
Eastern Iowa Vacations from ¥65,215
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Find the right fit
Rest easy
The Latest Eastern Iowa Vacation Packages

The Royal Sonesta Chicago River North
Reviewed on Aug 31, 2025

Hotel Riu Plaza Chicago
Reviewed on Aug 31, 2025

Trump International Hotel & Tower Chicago
Reviewed on Aug 29, 2025

The Emily Hotel
Reviewed on Aug 22, 2025

Level Chicago – Old Town
Reviewed on Aug 27, 2025
Where to stay in Eastern Iowa

Downtown Dubuque
Take a trip through time as you stroll down the historic streets of this eastern Iowa city. Visit cafés, shops and galleries in revitalized heritage buildings.
Find the Best Eastern Iowa Vacation Packages
Eastern Iowa Hotel Deals

Hyatt Place Iowa City Downtown

La Quinta Inn & Suites by Wyndham Coralville Iowa City
Reviewed on Aug 25, 2025

Stoney Creek Hotel Quad Cities - Moline
Discover the most popular places to visit in Eastern Iowa

Amana Colonies
Explore the traditional restaurants and artisanal boutiques and learn the customs in the villages of this former self-sufficient German settlement.

Maquoketa Caves State Park
Commune with nature and explore the great outdoors at Maquoketa Caves State Park during your travels in Maquoketa. Wander the parks or discover the area's countryside.

National Mississippi River Museum and Aquarium
Learn about the region’s history and its aquatic life in one location. The role of this important river becomes apparent through the many interactive exhibits.
Other vacations you might like
Expedia's Latest Trends
- Visit Oahu
- Visit Catalina Island
- Visit Long Island
- Visit Florida Panhandle
- Visit Nantucket Island
- Visit Aleutian Islands
- Visit Northern Arkansas
- Visit Upstate New York
- Visit Greenville - Spartanburg
- Visit Silicon Valley
- Visit Whidbey Island
- Visit Bay Area
- Visit Cape Cod
- Visit Glen Canyon National Recreation Area
- Visit Napa Valley
- Visit Cape May - Wildwood