 reviews)
The price is ￥11,977
￥13,953 total
includes taxes & fees
Oct 31 - Nov 1
Lazar Lux Suites - Ammoudara
A modern interior with a curved seating area, a hanging light fixture, and a view into another room.

4. Minos Palace Resort - Adults Only

Minos Palace Resort - Adults Only
5.0 star property
Agios Nikolaos
9.4 out of 10, Exceptional, (288 reviews)
  • cleanliness
    Eco-certified resort offers seaside serenity with rejuvenating Ayurvedic treatments at Ananea Wellness spa.
The price is ￥37,800
￥45,567 total
includes taxes & fees
Oct 31 - Nov 1
Minos Palace Resort - Adults Only
A room with a bed, a small table, and a wall-mounted light fixture.

5. Minos Beach Art Hotel, a Member of Design Hotels

Minos Beach Art Hotel, a Member of Design Hotels
5.0 star property
Agios Nikolaos
9.4 out of 10, Exceptional, (248 reviews)
  • cleanliness
    Mediterranean serenity awaits at eco-certified spa hotel featuring private beach, outdoor pool, and sauna.
The price is ￥40,529
￥46,731 total
includes taxes & fees
Nov 6 - Nov 7
Minos Beach Art Hotel, a Member of Design Hotels
A swimming pool with sun loungers and a view of the sea and mountains.

6. Miramare Resort & Spa

Miramare Resort & Spa
4.0 star property
Agios Nikolaos
8.2 out of 10, Very good, (257 reviews)
  • cleanliness
    Pamper your body and soul at this beachfront resort spa with 4 treatment rooms, indoor pool, and rejuvenating therapies for total renewal.
The price is ￥11,066
￥14,326 total
includes taxes & fees
Oct 30 - Oct 31
Miramare Resort & Spa
A poolside view with lounge chairs, a hotel building, and a mountainous landscape in the background.

7. InterContinental Crete by IHG

InterContinental Crete by IHG
5.0 star property
Agios Nikolaos
9.0 out of 10, Wonderful, (82 reviews)
  • cleanliness
    Revitalize at this Mediterranean spa sanctuary with indoor and outdoor pools for ultimate wellness and relaxation.
The price is ￥28,662
￥35,189 total
includes taxes & fees
Oct 30 - Oct 31
InterContinental Crete by IHG
A rooftop infinity pool with lounge chairs and a bar area, overlooking the ocean.

8. Enorme Santanna Beach

Enorme Santanna Beach
4.0 star property
Ierapetra
9.4 out of 10, Exceptional, (105 reviews)
  • cleanliness
    Seaside spa retreat with beach bar and seasonal pool offers massages and facials in a garden setting.
The price is ￥22,035
￥26,783 total
includes taxes & fees
Oct 31 - Nov 1
Enorme Santanna Beach
A modern outdoor pool area with lounge chairs and a glass-enclosed pool.

9. Edem Boutique Hotel

Edem Boutique Hotel
Ammoudara
10.0 out of 10, Exceptional, (2 reviews)
The price is ￥18,174
￥20,727 total
includes taxes & fees
Nov 10 - Nov 11
Edem Boutique Hotel
A hotel entrance with a sign reading "NIKO SEA SIDE RESORT" and a "GALLERY HOTEL COLLECTION" sign.

10. NIKO Seaside Resort MGallery - Adults Only

NIKO Seaside Resort MGallery - Adults Only
5.0 star property
Agios Nikolaos
9.2 out of 10, Wonderful, (106 reviews)
  • cleanliness
    Seaside spa sanctuary boasts couples treatment rooms and Turkish baths along waterfront views.
The price is ￥24,014
￥29,909 total
includes taxes & fees
Oct 31 - Nov 1
NIKO Seaside Resort MGallery - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in Istron

Pool
Breakfast included

Top Istron Hotel Reviews

Aquila Elounda Village Resort, Suites & Spa - Adults Only

Aquila Elounda Village Resort, Suites & Spa - Adults Only

8/10 Good
"Lovely location and very helpfull staff. I would say it would not be suitable for anyone with Mobility issues because the site in built in to a steep hill so the beach and many of the facilities are some way down from the main resturant. Great Spa with lovely supportive staff."
Kay 7-night trip
Posted 3 days ago
Aquila Elounda Village Resort, Suites & Spa - Adults Only

Frequently asked questions

Looking to vacation at a spa hotel in Istron?
Treat yourself to some pampering and book a hotel with a spa. Immerse yourself in nature at the beaches and mountain views in Istron. Spa hotels are the perfect way to break out of your routine and add a layer of luxury to your holiday.
What is the best spa hotel in Istron?
Istron Bay Hotel is a top beachfront spa hotel featuring tennis courts, a hair salon, a bar, and an outdoor pool. Enjoy a facial or massage at Aegeos Spa.
How many spa hotels are there in Istron?
Among Expedia's 49 accommodation options in Istron, there is 1 spa hotel.
What's there to see and do in Istron?
Take in the sights and attractions that Istron offers with a visit to Voulisma Beach, Agios Panteleímonas, and Golden Beach. If you have extra time while you're in the area, you might want to stop by Istro Beach and Pachia Ammos Beach.
What is a Istron spa hotel?
Spa hotels in Istron have full on-site spas which offer services like couples massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.