A cityscape with modern high-rise buildings, including a distinctive arch structure.

Find 5 Star Hotels in Santa Fe from ￥24,197

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Fe 5 Star Hotels

Our top choices for Santa Fe 5-star hotels

A spacious lobby with a modern staircase, two armchairs, and a large abstract wall structure.

1. Hyatt Regency Mexico City

Hyatt Regency Mexico City
5.0 star property
Polanco
9.4 out of 10, Exceptional, (1,504 reviews)
"Amazing location, Amazing Staff and Great rooms !"
United States
Angel
The price is ￥53,869
￥64,374 total
includes taxes & fees
Nov 23 - Nov 24
Hyatt Regency Mexico City
A modern building with a glass facade, wooden deck, and potted plants.

2. Mondrian Mexico City Condesa

Mondrian Mexico City Condesa
5.0 star property
La Condesa
9.2 out of 10, Wonderful, (949 reviews)
"Great location and hotel. Good attention to detail by staff and in room amenities."
Canada
Carol
The price is ￥46,157
￥55,157 total
includes taxes & fees
Nov 17 - Nov 18
Mondrian Mexico City Condesa
A modern indoor seating area with sofas and chairs, a wooden railing, and large windows with geometric patterns.

3. JW Marriott Hotel Mexico City Polanco

JW Marriott Hotel Mexico City Polanco
5.0 star property
Polanco
9.4 out of 10, Exceptional, (1,001 reviews)
"Excellent"
United States
JOSE
The price is ￥106,538
￥127,313 total
includes taxes & fees
Nov 8 - Nov 9
JW Marriott Hotel Mexico City Polanco
A tall, modern hotel with a prominent vertical design, large windows, and a well-lit entrance.

4. Grand Fiesta Americana Chapultepec

Grand Fiesta Americana Chapultepec
5.0 star property
Reforma
9.6 out of 10, Exceptional, (1,270 reviews)
"Very comfy beds and great staff"
Mexico
Pablo
The price is ￥32,913
￥39,331 total
includes taxes & fees
Oct 25 - Oct 26
Grand Fiesta Americana Chapultepec
A clear blue pool with a city skyline in the background.

5. Andaz Condesa Mexico City, By Hyatt

Andaz Condesa Mexico City, By Hyatt
5.0 star property
La Condesa
9.2 out of 10, Wonderful, (463 reviews)
"Extremely friendly and helpful staff. The hotel is in a great location."
United States
Connor
The price is ￥48,851
￥58,377 total
includes taxes & fees
Nov 15 - Nov 16
Andaz Condesa Mexico City, By Hyatt
A modern indoor pool area with a clear view of the cityscape through large windows, wooden paneling, and lounge seating.

6. Sofitel Mexico City Reforma

Sofitel Mexico City Reforma
5.0 star property
Reforma
9.6 out of 10, Exceptional, (1,000 reviews)
"Excellent location and beautiful hotel"
United States
Fernando
The price is ￥85,904
￥102,656 total
includes taxes & fees
Nov 15 - Nov 16
Sofitel Mexico City Reforma
A wooden deck with seating and a vertical garden wall.

7. Live Aqua Ciudad de México Bosques de las Lomas

Live Aqua Ciudad de México Bosques de las Lomas
5.0 star property
Santa Fe
9.6 out of 10, Exceptional, (1,002 reviews)
"Great hotel, the staff is very profesional"
United States
Jose Luis
The price is ￥46,079
￥55,064 total
includes taxes & fees
Nov 15 - Nov 16
Live Aqua Ciudad de México Bosques de las Lomas
An outdoor seating area with a fire pit, surrounded by lush greenery and a view of a building with balconies.

8. Four Seasons Hotel Mexico City

Four Seasons Hotel Mexico City
5.0 star property
Reforma
9.4 out of 10, Exceptional, (1,002 reviews)
"Still close too food stands."
United States
Giovanni
The price is ￥127,653
￥152,545 total
includes taxes & fees
Nov 15 - Nov 16
Four Seasons Hotel Mexico City
A reception desk with a marble top, wooden panels, and a 'nomu' sign.

9. Nomu Mexico City by Lumina

Nomu Mexico City by Lumina
5.0 star property
Roma Norte
9.4 out of 10, Exceptional, (47 reviews)
"Great stay"
United States
Rodney
The price is ￥23,402
￥28,362 total
includes taxes & fees
Nov 16 - Nov 17
Nomu Mexico City by Lumina
A modern indoor pool area with a concrete floor, surrounded by lush greenery and a seating area with a sofa and curtains.

10. Volga, Member of Preferred Hotels & Resorts

Volga, Member of Preferred Hotels & Resorts
5.0 star property
Reforma
9.2 out of 10, Wonderful, (208 reviews)
"The staff was amazing and the space was beyond my wildest dreams! It’s in a central location and I felt very safe as a solo traveler."
United States
Dana
The price is ￥61,876
￥78,644 total
includes taxes & fees
Nov 17 - Nov 18
Volga, Member of Preferred Hotels & Resorts
A modern lounge with a panoramic city view, a circular seating area, and a bar with a unique green wall design.

11. W Mexico City

W Mexico City
5.0 star property
Polanco
8.8 out of 10, Excellent, (1,000 reviews)
"It is located in the best area of ​​Polanco, filled with restaurants, shops, and parks."
United States
Ronaldo
The price is ￥65,106
￥77,801 total
includes taxes & fees
Nov 16 - Nov 17
W Mexico City
A room with a large window, two chairs, a small round table with a cup and pastry, and a view of city buildings.

