Panama's Centennial Bridge is a major bridge crossing the Panama Canal. It was built to supplement the overcrowded Bridge of the Americas and to replace it as the carrier of the Pan-American Highway. Upon its opening in 2004, it became the second permanent crossing of the canal.

The Panama Canal partial transit tour begins at the north end of the Gailard cut, where the Chagres River flows into the canal. The Gaillard Cut (also known as Culebra Cut because its curves resemble a snake) is one of the main points of interest for visitors because it was carved through the Continental Divide and this section of the Canal is full of history and geological value. Before reaching the Pedro Miguel Locks at the southern end of the Cut, you will be able to view the Centennial Bridge which crosses over the Canal. Next, the Pacific Queen will enter Pedro Miguel Locks, which is one of the two sets of locks on the Pacific side. You will then enter Miraflores Lake, which is a small artificial body of fresh water that separates Pedro Miguel from Miraflores Locks, the latter being the final set of locks before reaching the Pacific Ocean. Once in the Pacific Ocean the vessel will sail to the beautiful Flamenco Marina where passengers disembark.

The Bridge of the Americas is a road bridge in Panama, which spans the Pacific entrance to the Panama Canal. Designed by Sverdrup & Parcel, it was completed in 1962 at a cost of US$20 million, connecting the north and south American land masses.