Flights to European Side from Madrid - ￥13,329

View ￥13,329 flight on Fri, Nov 28, 2025Opens in a new window

Popular airlines from Madrid to European Side

  • Air France

    Air France

  • ITA Airways

    ITA Airways

  • British Airways

    British Airways

  • KLM

    KLM

  • Lufthansa

    Lufthansa

  • LOT-Polish Airlines

    LOT-Polish Airlines

  • Tarom-Romanian Air Transport

    Tarom-Romanian Air Transport

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 40% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Madrid to European Side (MAD-IST)

Prices were available within the past 7 days and start at ￥13,329 for one-way flights and ￥37,840 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Tue, Feb 3 - Tue, Feb 10
MAD
Madrid
IST
Istanbul
￥37,840 Roundtrip, found 5 days ago
￥37,840
Roundtrip
found 5 days ago
Select Lufthansa flight, departing Tue, Feb 3 from Madrid to Istanbul, returning Tue, Feb 10, priced at ￥37,840 found 5 days ago
Air Europa
Fri, Jan 9 - Thu, Jan 15
MAD
Madrid
IST
Istanbul
￥45,580 Roundtrip, found 4 hours ago
￥45,580
Roundtrip
found 4 hours ago
Select Air Europa flight, departing Fri, Jan 9 from Madrid to Istanbul, returning Thu, Jan 15, priced at ￥45,580 found 4 hours ago
KLM
Fri, Jan 9 - Thu, Jan 15
MAD
Madrid
IST
Istanbul
￥48,370 Roundtrip, found 4 hours ago
￥48,370
Roundtrip
found 4 hours ago
Select KLM flight, departing Fri, Jan 9 from Madrid to Istanbul, returning Thu, Jan 15, priced at ￥48,370 found 4 hours ago
Aegean
Mon, Dec 22 - Sat, Jan 3
MAD
Madrid
IST
Istanbul
￥49,350 Roundtrip, found 4 days ago
￥49,350
Roundtrip
found 4 days ago
Select Aegean flight, departing Mon, Dec 22 from Madrid to Istanbul, returning Sat, Jan 3, priced at ￥49,350 found 4 days ago
Turkish Airlines
Fri, Jan 9 - Thu, Jan 15
MAD
Madrid
IST
Istanbul
￥55,520 Roundtrip, found 4 hours ago
￥55,520
Roundtrip
found 4 hours ago
Select Turkish Airlines flight, departing Fri, Jan 9 from Madrid to Istanbul, returning Thu, Jan 15, priced at ￥55,520 found 4 hours ago
LOT-Polish Airlines
Fri, Jan 9 - Thu, Jan 15
MAD
Madrid
IST
Istanbul
￥55,960 Roundtrip, found 4 hours ago
￥55,960
Roundtrip
found 4 hours ago
Select LOT-Polish Airlines flight, departing Fri, Jan 9 from Madrid to Istanbul, returning Thu, Jan 15, priced at ￥55,960 found 4 hours ago

Find the cheapest month to fly from Madrid (MAD) to Istanbul (IST)

February is typically the cheapest month to fly

From ￥21,667 - ￥37,447 per traveler.

Graph displaying average flight prices per month

*Available to Expedia members.