Find 5 Star Hotels in Hyannis, MA from ¥26,364
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Our top choices for Hyannis 5-star hotels

Chatham Bars Inn
Chatham Bars Inn
9.2 out of 10, Wonderful, (787)
The price is ¥57,219
¥68,761 total
includes taxes & fees
Oct 14 - Oct 15

Wequassett Resort and Golf Club
Wequassett Resort and Golf Club
9.4 out of 10, Exceptional, (235)
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Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Hyannis.

Margaritaville Resort Cape Cod
1225 Iyannough Rd, Hyannis, MA
8.6/10 Excellent! (353 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Hyannis
Stroll the bustling harbor and hop aboard a ferry to Martha's Vineyard or Nantucket for a day trip. Visit the John F. Kennedy Hyannis Museum to learn about the president's connection to Cape Cod's summer playground.

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