Photo by Southernmost Illinois Tourism Bureau
Popular airlines from Des Moines to Southwest Illinois
Peach
Skymark Airlines
All Nippon Airways
Japan Airlines
Jetstar Japan
Solaseed Air
STARFLYER
- Plan, book, fly with confidence
- Be in the knowGet alerts if flight prices drop or rise*
- Book smarterSave up to 40% on select hotels after you book a flight*
Nearby Cities
Top Routes to Southwest Illinois
- Ottawa to Southwest Illinois
- Kobe to Southwest Illinois
- Sapporo to Southwest Illinois
- Washington to Southwest Illinois
- Detroit to Southwest Illinois
- Dallas to Southwest Illinois
- Incheon to Southwest Illinois
- Nagoya to Southwest Illinois
- Osaka to Southwest Illinois
- Fukuoka to Southwest Illinois
- Cleveland to Southwest Illinois
- Tokyo to Southwest Illinois
Expedia's Latest Trends
Hotels
Flights
- Flights from San Jose (SJC) to Los Angeles (LAX)
- Flights from Vancouver to Anaheim
- Flights from Cairo (CAI) to Luxor (LXR)
- Flights to Thailand
- Flights from Iwakuni to San Diego
- Flights from Chek Lap Kok (HKG) to Vancouver (YVR)
- Flights from Haneda to NYC-All Airports
- Flights from Osaka (KIX) to Phoenix (PHX)
- Flights from Wuhan (WUH) to Narita (NRT)
- Flights from Narita (NRT) to Nairobi (NBO)
*Available to Expedia members.