Find 5 Star Hotels in Hyannis, MA from ￥26,364

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Check availability on Hyannis 5 Star Hotels

Tonight
Sep 20 - Sep 21
Tomorrow
Sep 21 - Sep 22
Next weekend
Sep 26 - Sep 28
In two weeks
Oct 3 - Oct 5

Compare Hyannis 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Hyannis 5-star hotels

Chatham Bars Inn
Seasonal outdoor pool

Chatham Bars Inn

5.0 star property
9.2 out of 10, Wonderful, (787)
"Very clean and happy staff"
The price is ￥57,219
￥68,761 total
includes taxes & fees
Oct 14 - Oct 15
Chatham Bars Inn
Wequassett Resort and Golf Club
6 restaurants, breakfast, lunch, dinner served; American cuisine

Wequassett Resort and Golf Club

5.0 star property
9.4 out of 10, Exceptional, (235)
"Beautiful property!! Excellent service!! Room was amazing!! "
Wequassett Resort and Golf Club
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Hyannis.
Margaritaville Resort Cape Cod

Margaritaville Resort Cape Cod

1225 Iyannough Rd, Hyannis, MA
Get rates
8.6/10 Excellent! (353 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Hyannis

Stroll the bustling harbor and hop aboard a ferry to Martha's Vineyard or Nantucket for a day trip. Visit the John F. Kennedy Hyannis Museum to learn about the president's connection to Cape Cod's summer playground.

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Hyannis showing a marina and a bay or harbor

Top Hyannis Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Hyannis?
You'll find a range of pricing options for a 5-star hotel in Hyannis on Expedia. How much you'll pay will depend on when you want to travel, length of stay and other factors. Compare all of the available accommodations for your preferred dates and make use of our pricing and other filters to find the perfect luxury stay.

  • Search for the lowest price per night from ￥26,364

What makes a hotel 5 stars in Hyannis?
Outstanding guest service is the hallmark of every 5-star hotel in Hyannis. From the minute you arrive, staff cater to your every whim, whether offering luggage assistance and storage or providing a turn-down service. Plus, hotels must offer top-rate amenities to meet the standard for a 5-star rating. These can include luxury bath products, an on-site spa, swimming pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Hyannis?
Our handy filters are the best way to find exactly what you want. Select "All inclusive" and "5-star" to show the most luxurious hotels in Hyannis where your lodging, meals, activities and entertainment are included in the price. At these stays, your vacation is pure indulgence from the moment you put down your suitcase.

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