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Find 5 Star Hotels in Lowell, MA from ￥16,959

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Check availability on Lowell 5 Star Hotels

Tonight
Dec 20 - Dec 21
Tomorrow
Dec 21 - Dec 22
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Dec 26 - Dec 28
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Jan 2 - Jan 4

Our top choices for Lowell 5-star hotels

Apartment, 2 Bedrooms | Premium bedding, down comforters, pillowtop beds, minibar
Encore Boston Harbor

Encore Boston Harbor

Encore Boston Harbor
5.0 star property
Everett
9.6 out of 10, Exceptional, (3462)
"Wonderful stay "
United States
Hosni
The price is ￥32,674
￥36,497 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Encore Boston Harbor
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lowell.
The Charles Hotel

The Charles Hotel

One Bennett Street Cambridge MA
The price is ￥52,042 per night from Jan 4 to Jan 5
￥52,042
￥60,342 total
Jan 4 - Jan 5, 2026
includes taxes & fees
9.2/10 Wonderful! (1,002 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Lowell

Wander through America's first planned industrial city where historic textile mills now house fascinating museums and art galleries. Kayak along scenic canals that once powered the Industrial Revolution or catch a Lowell Spinners baseball game during summer evenings.

See all hotels in Lowell
The History of Lowell is closely tied to its location along the Pawtucket Falls of the Merrimack River, from being an important fishing ground for the Pennacook tribe to providing water power for the factories that formed the basis of the city's economy for a century. Great place to explore and walk through history!!
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Open Photo by Dawn Madden

Top Lowell Hotel Reviews

Encore Boston Harbor

Encore Boston Harbor

10/10 Excellent
"Egg and sausge sandwich at dunkun donuts."
Daniel d 1-night trip
Posted 4 days ago
Encore Boston Harbor

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Lowell?
You'll find many different pricing options for a 5-star hotel in Lowell on Expedia. How much you'll pay will depend on when you want to travel, length of stay and other factors. Compare available accommodations for your chosen dates and make use of our pricing and other filters to find the ideal luxury stay.

  • Search for the lowest price per night from ￥16,959

What makes a hotel 5 stars in Lowell?
From high-end restaurants and all-day fitness centers to swimming pools and deluxe bedding, the 5-star experience in Lowell is all about comfort and indulgence. But it takes more than just upscale perks to earn a 5-star rating. Accommodations must also offer superior guest services like in-room massage treatments, on-site laundry and concierge services.
Are there any 5-star all-inclusive resorts in Lowell?
Use our filter tool to find an upscale escape in Lowell where everything you need is included. From there, narrow down your results for hotels that have a rating of 5 stars and are described as "All inclusive." The main thing to look forward to at these stays? Relaxation and indulgence.