Photo by Catherine Edejer-McCormick

Find hotels in Downtown South San Francisco, San Francisco from ￥7,331

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Discover 4,802 Downtown South San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Fisherman's Wharf
Lobby sitting area
Hotel Riu Plaza Fisherman's Wharf
4.0 star property
8.8 out of 10, Excellent, 6,275 reviews
"Hotel Rui,was very nice"
The price is ￥23,271
per night
Jul 2 - Jul 3
Hotel Riu Plaza Fisherman's Wharf
DoubleTree by Hilton San Francisco South Airport Blvd
Bar (on property)
DoubleTree by Hilton San Francisco South Airport Blvd
4.0 star property
8.4 out of 10, Very Good, 1,617 reviews
"Shuttle schedule is limited "
The price is ￥19,779
per night
Jul 5 - Jul 6
DoubleTree by Hilton San Francisco South Airport Blvd
Holiday Inn Golden Gateway, an IHG Hotel
Outdoor pool, open 9:00 AM to 7:00 PM, sun loungers
Holiday Inn Golden Gateway, an IHG Hotel
3.5 star property
8.8 out of 10, Excellent, 2,610 reviews
"Excellent view. Hotel was in convenient location to Starbucks and tram. Will stay again"
The price is ￥20,302
per night
Jun 16 - Jun 17
Holiday Inn Golden Gateway, an IHG Hotel
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King George Hotel
Exterior
King George Hotel
3.0 star property
8.4 out of 10, Very Good, 1,597 reviews
"Nice place to stay—missed the bar being not opened "
The price is ￥17,023
per night
Jun 7 - Jun 8
King George Hotel
Hilton San Francisco Airport Bayfront
Courtyard
Hilton San Francisco Airport Bayfront
4.0 star property
8.2 out of 10, Very Good, 2,168 reviews
"It was a solid experience and I especially liked the food provided. The interior was nice and clean and the service was kind, and having a shuttle service between the airport and hotel saves a lot of hassel. "
The price is ￥19,923
per night
Jun 21 - Jun 22
Hilton San Francisco Airport Bayfront
The Westin St. Francis San Francisco on Union Square
Exterior
The Westin St. Francis San Francisco on Union Square
4.5 star property
9.0 out of 10, Wonderful, 2,746 reviews
"Very pleasant staff. So helpful."
The price is ￥23,613
per night
Jul 4 - Jul 5
The Westin St. Francis San Francisco on Union Square
Parc 55 San Francisco - A Hilton Hotel
Lobby
Parc 55 San Francisco - A Hilton Hotel
4.0 star property
8.6 out of 10, Excellent, 1,056 reviews
"Stayed for two nights. Very well located. "
The price is ￥19,779
per night
Jul 1 - Jul 2
Parc 55 San Francisco - A Hilton Hotel
Hotel Zephyr San Francisco
Property grounds
Hotel Zephyr San Francisco
4.0 star property
8.6 out of 10, Excellent, 1,535 reviews
"Our stay here was great as always. Love the new coffee bar near the front desk although it should be spread a little more due to backup waiting. Also, on Sunday morning, the courtyard music started loudly at 8am, on weekends, maybe wait until 9 or 10am before playing loud mus"
The price is ￥28,610
per night
Jun 17 - Jun 18
Hotel Zephyr San Francisco
Hilton San Francisco Financial District
Front of property - evening/night
Hilton San Francisco Financial District
4.0 star property
9.0 out of 10, Wonderful, 48 reviews
"Beautiful hotel and in the perfect spot to get to wherever you want to go, whether by Uber/Lyft or walking."
The price is ￥21,106
per night
Jul 2 - Jul 3
Hilton San Francisco Financial District
Hotel Caza Fisherman's Wharf
Exterior
Hotel Caza Fisherman's Wharf
4.0 star property
9.0 out of 10, Wonderful, 3,600 reviews
"Exceptional customer service. Very nice hotel right in Fisherman’s Wharf. Parking was easy."
The price is ￥26,564
per night
Jun 6 - Jun 7
Hotel Caza Fisherman's Wharf
SFO El Rancho Inn SureStay Collection by Best Western
Restaurant
SFO El Rancho Inn SureStay Collection by Best Western
3.0 star property
8.2 out of 10, Very Good, 2,230 reviews
"Close to airport. They charge $15 for parking which is not clear through booking with expedia. Rooms are comfortable overall. No airport shuttle."
The price is ￥14,515
per night
Jun 11 - Jun 12
SFO El Rancho Inn SureStay Collection by Best Western
Club Quarters Hotel in San Francisco
Terrace/patio
Club Quarters Hotel in San Francisco
4.0 star property
8.8 out of 10, Excellent, 1,610 reviews
"The location of the hotel was great, they have a wine social with a wine room next door 5-6 free wine which was great! Staff was super accommodating and helpful and remembered me when coming to ask a few questions later in the evening! Overall great experience "
The price is ￥17,428
per night
Jul 5 - Jul 6
Club Quarters Hotel in San Francisco
Hyatt Regency San Francisco
Studio, Bay View | Premium bedding, pillowtop beds, in-room safe, desk
Hyatt Regency San Francisco
4.0 star property
9.0 out of 10, Wonderful, 1,917 reviews
"Family and I had a wonderful stay. Very clean and comfortable hotel. The staff were friendly and helpful. We had a few appetizers and drinks in the evening at the restaurant and it was all very well served and delicious. The breakfast was not worth the price, in my opinion, nonetheless it was appetizing. We will be back!"
The price is ￥31,078
per night
Jun 7 - Jun 8
Hyatt Regency San Francisco
Chancellor Hotel on Union Square
Lobby sitting area
Chancellor Hotel on Union Square
3.5 star property
9.4 out of 10, Exceptional, 1,893 reviews
"I enjoyed my stay here a lot. Very comfortable and had everything I needed. Safe and convenient location which was great as I travelled solo. Would recommend!"
The price is ￥20,942
per night
Jun 16 - Jun 17
Chancellor Hotel on Union Square
LUMA Hotel San Francisco
Exterior
LUMA Hotel San Francisco
4.0 star property
9.4 out of 10, Exceptional, 1,175 reviews
"Beautiful property and friendly staff "
The price is ￥28,813
per night
Jun 7 - Jun 8
LUMA Hotel San Francisco
Hyatt Centric Fisherman's Wharf San Francisco
Terrace/patio
Hyatt Centric Fisherman's Wharf San Francisco
4.0 star property
8.6 out of 10, Excellent, 1,399 reviews
"Clean comfortable room "
The price is ￥26,549
per night
Jul 2 - Jul 3
Hyatt Centric Fisherman's Wharf San Francisco
Executive Hotel Vintage Court
Suite, 1 Bedroom, Kitchen | Private kitchen | Coffee/tea maker, eco-friendly cleaning products
Executive Hotel Vintage Court
3.0 star property
8.6 out of 10, Excellent, 1,007 reviews
"Good service. "
The price is ￥16,983
per night
Jun 7 - Jun 8
Executive Hotel Vintage Court
SF Central Hotel
Exterior
SF Central Hotel
2.0 star property
6.2 out of 10, 544 reviews
"The service was pretty good. The area was pretty good. It was a little noisy at times, but overall pretty quiet"
The price is ￥7,331
per night
Jun 5 - Jun 6
SF Central Hotel
Hotel Aluxor SFO
Exterior
Hotel Aluxor SFO
2.5 star property
8.8 out of 10, Excellent, 1,107 reviews
"Clean and basic. Does what it says on the tin."
The price is ￥16,398
per night
Jun 25 - Jun 26
Hotel Aluxor SFO
San Remo Hotel
Property grounds
San Remo Hotel
2.0 star property
8.8 out of 10, Excellent, 1,003 reviews
"We really enjoyed our stay at this hotel. Going in we knew the bathrooms were separate from the rooms so that was expected. I did not expect the cleanliness of them! I enjoyed the room provided and how accessible the hotel was to down town and parking. The room was right above the Italian restaurant downstairs and it was magical relaxing and listening to the live music. The bed was comfortable and perfect for 2. I would recommend bringing a robe or bathroom outfit for the early morning or...
The price is ￥14,324
per night
Jun 5 - Jun 6
San Remo Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Downtown South San Francisco

