Find 5 Star Hotels in Santa Fe from ¥10,156
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Santa Fe 5 Star Hotels
Compare Santa Fe 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hyatt Regency Mexico City
Hyatt Regency Mexico City
9.4 out of 10, Exceptional, (1183)
The price is ¥28,352
¥33,880 total
includes taxes & fees
Sep 7 - Sep 8

Camino Real Santa Fe
Camino Real Santa Fe
9.0 out of 10, Wonderful, (2350)
The price is ¥10,156
¥12,136 total
includes taxes & fees
Sep 14 - Sep 15

Mondrian Mexico City Condesa
Mondrian Mexico City Condesa
9.2 out of 10, Wonderful, (699)
The price is ¥24,686
¥29,500 total
includes taxes & fees
Aug 31 - Sep 1

JW Marriott Hotel Mexico City Polanco
JW Marriott Hotel Mexico City Polanco
9.4 out of 10, Exceptional, (1006)
The price is ¥58,041
¥69,359 total
includes taxes & fees
Sep 5 - Sep 6

Grand Fiesta Americana Chapultepec
Grand Fiesta Americana Chapultepec
9.4 out of 10, Exceptional, (1004)
The price is ¥24,044
¥29,560 total
includes taxes & fees
Sep 20 - Sep 21

Sofitel Mexico City Reforma
Sofitel Mexico City Reforma
9.6 out of 10, Exceptional, (870)
The price is ¥67,445
¥80,597 total
includes taxes & fees
Sep 5 - Sep 6

Live Aqua Ciudad de México Bosques de las Lomas
Live Aqua Ciudad de México Bosques de las Lomas
9.6 out of 10, Exceptional, (1002)
The price is ¥41,143
¥49,166 total
includes taxes & fees
Sep 5 - Sep 6

The St. Regis Mexico City
The St. Regis Mexico City
9.6 out of 10, Exceptional, (663)
The price is ¥90,956
¥108,693 total
includes taxes & fees
Sep 1 - Sep 2
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Fe.

Camino Real Aeropuerto Mexico
Mexico City
The price is ¥19,690 per night from Sep 8 to Sep 9
¥19,690
¥23,530 total
Sep 8 - Sep 9
includes taxes & fees
8.6/10 Excellent! (11,027 reviews)
Still don't see what you're looking for?
See all properties in Santa Fe.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Santa Fe
Mexico City’s urban redevelopment jewel is this shining neighborhood on the southwest side that was once considered a dump.

Top Santa Fe Hotel Reviews

Hyatt Regency Mexico City
10/10 Excellent

Camino Real Santa Fe
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Stay near popular Santa Fe attractions
- Hotels near Santa Fe Center Mall
- Hotels near Expo Santa Fe Mexico
- Hotels near Parque La Mexicana
- Hotels near Arcos Bosques
- Hotels near Paseo de la Reforma
- Hotels near Zócalo
- Hotels near Basilica of Our Lady of Guadalupe
- Hotels near Angel of Independence Monument
- Hotels near World Trade Center Mexico City
- Hotels near Palacio de Bellas Artes
- Hotels near Auditorio Nacional
- Hotels near Frida Kahlo Museum
- Hotels near GNP Seguros Stadium
More Hotel Options in Santa Fe
Explore more hotels
- InterContinental Presidente Mexico City by IHG
- Hotel Catedral
- NH Collection Mexico City Reforma
- LaiLa Hotel CDMX
- Hotel Embassy
- Sheraton Mexico City Maria Isabel Hotel
- NH Collection Mexico City Airport T2
- Hotel PF
- Grand Prix-WeEnjoyHotels-Aeropuerto
- Geneve Ciudad de México
- Gran Hotel Ciudad de Mexico Zocalo View
- Hotel Punto MX
- Hotel Bellas Artes
- Downtown Treasure Place
- Fiesta Americana Viaducto Aeropuerto
- Marquis Reforma Hotel Spa
- Novotel México City Centro Histórico
- ULIV Pulse Roma - Condesa