Isle of Palms South Vacations

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Where to stay in Isle of Palms South

Find the best Isle of Palms South areas and neighborhoods for the activities you enjoy most. Learn more about Isle of Palms South
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Southside

3 out of top 10 points of interest in this area
4/5(912 area reviews)

If you're spending some time in Southside, St. Johns Town Center and The Avenues are top sights worth seeing.

Find hotels in Southside

Isle of Palms South Hotel Deals

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N, Jacksonville Beach, FL
Fully refundableReserve now, pay when you stay
9/10 Wonderful! (3,000 reviews)
Excellent Stay
"From the time we pulled up to check in every staff member was polite, informative and helpful. The hotel location is great, the ocean view amazing and decor wonderful. Our room was very large and well appointed. The hotel gym was above the normal and the swimming pool large with great music playing. ..."

Reviewed on Jul 15, 2025

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Margaritaville Jacksonville Beach
Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows

3.5 out of 5
9300 Baymeadows Road, Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is ￥16,150 per night from Jul 28 to Jul 29
￥16,150
￥18,330 total
Jul 28 - Jul 29
includes taxes & fees
8.4/10 Very Good! (1,013 reviews)
"Outside garbage pail near front entrance overflowing…… miscellaneous garbage near front door, and parking areas. Management is NOT paying attention !!!"

Reviewed on Jul 11, 2025

Embassy Suites by Hilton Jacksonville Baymeadows
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

3 out of 5
4660 Salisbury Road, I-95 Exit 344 (Butler Boulevard), Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is ￥10,631 per night from Jul 27 to Jul 28
￥10,631
￥12,066 total
Jul 27 - Jul 28
includes taxes & fees
7.6/10 Good! (1,673 reviews)
"Easy check in. Friendly staff."

Reviewed on Jul 12, 2025

Wyndham Garden Jacksonville
See all 2,908 properties in Isle of Palms South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Isle of Palms South vacation package cost?
Our Isle of Palms South vacation packages, which begin from just , are an ideal way to save precious money. Pick your favorite hotels, flights and more to create a customized getaway.
How do I get a cheap travel package to Isle of Palms South?
Just think of all the fabulous things you could do in Isle of Palms South with a wad of extra cash in your wallet. Watch your savings stack up when you combine your travel bookings into an Isle of Palms South vacation package. You have plenty of choice when you book your trip with Expedia too. In fact, you can pick from more than 550 air carriers and 1,000,000 hotels around the globe. Whether you're taking a break with the whole family or embarking on a solo adventure, planning a trip to Isle of Palms South is better with a package.
Where should I stay in Isle of Palms South?
Vacationers come from all over to experience St. Johns Town Center and University of North Florida in Isle of Palms South. Stay within walking distance of these wonderful attractions to make sightseeing easy.
How far in advance should I book my Isle of Palms South vacation?
Your best bet is to book early. Airlines generally advertise flights up to 12 months prior to departure, and this is an ideal opportunity to pick up some of the cheapest prices. Boss just told you to use up your vacation time next week? No need to worry. Expedia are never short of fantastic deals to send you off on the getaway of your dreams, at a price you can afford.
What does an Expedia Isle of Palms South travel package include?
Flights, rental cars and hotels --- we've got them all. With Expedia, you can shape your Isle of Palms South travel package just how you like it. All you have to do is decide exactly what you need. Once you've made your booking, you can add extras like tours and activities. The more you bundle, the bigger your savings!
What should I know before booking an Isle of Palms South travel package?
A travel package can be easier on the hip pocket than separately booking everything you need for your getaway. For example, bundle your hotels, flights and rental cars and land a great deal. No matter your vacation goals, you're sure to find a package that fits your budget.
Can I choose my airline with an Isle of Palms South Expedia vacation package?
Yes --- and it's easy too. Expedia has access to more than 550 partner airlines worldwide. Our packages give you the freedom to pick from available flights, hotels and activities that fit your needs.
If I'm not able to travel, can I cancel my Isle of Palms South vacation package?
If your travel plans in Isle of Palms South have changed, it's good to know that it is possible to cancel your booking. If you booked within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may charge a cancellation fee. To learn more, visit our Customer Service Portal.

Discover the most popular places to visit in Isle of Palms South

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Mayo Clinic Florida

Though Mayo Clinic Florida might be what brings you to town, perhaps you'll have a chance to explore more of Jacksonville while you are here.

Mayo Clinic Florida
Jacksonville Naval Air Station

Jacksonville Naval Air Station

After visiting Jacksonville Naval Air Station, make a plan to see the other sights and activities in Jacksonville. Experience the great live music or attend a sporting event in this family-friendly area.

Jacksonville Naval Air Station
Jacksonville Zoo and Gardens showing zoo animals

Jacksonville Zoo and Gardens

Admire thousands of animals and plants across entertaining exhibits in this family-friendly zoo that also has a children’s play area and a 4-D experience.

Jacksonville Zoo and Gardens

Things to do

Self-Guided Driving Bundle of Florida Tours

Florida's Must-See Sights: Self-Guided Driving Audio Tour Bundle

￥5,743
per traveler
100% of travellers recommend
Florida's Must-See Sights: Self-Guided Driving Audio Tour Bundle
Most beautiful sunsets on the water.

Amelia Island Floating Tiki Boat Cruise with BYOB Option

￥10,849
per adult
Amelia Island Floating Tiki Boat Cruise with BYOB Option
3 Hour Coastal Fun Cruise

3 Hour Coastal Fun Cruise

￥21,989
per adult
3 Hour Coastal Fun Cruise
See all activities in Jacksonville
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.