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Find hotels in Santa Ana, Panama City from ￥5,528

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Discover 1,270 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Outdoor pool, sun loungers
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, 2,516 reviews
"It was very clean and staff was friendly "
The price is ￥17,960
per night
Jun 16 - Jun 17
Hotel Riu Plaza Panama
Decapolis Hotel Panama City
Exterior
Decapolis Hotel Panama City
4.0 star property
8.4 out of 10, Very Good, 1,012 reviews
"We arrived, checked in and went to sleep, in the morning the floor of our room was covered in water from a leaking toilet. The front desk was very efficient, and put us in an upgraded room for the remainder of our stay. The breakfast lived up to it's reputation, it had a great selection any a large selection."
The price is ￥13,606
per night
Jun 17 - Jun 18
Decapolis Hotel Panama City
Plaza Paitilla Inn Hotel
View from property
Plaza Paitilla Inn Hotel
3.5 star property
9.2 out of 10, Wonderful, 1,412 reviews
"Rooms were nice and dining area was good."
The price is ￥18,272
per night
Jun 5 - Jun 6
Plaza Paitilla Inn Hotel
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Megapolis Hotel Panamá
Front of property
Megapolis Hotel Panamá
4.5 star property
8.2 out of 10, Very Good, 423 reviews
"Great hotel with great views of the city. "
The price is ￥20,614
per night
Jun 17 - Jun 18
Megapolis Hotel Panamá
JW Marriott Panama
4 outdoor pools, cabanas (surcharge), pool umbrellas
JW Marriott Panama
5.0 star property
8.8 out of 10, Excellent, 1,005 reviews
"Excellent"
The price is ￥38,605
per night
Jun 16 - Jun 17
JW Marriott Panama
W Panama
Marvelous Suite, Suite, 1 King Bed, City View | In-room safe, blackout drapes, iron/ironing board
W Panama
5.0 star property
8.8 out of 10, Excellent, 996 reviews
"Highly recommend! Stay at the W was wonderful "
The price is ￥33,053
per night
Jun 8 - Jun 9
W Panama
Hilton Panama
Outdoor pool
Hilton Panama
5.0 star property
8.8 out of 10, Excellent, 1,008 reviews
"Excellent "
The price is ￥28,610
per night
Jul 2 - Jul 3
Hilton Panama
Novotel Panama City
Exterior
Novotel Panama City
4.0 star property
8.8 out of 10, Excellent, 1,000 reviews
"Bit dated property and maybe could be cleaner but overall comfortable "
The price is ￥13,212
per night
Jun 5 - Jun 6
Novotel Panama City
Marriott Panama Hotel
Outdoor pool, open 7:00 AM to 8:00 PM, pool umbrellas
Marriott Panama Hotel
4.0 star property
9.0 out of 10, Wonderful, 1,005 reviews
"We really liked the property, the staff was nice, they were kind, offered help literally on every task, took our luggage to the room, the breakfast was to die for, the rooftop bar with the pool, happy hour and the view was spectacular. "
The price is ￥22,434
per night
Jun 14 - Jun 15
Marriott Panama Hotel
Waldorf Astoria Panama
Outdoor pool, pool umbrellas, sun loungers
Waldorf Astoria Panama
5.0 star property
9.0 out of 10, Wonderful, 944 reviews
"Overall nice staff and property but could use some upgrades"
The price is ￥30,033
per night
Jul 3 - Jul 4
Waldorf Astoria Panama
Principe Hotel and Suites
Front of property - evening/night
Principe Hotel and Suites
3.0 star property
8.6 out of 10, Excellent, 1,000 reviews
"My family and I have a nice stay. It is located in a safe and quiet area. The staff were nice."
The price is ￥6,824
per night
Jun 12 - Jun 13
Principe Hotel and Suites
Sofitel Legend Casco Viejo, Panama City
Exterior
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8 out of 10, Exceptional, 227 reviews
"Excellent"
The price is ￥45,680
per night
Jun 6 - Jun 7
Sofitel Legend Casco Viejo, Panama City
Las Americas Golden Tower Panama
Interior entrance