Hotels in top San Francisco neighborhoods Learn more about Downtown South San Francisco
Fisherman\'s Wharf showing a city and a marina

Fisherman's Wharf

1 out of top 10 points of interest in this area
4/5(38 area reviews)

This waterfront neighborhood dates back to the gold rush era and is a hub for tourist activities, sea lions and seafood restaurants.

Find hotels in Fisherman's Wharf

Downtown South San Francisco hotels information

Number of reviews
37,048
Accommodation
4,802 hotels
Lowest Price
￥7,331
Highest Price
￥31,078

Frequently asked questions

What's it like in Downtown South San Francisco?

You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood.

What's a favorite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favorite options in the area include Airport Inn and Ramada Limited San Francisco Airport North.

How many hotels will I find in the Downtown South San Francisco area?

Expedia has 42 hotels and other accommodations in Downtown South San Francisco to choose from, making this an ideal home base for exploring the greater South San Francisco area.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco.

Where can I learn more about changing or cancelling my trip to Downtown South San Francisco?

To find more details about picking new dates or cancelling your trip to Downtown South San Francisco, head over to our customer service page.

What can I see and do in this South San Francisco neighborhood?

See's Candies, K1 Speed San Francisco, and The Shops at Tanforan are just a few of the places to visit in and around Downtown South San Francisco. San Bruno Point Park and SFO Museum are also worth a visit when you're out sightseeing in South San Francisco.

Recent reviews of Downtown South San Francisco hotels

Handlery Union Square Hotel

Handlery Union Square Hotel

5/5 Excellent
"Friendly staff, clean rooms, and conveniently located to just about anything you’d want to do. "
A verified traveler stayed at Handlery Union Square Hotel
Posted 9 hours ago
Handlery Union Square Hotel