12. Hyde Mexico City Reforma

Hyde Mexico City Reforma
5.0 star property
Reforma
9.2 out of 10, Wonderful, (25 reviews)
"Excellent location"
United States
Woneui
The price is ￥28,094
￥33,572 total
includes taxes & fees
Nov 15 - Nov 16
Hyde Mexico City Reforma
A rooftop terrace with a hot tub, seating area, potted plants, and a city view.

13. Collections by ULIV Palacio

Collections by ULIV Palacio
5.0 star property
Polanco
9.4 out of 10, Exceptional, (330 reviews)
"Great location service and room highly recommend this property 11/10"
Mexico
Tarak
The price is ￥29,175
￥34,864 total
includes taxes & fees
Oct 27 - Oct 28
Collections by ULIV Palacio
A modern indoor pool area with a clear water feature, white lounge seating, and a wooden floor.

14. The Ritz-Carlton, Mexico City

The Ritz-Carlton, Mexico City
5.0 star property
Reforma
9.4 out of 10, Exceptional, (295 reviews)
"Excellent property with attentive and pleasant staff"
United States
Samuel
The price is ￥120,572
￥144,084 total
includes taxes & fees
Nov 15 - Nov 16
The Ritz-Carlton, Mexico City
A modern bedroom with a large bed, a sofa, a TV, and a view of trees through large windows.

15. Alexander, Member of The Leading Hotels of the World

Alexander, Member of The Leading Hotels of the World
5.0 star property
Miguel Hidalgo
9.4 out of 10, Exceptional, (113 reviews)
"Great hotel tos pens a short weekend"
United States
Juan Carlos
The price is ￥85,809
￥110,378 total
includes taxes & fees
Oct 25 - Oct 26
Alexander, Member of The Leading Hotels of the World
A rooftop pool with a cityscape view.

16. The St. Regis Mexico City

The St. Regis Mexico City
5.0 star property
Reforma
9.6 out of 10, Exceptional, (755 reviews)
"Todo excelente!"
Mexico
Rafael
The price is ￥125,371
￥149,819 total
includes taxes & fees
Nov 24 - Nov 25
The St. Regis Mexico City
A multi-story building with balconies, a street with light trails from moving vehicles, and a speed limit sign.

17. Kukun Sócrates Polanco

Kukun Sócrates Polanco
5.0 star property
Polanco
8.8 out of 10, Excellent, (211 reviews)
"Staff was very nice."
United States
ELODIA
The price is ￥20,134
￥24,197 total
includes taxes & fees
Oct 25 - Oct 26
Kukun Sócrates Polanco
A spiral staircase with wooden steps and patterned cushions.

18. Las Alcobas, a Luxury Collection Hotel, Mexico City

Las Alcobas, a Luxury Collection Hotel, Mexico City
5.0 star property
Polanco
9.8 out of 10, Exceptional, (314 reviews)
"Small boutique hotel in a great location "
United States
TONY
The price is ￥93,808
￥114,927 total
includes taxes & fees
Nov 2 - Nov 3
Las Alcobas, a Luxury Collection Hotel, Mexico City
A modern hotel room with a large bed, a desk, and a TV.

19. Cholula Condesa Hotel by Lumina

Cholula Condesa Hotel by Lumina
5.0 star property
La Condesa
9.6 out of 10, Exceptional, (53 reviews)
"We enjoyed our stay. The staff were very friendly & accommodating and the property was very clean. While we did enjoy our stay, there were parts of the experience that we didn’t enjoy."
United States
Antonio
The price is ￥25,389
￥31,214 total
includes taxes & fees
Oct 26 - Oct 27
Cholula Condesa Hotel by Lumina
View from room

20. Lamartine

Lamartine
5.0 star property
Polanco
9.2 out of 10, Wonderful, (192 reviews)
"Nice small hotel"
United States
Juan Pablo
The price is ￥34,775
￥42,078 total
includes taxes & fees
Oct 25 - Oct 26
Lamartine
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Fe.
Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

Mexico City
The price is ￥22,851 per night from Nov 11 to Nov 12
￥22,851
￥27,305 total
Nov 11 - Nov 12
includes taxes & fees
8.8/10 Excellent! (14,272 reviews)
Still don't see what you're looking for?
See all properties in Santa Fe.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Fe

Mexico City’s urban redevelopment jewel is this shining neighborhood on the southwest side that was once considered a dump.

See all hotels in Santa Fe
A cityscape with modern high-rise buildings, a river, and a park with a pond.

Top Santa Fe Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Santa Fe?
Live Aqua Ciudad de México Bosques de las Lomas is a favorite option around the Mexico City neighborhood of Santa Fe based on guest reviews. From its best-in-class services to its top-of-the-line amenities, this 5-star hotel promises a comfortable and luxurious stay.
How much does it cost to stay in a 5-star hotel in Santa Fe?
How much you pay for a 5-star hotel in Santa Fe can vary based on what time of year you travel and how long you plan to be away, among several factors. Use our price per night filter and other search tools to land the best rate on a high-end stay.

  • Search for the lowest price per night from ￥27,305

What makes a hotel 5 stars in Santa Fe?
Outstanding guest service is at the heart of every 5-star hotel in Santa Fe. From the minute you arrive, staff cater to your every whim, whether arranging customized tours or providing a nightly turn-down service. What's more, hotels must offer upscale conveniences to obtain a 5-star rating. These can include luxury bathrooms, a wellness center, swimming pools, gourmet kitchens and knowledgeable concierge.

Explore a world of travel with Expedia