Las Americas Golden Tower Panama
4.0 star property
8.8 out of 10, Excellent, 883 reviews
"It was a good stay!"
The price is ￥19,671
per night
Jun 15 - Jun 16
Las Americas Golden Tower Panama
TRYP by Wyndham Panamá Centro
Outdoor pool, pool umbrellas, sun loungers
TRYP by Wyndham Panamá Centro
3.5 star property
9.0 out of 10, Wonderful, 1,002 reviews
"Convenient location. Good restaurant. Nice rooms. Just wish the rooms were better insulated… very noisy."
The price is ￥12,059
per night
Jun 10 - Jun 11
TRYP by Wyndham Panamá Centro
Hospedium Princess Hotel Panama
Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers
Hospedium Princess Hotel Panama
3.5 star property
7.6 out of 10, Good, 272 reviews
"Close to the Airport...Easy check in process. Communication from booking to arrival Cancellation no charge policy within the stipulated time frame "
The price is ￥9,542
per night
Jun 10 - Jun 11
Hospedium Princess Hotel Panama
The Executive Hotel
Lobby
The Executive Hotel
3.5 star property
9.2 out of 10, Wonderful, 1,002 reviews
"Wonderful staff and great accommodations. "
The price is ￥16,023
per night
Jun 10 - Jun 11
The Executive Hotel
Ramada Plaza By Wyndham Panama Punta Pacífica
Outdoor pool, pool umbrellas, sun loungers
Ramada Plaza By Wyndham Panama Punta Pacífica
4.0 star property
9.4 out of 10, Exceptional, 1,006 reviews
"Good friendly and kind Good restaurant "
The price is ￥16,179
per night
Jun 14 - Jun 15
Ramada Plaza By Wyndham Panama Punta Pacífica
Euro Hotel
Outdoor pool
Euro Hotel
3.0 star property
7.6 out of 10, Good, 523 reviews
"The hotel was well worth the money I paid. Restaurant was nice for breakfast. The hotel was clean and staff was friendly. "
The price is ￥5,528
per night
Jun 18 - Jun 19
Euro Hotel
AC Hotel by Marriott Panama City
Exterior
AC Hotel by Marriott Panama City
3.5 star property
9.0 out of 10, Wonderful, 423 reviews
"Javier and the staff are great"
The price is ￥14,867
per night
Jun 29 - Jun 30
AC Hotel by Marriott Panama City
Central Hotel Panama Casco Viejo
Flat-screen TV
Central Hotel Panama Casco Viejo
4.0 star property
9.0 out of 10, Wonderful, 687 reviews
"Fantastic staff. Junior suite room comfortable but small. I would stay here again. "
The price is ￥34,786
per night
Jun 5 - Jun 6
Central Hotel Panama Casco Viejo
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Other neighborhoods around Santa Ana

Hotels in top Panama City neighborhoods Learn more about Santa Ana
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Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or National Theater while you're exploring the area.

Find hotels in Casco Viejo

Santa Ana hotels information

Number of reviews
18,352
Accommodation
1,270 hotels
Lowest Price
￥5,528
Highest Price
￥45,680

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Avenida Central and Cinta Costera while you're in the neighborhood.

Where is the best hotel for a stay in Santa Ana?

Based on Expedia customer reviews, Hotel República is a highly ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.

How many hotels can I expect to find in Santa Ana?

Expedia has 88 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.

What is there to do in this Panama City neighborhood?

If you're looking forward to a day of shopping in Santa Ana, consider Avenida Central or Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighborhood. Albrook Shopping Mall, Amador Theater, and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.

Recent reviews of Santa Ana hotels

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5/5 Excellent
"It was very clean and staff was friendly "
A verified traveler stayed at Hotel Riu Plaza Panama
Posted 2 days ago
Hotel Riu Plaza Panama